[Hub]/) : Traits : Forced vital capacity (FVC), Best measure : ← →

chr4:2,811,841-4,219,590

Best TWAS P=3.95e-11 · Best GWAS P=1.3e-09 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	GTEx	Skin Sun Exposed Lower leg	LRPAP1	0.13	0.03	enet	12	0.08	3.6e-07	-3.0	-6.6	3.9e-11	-0.42	0.35	0.56	TRUE
2	GTEx	Artery Aorta	LRPAP1	0.20	0.13	lasso	3	0.13	1.7e-07	5.8	-6.4	1.5e-10	-0.98	0.01	0.99	TRUE
18	The Cancer Genome Atlas	Thyroid Carcinoma	RGS12	0.08	0.01	blup	108	0.01	2.4e-02	-5.5	-5.8	7.0e-09	-0.01	0.00	0.79	TRUE
17	The Cancer Genome Atlas	Soft Tissue Sarcoma	LRPAP1	0.12	0.02	blup	52	0.05	6.6e-04	1.3	-6.5	5.7e-11	-0.42	0.04	0.25	FALSE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	LRPAP1	0.12	0.09	blup	52	0.12	1.5e-12	5.9	-6.3	2.8e-10	-0.80	0.01	0.99	FALSE
1	GTEx	Adipose Subcutaneous	LRPAP1	0.16	0.04	lasso	4	0.04	1.6e-04	5.9	-6.3	3.1e-10	-0.85	0.01	0.96	FALSE
10	GTEx	Nerve Tibial	LRPAP1	0.29	0.11	enet	16	0.14	7.6e-10	5.8	-6.3	3.7e-10	-0.85	0.01	0.99	FALSE
4	GTEx	Artery Tibial	LRPAP1	0.36	0.21	lasso	7	0.21	3.5e-16	6.1	-6.2	4.9e-10	-0.98	0.00	1.00	FALSE
12	GTEx	Thyroid	LRPAP1	0.28	0.07	lasso	8	0.15	2.6e-11	6.1	-6.1	8.6e-10	-0.82	0.00	1.00	FALSE
15	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LRPAP1	0.05	0.00	blup	52	0.02	2.8e-02	-2.3	-6.1	1.3e-09	-0.38	0.04	0.17	FALSE
3	GTEx	Artery Coronary	LRPAP1	0.24	0.13	lasso	2	0.07	2.1e-03	6.1	-6.0	1.6e-09	-1.00	0.01	0.98	FALSE
8	GTEx	Esophagus Muscularis	LRPAP1	0.22	0.03	lasso	7	0.02	1.1e-02	5.9	-6.0	2.7e-09	-0.93	0.01	0.99	FALSE
5	GTEx	Brain Cerebellar Hemisphere	LRPAP1	0.53	0.04	lasso	11	0.17	4.1e-05	-2.8	-5.9	2.8e-09	-0.36	0.07	0.37	FALSE
14	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	LRPAP1	0.08	0.01	blup	52	0.04	2.9e-03	-3.0	-5.7	1.0e-08	-0.57	0.02	0.47	FALSE
9	GTEx	Muscle Skeletal	LRPAP1	0.16	0.04	enet	23	0.09	4.4e-09	5.9	-5.7	1.4e-08	-0.66	0.01	0.99	FALSE
7	GTEx	Cells Transformed fibroblasts	LRPAP1	0.35	0.20	lasso	4	0.26	2.3e-19	4.8	-5.7	1.6e-08	-0.91	0.01	0.99	FALSE
6	GTEx	Brain Cerebellum	LRPAP1	0.54	0.03	lasso	10	0.18	7.3e-06	-3.0	-5.3	9.2e-08	-0.27	0.09	0.33	FALSE
13	METSIM	Adipose	LRPAP1	0.14	0.12	lasso	4	0.12	4.4e-17	4.8	-5.2	2.2e-07	-0.94	0.02	0.98	FALSE