[Hub]/) : Traits : Forced vital capacity (FVC), Best measure : ← →

chr5:139,323,257-141,214,127

Best TWAS P=1.76e-09 · Best GWAS P=1.05e-07 conditioned to 0.354

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	GTEx	Heart Left Ventricle	PCDHB5	0.11	0.05	lasso	3	0.06	5.3e-04	4.6	6.0	1.8e-09	-0.79	0.07	0.76	TRUE
4	CommonMind	Brain Pre-frontal Cortex	ZMAT2	0.06	0.10	blup	360	0.09	1.4e-11	-5.1	-5.9	3.8e-09	0.86	0.07	0.93	FALSE
9	GTEx	Cells Transformed fibroblasts	ZMAT2	0.04	0.02	lasso	4	0.02	2.4e-02	-5.3	-5.4	5.1e-08	0.96	0.06	0.86	FALSE
11	GTEx	Heart Left Ventricle	TMCO6	0.05	0.01	lasso	5	0.00	6.2e-01	-5.1	-5.4	5.4e-08	0.91	0.06	0.74	FALSE
10	GTEx	Esophagus Mucosa	ZMAT2	0.06	0.02	enet	16	0.02	1.1e-02	4.8	-5.4	6.5e-08	0.77	0.08	0.81	FALSE
21	The Cancer Genome Atlas	Lung Adenocarcinoma	PCDHA13	0.02	0.01	enet	11	0.02	5.6e-03	4.7	5.4	6.8e-08	-0.64	0.02	0.77	FALSE
13	GTEx	Nerve Tibial	HARS	0.07	0.01	enet	16	0.04	1.1e-03	-5.3	5.4	6.9e-08	-0.84	0.06	0.90	FALSE
1	CommonMind	Brain Pre-frontal Cortex	NDUFA2	0.02	0.01	bslmm	343	0.01	7.8e-03	-5.2	5.4	7.9e-08	-0.89	0.08	0.69	FALSE
15	METSIM	Adipose	DND1	0.08	0.11	lasso	5	0.10	7.3e-15	-5.3	5.3	9.5e-08	-0.97	0.06	0.94	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	PCDHA4	0.01	0.02	lasso	1	0.01	4.9e-04	-5.3	-5.3	1.1e-07	0.99	0.00	0.96	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	PCDHA8	0.04	0.03	enet	4	0.03	3.4e-05	-5.1	-5.3	1.2e-07	0.87	0.04	0.96	FALSE
6	GTEx	Brain Cerebellar Hemisphere	WDR55	0.11	0.07	enet	10	-0.01	6.6e-01	-4.6	-5.3	1.3e-07	0.88	0.08	0.61	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PCDHA2	0.04	0.03	blup	478	0.03	5.0e-05	-5.1	-5.3	1.5e-07	0.84	0.08	0.92	FALSE
5	GTEx	Artery Tibial	TMCO6	0.04	0.04	enet	5	0.04	4.1e-04	4.5	-5.2	1.9e-07	0.80	0.12	0.87	FALSE
8	GTEx	Cells Transformed fibroblasts	WDR55	0.05	0.08	lasso	13	0.07	4.0e-06	-5.1	-5.2	1.9e-07	0.91	0.08	0.92	FALSE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZMAT2	0.03	0.03	enet	6	0.04	1.3e-04	-5.0	-5.2	1.9e-07	0.89	0.02	0.89	FALSE
3	CommonMind	Brain Pre-frontal Cortex	PCDHA7	0.13	0.14	lasso	8	0.14	5.1e-17	-5.2	-5.2	2.0e-07	0.97	0.05	0.95	FALSE
14	GTEx	Vagina	IK	0.27	0.09	enet	29	0.15	2.4e-04	-4.5	-5.1	2.7e-07	0.82	0.10	0.85	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PCDHA7	0.02	0.02	enet	5	0.02	1.6e-03	5.0	-5.1	2.7e-07	0.60	0.01	0.66	FALSE
7	GTEx	Brain Hypothalamus	HARS	0.14	-0.01	enet	15	-0.01	6.3e-01	4.8	5.1	2.8e-07	-0.69	0.06	0.37	FALSE
17	YFS	Blood	WDR55	0.15	0.21	bslmm	337	0.21	8.6e-67	-5.1	-5.1	2.8e-07	0.90	0.08	0.92	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	PCDHA13	0.07	0.06	blup	29	0.09	8.6e-11	4.7	5.1	2.9e-07	-0.66	0.02	0.96	FALSE