[Hub]/) : Traits : Forced vital capacity (FVC), Best measure : ← →

chr1:40,748,755-42,542,658

Best TWAS P=4.64e-29 · Best GWAS P=2.02e-21 conditioned to 0.253

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta CTPS1 0.10 0.00 enet 8 0.00 4.6e-01 6.0 6.2 4.4e-10 0.49 0.10 0.13 FALSE
2 GTEx Brain Cerebellum FOXO6 0.35 0.33 enet 21 0.36 1.2e-11 4.2 6.3 2.8e-10 0.57 0.70 0.30 FALSE
3 GTEx Breast Mammary Tissue (Female) CTPS1 0.12 -0.01 lasso 4 -0.01 7.5e-01 6.2 6.3 2.4e-10 0.41 0.04 0.06 FALSE
4 GTEx Cells EBV-transformed lymphocytes CTPS1 0.26 0.11 lasso 6 0.08 1.6e-03 7.2 6.6 3.3e-11 0.78 0.22 0.28 FALSE
5 GTEx Lung CTPS1 0.06 0.04 lasso 3 0.04 2.4e-04 6.9 7.4 1.9e-13 0.68 0.18 0.68 FALSE
6 GTEx Nerve Tibial SCMH1 0.16 0.03 enet 24 0.07 1.6e-05 9.5 -9.5 1.5e-21 -0.78 0.01 0.99 FALSE
7 GTEx Testis SLFNL1 0.30 0.17 lasso 14 0.28 5.3e-13 8.8 6.6 3.7e-11 0.24 0.16 0.84 FALSE
8 GTEx Testis CTPS1 0.57 0.28 enet 17 0.38 1.0e-17 -3.3 5.3 1.0e-07 0.50 1.00 0.00 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma SLFNL1 0.03 0.01 enet 6 0.02 5.6e-05 -1.3 5.7 1.3e-08 0.01 0.35 0.14 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma SCMH1 0.04 0.01 enet 7 0.02 2.5e-03 -1.2 -7.2 6.7e-13 -0.28 0.05 0.23 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma CTPS 0.06 0.00 enet 14 0.02 3.3e-03 -0.1 -5.4 8.0e-08 -0.08 0.03 0.05 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma SCMH1 0.03 0.03 lasso 2 0.02 6.2e-03 9.2 -9.2 4.6e-20 -0.62 0.07 0.60 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma SCMH1 0.07 0.08 blup 97 0.07 2.5e-07 9.5 -11.2 4.6e-29 -0.89 0.01 0.99 TRUE