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Traits
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Forced vital capacity (FVC), Best measure
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chr4:144,882,744-146,788,825
Best TWAS P=4.1e-26 · Best GWAS P=6.19e-27 conditioned to 0.00976
145M
145.5M
146M
146.5M
0
5
10
15
20
25
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Pancreas
ANAPC10
0.14
0.10
lasso
3
0.10
4.3e-05
-10.6
10.6
4.1e-26
-0.79
0.02
0.95
TRUE
4
ROSMAP
Brain Pre-frontal Cortex
OTUD4
0.04
0.03
lasso
2
0.03
1.4e-04
7.0
-7.2
5.0e-13
0.47
0.60
0.11
TRUE
1
CommonMind
Brain Pre-frontal Cortex
OTUD4
0.06
0.04
bslmm
272
0.04
2.6e-05
-6.8
-7.1
1.2e-12
0.66
0.15
0.83
FALSE
2
GTEx
Brain Hypothalamus
HHIP-AS1
0.12
0.02
enet
16
0.04
4.6e-02
8.7
6.5
6.7e-11
-0.52
0.04
0.41
FALSE