Best TWAS P=1.15e-11 · Best GWAS P=3.16e-11 conditioned to 0.016
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CDK6 | 0.12 | 0.1 | lasso | 2 | 0.10 | 1.9e-12 | 6.2 | 6.2 | 4.5e-10 | 0.77 | 0.05 | 0.95 | FALSE |
2 | GTEx | Testis | CDK6 | 0.10 | 0.1 | lasso | 3 | 0.09 | 8.0e-05 | 6.4 | -6.8 | 1.2e-11 | -0.74 | 0.02 | 0.97 | TRUE |