[Hub]/) : Traits : Forced vital capacity (FVC), Best measure :

chr6:80,120,201-81,763,771

Best TWAS P=3.75e-12 · Best GWAS P=3.1e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-250B2.6 0.07 0.04 lasso 4 0.05 4.4e-05 7.0 -5.6 2.5e-08 -0.92 0.01 0.98 FALSE
2 GTEx Adipose Visceral Omentum RP11-250B2.6 0.16 0.05 lasso 6 0.06 7.8e-04 3.0 -5.4 6.9e-08 -0.66 0.04 0.88 FALSE
3 GTEx Artery Aorta BCKDHB 0.14 0.14 lasso 1 0.13 9.8e-08 6.0 6.0 2.3e-09 0.90 0.43 0.57 FALSE
4 GTEx Artery Coronary BCKDHB 0.29 0.05 lasso 27 0.11 1.7e-04 6.0 5.4 6.9e-08 0.62 0.07 0.84 FALSE
5 GTEx Artery Tibial BCKDHB 0.16 0.16 lasso 11 0.15 4.9e-12 6.0 5.9 4.0e-09 0.91 0.18 0.82 FALSE
6 GTEx Cells EBV-transformed lymphocytes RP11-250B2.6 0.21 0.03 enet 37 0.13 4.7e-05 6.0 -5.3 1.4e-07 -0.57 0.04 0.73 FALSE
7 GTEx Cells Transformed fibroblasts BCKDHB 0.16 0.02 enet 42 0.04 3.7e-04 6.9 6.2 4.6e-10 0.67 0.01 0.98 FALSE
8 GTEx Colon Transverse RP11-250B2.6 0.15 0.16 lasso 2 0.13 9.8e-07 6.9 -6.8 1.4e-11 -1.00 0.00 1.00 FALSE
9 GTEx Esophagus Mucosa RP11-250B2.6 0.20 0.16 lasso 7 0.23 3.3e-15 -3.1 -5.3 1.2e-07 -0.68 0.39 0.61 FALSE
10 GTEx Esophagus Muscularis BCKDHB 0.18 0.07 enet 25 0.06 2.4e-04 6.0 6.4 1.3e-10 0.85 0.18 0.81 FALSE
11 GTEx Lung BCKDHB 0.09 0.06 enet 10 0.05 1.8e-04 6.0 6.0 2.0e-09 0.90 0.38 0.58 FALSE
12 GTEx Lung RP11-250B2.6 0.09 0.05 enet 16 0.07 5.3e-06 7.0 -6.5 6.7e-11 -0.80 0.00 1.00 FALSE
13 GTEx Nerve Tibial BCKDHB 0.18 0.11 lasso 9 0.10 2.4e-07 6.0 6.4 1.3e-10 0.92 0.05 0.95 FALSE
14 GTEx Skin Not Sun Exposed Suprapubic RP11-250B2.6 0.08 0.05 lasso 4 0.01 8.1e-02 7.0 -6.5 7.4e-11 -0.94 0.02 0.93 FALSE
15 GTEx Stomach RP11-250B2.6 0.13 0.15 lasso 6 0.12 2.5e-06 6.9 -6.8 8.5e-12 -0.99 0.00 1.00 FALSE
16 GTEx Testis RP11-250B2.6 0.09 0.05 lasso 6 0.04 6.9e-03 7.0 -6.7 2.6e-11 -0.94 0.02 0.96 FALSE
17 GTEx Thyroid BCKDHB 0.17 0.06 lasso 8 0.10 3.4e-08 7.0 6.5 6.8e-11 0.92 0.01 0.99 FALSE
18 GTEx Thyroid RP11-250B2.6 0.11 0.10 lasso 2 0.07 3.2e-06 6.9 -7.0 3.7e-12 -1.00 0.00 1.00 TRUE
19 ROSMAP Brain Pre-frontal Cortex BCKDHB 0.18 0.13 lasso 6 0.14 2.9e-17 6.0 5.6 1.9e-08 0.88 0.53 0.47 FALSE
20 The Cancer Genome Atlas Testicular Germ Cell Tumors BCKDHB 0.19 0.02 blup 137 0.06 2.6e-03 6.0 5.9 4.7e-09 0.78 0.02 0.32 FALSE