[Hub]/) : Traits : Forced vital capacity (FVC), Best measure :

chr4:17,104,059-18,507,692

Best TWAS P=3.47e-47 · Best GWAS P=1.83e-42 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous DCAF16 0.21 0.15 lasso 3 0.17 5.1e-14 9.41 9.1 8.9e-20 -0.23 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum DCAF16 0.19 0.06 enet 10 0.11 3.9e-06 9.41 10.0 1.3e-23 -0.35 0.36 0.32 FALSE
3 GTEx Artery Aorta DCAF16 0.10 0.01 enet 6 0.02 4.7e-02 -12.65 14.3 1.6e-46 -0.79 0.09 0.64 FALSE
4 GTEx Artery Tibial DCAF16 0.16 0.16 lasso 5 0.13 1.5e-10 9.85 11.1 1.1e-28 -0.35 1.00 0.00 FALSE
5 GTEx Breast Mammary Tissue DCAF16 0.12 0.08 lasso 4 0.10 6.4e-06 9.46 12.1 6.1e-34 -0.51 0.09 0.77 FALSE
6 GTEx Breast Mammary Tissue (Male) DCAF16 0.24 0.03 enet 18 -0.01 4.4e-01 -12.50 14.4 3.5e-47 -0.75 0.03 0.66 TRUE
7 GTEx Breast Mammary Tissue (Female) DCAF16 0.16 0.13 lasso 2 0.06 7.8e-03 9.41 9.3 1.8e-20 -0.26 0.06 0.10 FALSE
8 GTEx Esophagus Mucosa DCAF16 0.10 0.02 lasso 4 0.02 8.3e-03 9.46 10.2 2.3e-24 -0.35 0.14 0.37 FALSE
9 GTEx Esophagus Muscularis DCAF16 0.16 0.14 lasso 3 0.14 9.3e-09 9.41 9.3 1.2e-20 -0.25 0.99 0.00 FALSE
10 GTEx Nerve Tibial DCAF16 0.16 0.14 lasso 3 0.14 2.8e-10 9.41 10.7 1.5e-26 -0.35 0.99 0.00 FALSE
11 GTEx Pituitary DCAF16 0.27 0.20 enet 15 0.19 1.3e-05 9.41 8.8 9.1e-19 -0.37 0.08 0.24 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic DCAF16 0.16 0.08 lasso 5 0.12 4.4e-07 7.81 9.2 2.7e-20 -0.34 0.63 0.05 TRUE
13 GTEx Skin Sun Exposed Lower leg DCAF16 0.14 0.12 enet 14 0.12 5.4e-10 9.46 9.9 3.0e-23 -0.27 1.00 0.00 FALSE
14 GTEx Spleen DCAF16 0.35 0.02 lasso 5 0.11 8.5e-04 9.41 13.7 9.6e-43 -0.65 0.04 0.66 TRUE
15 GTEx Stomach DCAF16 0.21 0.04 lasso 6 0.02 5.6e-02 9.82 11.1 7.5e-29 -0.24 0.19 0.05 FALSE
16 GTEx Thyroid DCAF16 0.11 0.02 lasso 5 0.03 2.3e-03 9.41 12.8 1.3e-37 -0.53 0.16 0.71 TRUE
17 ROSMAP Brain Pre-frontal Cortex DCAF16 0.04 0.02 bslmm 379 0.01 3.9e-02 -12.60 12.4 3.4e-35 -0.83 0.03 0.88 TRUE
18 YFS Blood DCAF16 0.02 0.02 lasso 1 0.01 1.1e-04 9.85 9.8 7.1e-23 -0.25 0.84 0.03 FALSE
19 The Cancer Genome Atlas Breast Invasive Carcinoma NCAPG 0.03 0.04 enet 5 0.04 8.1e-09 -0.78 -5.4 5.2e-08 0.56 0.96 0.04 FALSE
20 The Cancer Genome Atlas Colon Adenocarcinoma NCAPG 0.08 0.04 blup 34 0.09 1.1e-05 -12.68 -10.7 7.3e-27 0.83 0.04 0.94 FALSE
21 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NCAPG 0.14 0.07 lasso 3 0.07 5.2e-08 -12.60 -12.2 2.1e-34 0.83 0.89 0.10 TRUE
22 The Cancer Genome Atlas Brain Lower Grade Glioma DCAF16 0.09 0.02 lasso 3 0.04 5.2e-05 9.85 13.9 8.1e-44 -0.63 0.05 0.87 FALSE
23 The Cancer Genome Atlas Brain Lower Grade Glioma NCAPG 0.02 0.03 lasso 1 0.02 9.0e-04 -12.68 -12.7 7.3e-37 0.87 0.04 0.43 FALSE
24 The Cancer Genome Atlas Lung Adenocarcinoma NCAPG 0.06 0.02 blup 34 0.04 1.0e-05 -12.68 -7.5 5.3e-14 0.68 0.13 0.07 TRUE
25 The Cancer Genome Atlas Prostate Adenocarcinoma DCAF16 0.04 0.04 blup 31 0.04 2.2e-05 9.41 13.0 8.3e-39 -0.56 0.27 0.23 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma NCAPG 0.02 0.02 blup 34 0.02 3.4e-03 -12.26 -11.1 1.6e-28 0.75 0.01 0.75 FALSE
27 The Cancer Genome Atlas Thyroid Carcinoma DCAF16 0.07 0.04 blup 31 0.07 4.9e-07 9.82 13.4 8.1e-41 -0.64 0.15 0.77 FALSE