Best TWAS P=4.1e-26 · Best GWAS P=6.19e-27 conditioned to 0.00976
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | OTUD4 | 0.06 | 0.04 | bslmm | 272 | 0.04 | 2.6e-05 | -6.8 | -7.1 | 1.2e-12 | 0.66 | 0.15 | 0.83 | FALSE |
| 2 | GTEx | Brain Hypothalamus | HHIP-AS1 | 0.12 | 0.02 | enet | 16 | 0.04 | 4.6e-02 | 8.7 | 6.5 | 6.7e-11 | -0.52 | 0.04 | 0.41 | FALSE |
| 3 | GTEx | Pancreas | ANAPC10 | 0.14 | 0.10 | lasso | 3 | 0.10 | 4.3e-05 | -10.6 | 10.6 | 4.1e-26 | -0.79 | 0.02 | 0.95 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | OTUD4 | 0.04 | 0.03 | lasso | 2 | 0.03 | 1.4e-04 | 7.0 | -7.2 | 5.0e-13 | 0.47 | 0.60 | 0.11 | TRUE |