[Hub]/) : Traits : Forced vital capacity (FVC), Best measure :

chr1:37,628,741-39,167,106

Best TWAS P=4.22e-08 · Best GWAS P=7.09e-08 conditioned to 0.0234

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta INPP5B 0.21 0.13 lasso 3 0.21 5.5e-12 -4.9 5.2 1.5e-07 -0.76 0.02 0.98 FALSE
2 GTEx Artery Aorta RP11-109P14.10 0.26 0.17 lasso 3 0.16 3.9e-09 -5.2 5.5 4.2e-08 -0.68 0.01 0.99 TRUE
3 GTEx Artery Tibial INPP5B 0.35 0.12 lasso 6 0.25 6.0e-20 2.8 5.1 2.7e-07 -0.65 0.01 0.98 FALSE
4 GTEx Artery Tibial RP11-109P14.10 0.21 0.13 lasso 6 0.15 1.7e-11 -5.2 5.4 5.4e-08 -0.67 0.01 0.99 FALSE
5 GTEx Esophagus Muscularis FHL3 0.10 0.02 enet 2 0.00 4.3e-01 3.8 5.1 3.0e-07 -0.80 0.02 0.75 FALSE
6 GTEx Esophagus Muscularis RP11-109P14.10 0.17 0.11 lasso 6 0.13 3.6e-08 -5.0 5.4 7.7e-08 -0.76 0.01 0.99 FALSE
7 GTEx Lung RP11-109P14.10 0.15 0.03 enet 14 0.12 9.2e-10 2.8 5.1 2.9e-07 -0.45 0.04 0.96 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma INPP5B 0.05 0.03 blup 68 0.05 6.7e-06 4.2 5.2 2.0e-07 -0.82 0.08 0.90 FALSE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FHL3 0.08 0.08 lasso 2 0.08 1.4e-09 -5.2 5.2 1.8e-07 -0.97 0.00 1.00 FALSE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma C1orf122 0.07 0.07 blup 32 0.05 3.8e-03 -5.0 -5.2 1.8e-07 0.75 0.00 0.80 FALSE
11 The Cancer Genome Atlas Stomach Adenocarcinoma FHL3 0.10 0.05 lasso 2 0.03 2.2e-03 -5.2 5.2 2.5e-07 -0.98 0.00 0.93 FALSE