[Hub]/) : Traits : Forced vital capacity (FVC), Best measure : ← →

chr2:23,453,834-25,889,403

Best TWAS P=9.82e-19 · Best GWAS P=1.95e-17 conditioned to 0.565

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	GTEx	Cells EBV-transformed lymphocytes	ADCY3	0.25	0.23	enet	10	0.12	9.2e-05	-7.9	8.8	9.8e-19	-0.77	0.07	0.92	TRUE
23	GTEx	Spleen	UBXN2A	0.31	0.11	enet	19	0.17	4.1e-05	6.8	-7.5	8.2e-14	0.14	0.04	0.92	TRUE
16	GTEx	Lung	NCOA1	0.12	0.04	lasso	7	0.06	1.9e-05	-2.0	-6.2	4.7e-10	0.23	0.52	0.03	TRUE
29	ROSMAP	Brain Pre-frontal Cortex	ADCY3	0.17	0.26	enet	32	0.26	6.8e-33	-8.1	8.8	1.1e-18	-0.80	0.04	0.96	FALSE
13	GTEx	Cells EBV-transformed lymphocytes	RP11-443B20.1	0.13	0.13	enet	9	0.05	9.2e-03	-7.9	8.7	5.0e-18	-0.83	0.05	0.87	FALSE
19	GTEx	Nerve Tibial	ADCY3	0.09	0.05	enet	6	0.03	2.2e-03	-6.9	8.5	2.2e-17	-0.81	0.06	0.94	FALSE
26	GTEx	Whole Blood	ADCY3	0.23	0.24	enet	24	0.27	5.5e-25	-8.1	-8.1	4.7e-16	0.76	0.05	0.95	FALSE
33	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADCY3	0.03	0.02	blup	81	0.02	7.1e-04	-6.3	7.9	2.5e-15	-0.77	0.07	0.87	FALSE
25	GTEx	Whole Blood	DNAJC27	0.08	0.10	lasso	1	0.10	2.2e-09	-7.8	-7.8	6.0e-15	0.69	0.11	0.89	FALSE
28	GTEx	Whole Blood	RP11-443B20.1	0.21	0.17	enet	32	0.20	1.8e-18	-7.8	-7.8	7.4e-15	0.77	0.08	0.92	FALSE
20	GTEx	Nerve Tibial	RP11-443B20.1	0.07	0.03	enet	6	0.02	1.1e-02	-6.9	7.8	8.0e-15	-0.71	0.08	0.89	FALSE
3	GTEx	Adipose Subcutaneous	ADCY3	0.07	0.04	lasso	6	0.01	3.2e-02	-7.9	-7.6	4.2e-14	0.75	0.06	0.94	FALSE
15	GTEx	Esophagus Muscularis	NCOA1	0.11	0.01	enet	9	0.01	5.8e-02	-5.5	-7.5	4.3e-14	0.48	0.08	0.13	FALSE
9	GTEx	Artery Tibial	ADCY3	0.21	0.14	lasso	6	0.15	4.3e-12	-6.9	-7.3	2.3e-13	0.63	0.68	0.32	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ADCY3	0.16	0.12	lasso	10	0.14	3.2e-17	-8.1	7.2	5.3e-13	-0.80	0.05	0.95	FALSE
27	GTEx	Whole Blood	UBXN2A	0.17	0.07	lasso	8	0.09	2.1e-08	-4.2	-7.1	9.2e-13	0.12	0.03	0.97	FALSE
8	GTEx	Artery Aorta	NCOA1	0.15	0.00	enet	15	0.01	1.4e-01	-6.0	-6.9	4.9e-12	0.31	0.07	0.14	FALSE
14	GTEx	Colon Transverse	UBXN2A	0.11	0.01	enet	8	0.03	8.7e-03	-6.2	-6.8	1.1e-11	0.12	0.07	0.72	FALSE
2	CommonMind	Brain Pre-frontal Cortex	CENPO	0.07	0.03	bslmm	322	0.03	7.0e-05	-3.4	6.7	1.6e-11	-0.52	0.48	0.24	FALSE
30	The Cancer Genome Atlas	Breast Invasive Carcinoma	ADCY3	0.05	0.03	blup	81	0.03	5.0e-07	-4.5	6.5	8.8e-11	-0.48	0.69	0.25	FALSE
11	GTEx	Artery Tibial	RP11-443B20.1	0.17	0.08	enet	40	0.09	8.2e-08	-6.9	-6.4	1.2e-10	0.54	0.20	0.78	FALSE
31	The Cancer Genome Atlas	Glioblastoma Multiforme	ADCY3	0.36	0.14	enet	7	0.13	8.9e-05	-5.8	6.4	1.9e-10	-0.32	0.04	0.18	FALSE
10	GTEx	Artery Tibial	UBXN2A	0.12	0.06	enet	24	0.09	1.5e-07	-3.9	-6.4	2.0e-10	0.12	0.76	0.24	FALSE
22	GTEx	Small Intestine Terminal Ileum	UBXN2A	0.18	0.08	enet	33	0.16	2.5e-04	-6.4	-6.3	3.2e-10	0.15	0.03	0.90	FALSE
17	GTEx	Lung	UBXN2A	0.09	0.06	enet	7	0.07	6.1e-06	-4.2	-6.3	3.8e-10	0.11	0.25	0.74	FALSE
7	GTEx	Adrenal Gland	PTRHD1	0.32	0.28	lasso	3	0.26	8.3e-10	5.9	-5.9	3.3e-09	0.39	0.98	0.00	FALSE
4	GTEx	Adipose Subcutaneous	UBXN2A	0.06	0.04	lasso	5	0.04	5.2e-04	-6.3	-5.9	3.5e-09	0.09	0.26	0.71	FALSE
6	GTEx	Adipose Visceral Omentum	UBXN2A	0.10	0.08	enet	29	0.03	9.8e-03	-6.5	-5.9	3.5e-09	0.10	0.08	0.90	FALSE
21	GTEx	Skin Sun Exposed Lower leg	UBXN2A	0.08	0.04	enet	17	0.03	1.3e-03	-6.3	-5.8	7.5e-09	0.11	0.58	0.33	FALSE
35	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	UBXN2A	0.03	0.02	blup	46	0.03	5.7e-04	-4.2	-5.7	1.4e-08	0.09	0.26	0.40	FALSE
32	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ADCY3	0.08	0.03	enet	16	0.03	1.5e-04	-4.6	5.5	3.0e-08	-0.10	0.03	0.08	FALSE
18	GTEx	Muscle Skeletal	UBXN2A	0.10	0.04	lasso	7	0.03	5.5e-04	-4.2	-5.4	7.4e-08	0.09	0.26	0.74	FALSE
34	The Cancer Genome Atlas	Lung Adenocarcinoma	DNAJC27	0.05	0.01	blup	46	0.04	3.2e-05	-2.7	5.3	1.4e-07	-0.52	0.56	0.35	FALSE
24	GTEx	Stomach	UBXN2A	0.13	0.14	enet	5	0.14	3.6e-07	-3.9	-5.2	1.7e-07	0.09	0.58	0.31	FALSE
36	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	EFR3B	0.26	0.01	lasso	4	0.05	3.8e-03	-5.5	-5.2	1.7e-07	0.41	0.03	0.16	FALSE
5	GTEx	Adipose Subcutaneous	RP11-443B20.1	0.04	0.00	enet	10	0.00	1.2e-01	-2.3	-5.2	2.4e-07	0.71	0.05	0.88	FALSE