[Hub]/) : Traits : Forced vital capacity (FVC), Best measure : ← →

chr1:25,475,418-27,595,862

Best TWAS P=8.55e-14 · Best GWAS P=1.72e-13 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Coronary	CNKSR1	0.23	0.15	lasso	7	0.13	3.2e-05	5.9	5.3	9.3e-08	0.57	0.10	0.81	TRUE
2	GTEx	Cells Transformed fibroblasts	RP1-125I3.2	0.06	0.04	enet	19	0.03	3.3e-03	6.6	-6.0	1.9e-09	-0.58	0.04	0.70	TRUE
3	GTEx	Esophagus Mucosa	DHDDS	0.11	0.06	lasso	4	0.04	6.6e-04	-6.0	-6.5	5.8e-11	-0.25	0.56	0.04	TRUE
4	GTEx	Esophagus Mucosa	CNKSR1	0.21	0.12	lasso	9	0.13	4.2e-09	5.7	5.4	6.4e-08	0.55	0.97	0.03	FALSE
5	GTEx	Esophagus Mucosa	PDIK1L	0.10	0.09	lasso	6	0.09	8.8e-07	6.9	-7.0	2.5e-12	-0.65	0.06	0.94	FALSE
6	GTEx	Nerve Tibial	PDIK1L	0.09	0.01	enet	10	0.03	2.2e-03	7.1	-7.1	1.3e-12	-0.83	0.02	0.98	FALSE
7	GTEx	Pancreas	CNKSR1	0.20	0.03	enet	20	0.04	7.3e-03	7.1	-6.3	3.7e-10	-0.67	0.04	0.68	TRUE
8	GTEx	Pituitary	CNKSR1	0.38	0.16	lasso	7	0.15	1.4e-04	5.9	-6.8	9.1e-12	-0.64	0.14	0.59	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	CNKSR1	0.15	0.10	lasso	7	0.09	1.0e-05	5.9	-7.0	2.0e-12	-0.73	0.16	0.82	FALSE
10	GTEx	Skin Not Sun Exposed Suprapubic	PDIK1L	0.22	0.05	enet	37	0.11	8.3e-07	6.9	-6.3	3.6e-10	-0.62	0.07	0.93	TRUE
11	GTEx	Skin Sun Exposed Lower leg	PDIK1L	0.14	0.05	enet	23	0.12	3.1e-10	6.9	-6.3	3.0e-10	-0.56	0.07	0.93	TRUE
12	GTEx	Thyroid	CNKSR1	0.10	0.04	lasso	7	0.03	2.1e-03	7.0	-7.3	2.4e-13	-0.77	0.02	0.97	FALSE
13	GTEx	Thyroid	SEPN1	0.10	0.03	lasso	3	0.04	7.0e-04	-3.8	-5.9	4.7e-09	-0.37	0.73	0.19	TRUE
14	GTEx	Whole Blood	CEP85	0.07	0.01	enet	17	0.02	1.3e-02	-2.8	-5.1	3.0e-07	-0.31	0.23	0.18	FALSE
15	METSIM	Adipose	RPS6KA1	0.04	0.01	bslmm	367	0.03	3.9e-05	5.9	5.4	7.3e-08	0.41	0.75	0.12	FALSE
16	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	TRIM63	0.03	0.02	blup	33	0.02	4.6e-03	6.9	7.3	3.7e-13	0.62	0.01	0.83	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	GRRP1	0.03	0.02	enet	7	0.01	3.9e-04	-3.5	-5.3	1.1e-07	-0.47	0.22	0.60	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	PDIK1L	0.02	0.01	blup	37	0.02	6.1e-05	6.9	-6.0	1.8e-09	-0.55	0.02	0.94	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	TRIM63	0.15	0.16	lasso	2	0.16	2.3e-32	6.9	6.9	5.0e-12	0.63	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	TRIM63	0.14	0.15	lasso	1	0.14	2.2e-07	6.8	6.8	8.0e-12	0.62	0.01	0.98	FALSE
21	The Cancer Genome Atlas	Colon Adenocarcinoma	TRIM63	0.08	0.10	lasso	4	0.10	3.7e-06	6.9	7.2	5.8e-13	0.62	0.01	0.99	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PDIK1L	0.02	0.02	blup	37	0.02	2.8e-03	6.9	-6.8	9.9e-12	-0.64	0.01	0.84	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC30A2	0.03	0.02	lasso	3	0.01	1.1e-02	5.3	-6.5	1.0e-10	-0.55	0.01	0.93	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TRIM63	0.11	0.11	enet	4	0.12	9.0e-14	6.9	6.3	2.4e-10	0.62	0.01	0.99	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	PDIK1L	0.03	0.01	blup	37	0.02	2.6e-03	6.9	-6.2	5.6e-10	-0.62	0.01	0.58	FALSE
26	The Cancer Genome Atlas	Brain Lower Grade Glioma	TRIM63	0.29	0.33	enet	20	0.33	2.5e-38	6.9	7.5	8.6e-14	0.59	0.01	0.99	TRUE
27	The Cancer Genome Atlas	Lung Adenocarcinoma	TRIM63	0.14	0.20	enet	7	0.21	9.4e-24	6.9	7.1	1.1e-12	0.62	0.01	0.99	TRUE
28	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CNKSR1	0.11	0.03	blup	57	0.05	3.5e-06	7.0	-5.6	2.1e-08	-0.62	0.01	0.97	FALSE
29	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PDIK1L	0.02	0.00	blup	37	0.02	1.2e-03	3.5	-6.8	1.2e-11	-0.66	0.02	0.73	FALSE
30	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TRIM63	0.16	0.11	lasso	1	0.10	2.0e-11	6.9	6.9	4.6e-12	0.63	0.01	0.99	FALSE
31	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TRIM63	0.14	0.18	lasso	7	0.15	3.0e-10	6.8	6.8	7.9e-12	0.63	0.01	0.99	FALSE
32	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	RPS6KA1	0.11	0.05	lasso	6	0.07	8.0e-04	-5.7	6.4	1.9e-10	0.21	0.01	0.87	TRUE
33	The Cancer Genome Atlas	Prostate Adenocarcinoma	PDIK1L	0.03	0.03	blup	37	0.02	7.0e-03	-3.3	-5.9	3.9e-09	-0.54	0.03	0.26	FALSE
34	The Cancer Genome Atlas	Prostate Adenocarcinoma	SH3BGRL3	0.05	0.03	lasso	2	0.03	9.3e-04	6.6	7.3	2.0e-13	0.88	0.00	0.94	TRUE
35	The Cancer Genome Atlas	Rectum Adenocarcinoma	EXTL1	0.14	0.03	blup	46	0.05	2.2e-02	3.6	-5.2	1.9e-07	-0.51	0.02	0.40	FALSE
36	The Cancer Genome Atlas	Rectum Adenocarcinoma	TRIM63	0.28	0.22	lasso	3	0.20	1.7e-05	5.3	6.2	4.3e-10	0.55	0.03	0.87	TRUE
37	The Cancer Genome Atlas	Thyroid Carcinoma	TRIM63	0.18	0.26	enet	7	0.26	3.0e-25	6.9	7.0	2.1e-12	0.62	0.01	0.99	FALSE
38	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	TRIM63	0.19	0.07	blup	33	0.14	1.3e-04	6.9	6.7	2.1e-11	0.60	0.01	0.98	FALSE