Best TWAS P=2.18e-10 · Best GWAS P=1.35e-08 conditioned to 0.000371
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Colon Transverse | SAR1B | 0.11 | 0.00 | enet | 17 | 0.03 | 1.2e-02 | -4.51 | -5.5 | 4.2e-08 | -0.01 | 0.06 | 0.10 | TRUE |
2 | GTEx | Muscle Skeletal | CAMLG | 0.08 | 0.01 | enet | 28 | 0.05 | 2.0e-05 | 0.34 | -5.6 | 1.7e-08 | 0.38 | 0.03 | 0.43 | TRUE |
3 | METSIM | Adipose | SAR1B | 0.06 | 0.02 | bslmm | 288 | 0.03 | 3.1e-05 | -4.64 | -6.3 | 2.2e-10 | 0.32 | 0.35 | 0.35 | TRUE |