Best TWAS P=3.32e-08 · Best GWAS P=6.01e-07 conditioned to 0.0116
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | GPX1 | 0.31 | 0.09 | enet | 19 | 0.23 | 2.0e-07 | 4.8 | -5.4 | 8.0e-08 | -0.50 | 0.04 | 0.94 | FALSE |
| 2 | GTEx | Brain Frontal Cortex BA9 | GPX1 | 0.16 | 0.06 | lasso | 6 | 0.15 | 7.9e-05 | -4.0 | -5.5 | 3.3e-08 | -0.62 | 0.05 | 0.75 | TRUE |
| 3 | GTEx | Colon Transverse | RNF123 | 0.16 | 0.05 | enet | 36 | 0.05 | 2.3e-03 | -3.8 | -5.4 | 6.8e-08 | -0.15 | 0.14 | 0.30 | TRUE |
| 4 | GTEx | Lung | RNF123 | 0.13 | 0.05 | enet | 18 | 0.07 | 5.8e-06 | -4.2 | -5.2 | 2.0e-07 | -0.32 | 0.18 | 0.72 | FALSE |
| 5 | GTEx | Lung | GPX1 | 0.04 | 0.02 | enet | 13 | 0.04 | 5.7e-04 | 4.6 | -5.5 | 3.6e-08 | -0.52 | 0.05 | 0.71 | FALSE |
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | AMIGO3 | 0.01 | 0.00 | enet | 13 | 0.01 | 5.7e-03 | -3.8 | -5.2 | 2.5e-07 | -0.41 | 0.01 | 0.20 | FALSE |