[Hub]/) : Traits : Forced vital capacity (FVC), Best measure :

chr4:2,811,841-4,219,590

Best TWAS P=3.95e-11 · Best GWAS P=1.3e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous LRPAP1 0.16 0.04 lasso 4 0.04 1.6e-04 5.9 -6.3 3.1e-10 -0.85 0.01 0.96 FALSE
2 GTEx Artery Aorta LRPAP1 0.20 0.13 lasso 3 0.13 1.7e-07 5.8 -6.4 1.5e-10 -0.98 0.01 0.99 TRUE
3 GTEx Artery Coronary LRPAP1 0.24 0.13 lasso 2 0.07 2.1e-03 6.1 -6.0 1.6e-09 -1.00 0.01 0.98 FALSE
4 GTEx Artery Tibial LRPAP1 0.36 0.21 lasso 7 0.21 3.5e-16 6.1 -6.2 4.9e-10 -0.98 0.00 1.00 FALSE
5 GTEx Brain Cerebellar Hemisphere LRPAP1 0.53 0.04 lasso 11 0.17 4.1e-05 -2.8 -5.9 2.8e-09 -0.36 0.07 0.37 FALSE
6 GTEx Brain Cerebellum LRPAP1 0.54 0.03 lasso 10 0.18 7.3e-06 -3.0 -5.3 9.2e-08 -0.27 0.09 0.33 FALSE
7 GTEx Cells Transformed fibroblasts LRPAP1 0.35 0.20 lasso 4 0.26 2.3e-19 4.8 -5.7 1.6e-08 -0.91 0.01 0.99 FALSE
8 GTEx Esophagus Muscularis LRPAP1 0.22 0.03 lasso 7 0.02 1.1e-02 5.9 -6.0 2.7e-09 -0.93 0.01 0.99 FALSE
9 GTEx Muscle Skeletal LRPAP1 0.16 0.04 enet 23 0.09 4.4e-09 5.9 -5.7 1.4e-08 -0.66 0.01 0.99 FALSE
10 GTEx Nerve Tibial LRPAP1 0.29 0.11 enet 16 0.14 7.6e-10 5.8 -6.3 3.7e-10 -0.85 0.01 0.99 FALSE
11 GTEx Skin Sun Exposed Lower leg LRPAP1 0.13 0.03 enet 12 0.08 3.6e-07 -3.0 -6.6 3.9e-11 -0.42 0.35 0.56 TRUE
12 GTEx Thyroid LRPAP1 0.28 0.07 lasso 8 0.15 2.6e-11 6.1 -6.1 8.6e-10 -0.82 0.00 1.00 FALSE
13 METSIM Adipose LRPAP1 0.14 0.12 lasso 4 0.12 4.4e-17 4.8 -5.2 2.2e-07 -0.94 0.02 0.98 FALSE
14 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma LRPAP1 0.08 0.01 blup 52 0.04 2.9e-03 -3.0 -5.7 1.0e-08 -0.57 0.02 0.47 FALSE
15 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LRPAP1 0.05 0.00 blup 52 0.02 2.8e-02 -2.3 -6.1 1.3e-09 -0.38 0.04 0.17 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma LRPAP1 0.12 0.09 blup 52 0.12 1.5e-12 5.9 -6.3 2.8e-10 -0.80 0.01 0.99 FALSE
17 The Cancer Genome Atlas Soft Tissue Sarcoma LRPAP1 0.12 0.02 blup 52 0.05 6.6e-04 1.3 -6.5 5.7e-11 -0.42 0.04 0.25 FALSE
18 The Cancer Genome Atlas Thyroid Carcinoma RGS12 0.08 0.01 blup 108 0.01 2.4e-02 -5.5 -5.8 7.0e-09 -0.01 0.00 0.79 TRUE