Best TWAS P=6.56e-08 · Best GWAS P=3.26e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | RP11-268J15.5 | 0.20 | 0.14 | lasso | 4 | 0.13 | 1.2e-07 | -5.1 | -5.3 | 1.2e-07 | 1.00 | 0 | 1 | FALSE |
| 2 | GTEx | Lung | RP11-268J15.5 | 0.27 | 0.16 | lasso | 4 | 0.15 | 1.6e-11 | -5.1 | -5.3 | 1.3e-07 | 0.98 | 0 | 1 | FALSE |
| 3 | GTEx | Nerve Tibial | RP11-268J15.5 | 0.18 | 0.09 | lasso | 5 | 0.08 | 1.5e-06 | -5.1 | -5.4 | 6.6e-08 | 0.96 | 0 | 1 | TRUE |
| 4 | METSIM | Adipose | SH3D21 | 0.05 | 0.05 | lasso | 3 | 0.04 | 5.1e-07 | -5.1 | 5.2 | 1.6e-07 | -0.99 | 0 | 1 | FALSE |