Best TWAS P=1.8e-08 · Best GWAS P=1.46e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | NOA1 | 0.17 | 0.06 | lasso | 4 | 0.06 | 3.5e-04 | 5.0 | -5.5 | 4.4e-08 | 0.90 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Muscle Skeletal | REST | 0.05 | 0.01 | enet | 9 | 0.02 | 3.9e-03 | -3.9 | -5.2 | 2.4e-07 | 0.85 | 0.02 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | C4orf14 | 0.03 | 0.04 | lasso | 3 | 0.04 | 1.9e-05 | -5.7 | -5.6 | 1.8e-08 | 0.99 | 0.00 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | REST | 0.04 | 0.01 | lasso | 5 | 0.02 | 7.8e-04 | -4.6 | -5.6 | 2.3e-08 | 0.77 | 0.11 | 0.47 | FALSE |