TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Forced vital capacity (FVC), Best measure
:
←
→
chr1:36,079,508-37,494,602
Best TWAS P=6.56e-08 · Best GWAS P=3.26e-07 conditioned to 1
36M
36.2M
36.4M
36.6M
36.8M
37M
37.2M
37.4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Nerve Tibial
RP11-268J15.5
0.18
0.09
lasso
5
0.08
1.5e-06
-5.1
-5.4
6.6e-08
0.96
0
1
TRUE
1
GTEx
Artery Aorta
RP11-268J15.5
0.20
0.14
lasso
4
0.13
1.2e-07
-5.1
-5.3
1.2e-07
1.00
0
1
FALSE
2
GTEx
Lung
RP11-268J15.5
0.27
0.16
lasso
4
0.15
1.6e-11
-5.1
-5.3
1.3e-07
0.98
0
1
FALSE
4
METSIM
Adipose
SH3D21
0.05
0.05
lasso
3
0.04
5.1e-07
-5.1
5.2
1.6e-07
-0.99
0
1
FALSE