Best TWAS P=3.33e-08 · Best GWAS P=1.35e-06 conditioned to 0.0483
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adrenal Gland | RFT1 | 0.15 | 0.02 | enet | 11 | 0.03 | 4.0e-02 | 4.7 | 5.5 | 3.3e-08 | -0.58 | 0.03 | 0.79 | TRUE |
2 | GTEx | Testis | RP5-966M1.6 | 0.14 | 0.10 | lasso | 6 | 0.09 | 6.1e-05 | -4.7 | -5.4 | 8.4e-08 | 0.95 | 0.03 | 0.94 | FALSE |
3 | ROSMAP | Brain Pre-frontal Cortex | SFMBT1 | 0.07 | 0.02 | bslmm | 340 | 0.03 | 2.9e-04 | -3.1 | -5.4 | 7.1e-08 | 0.62 | 0.08 | 0.77 | FALSE |