Best TWAS P=2.45e-13 · Best GWAS P=3.96e-18 conditioned to 0.00047
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | CCDC126 | 0.12 | 0.03 | lasso | 7 | 0.01 | 4.3e-02 | -6.7 | 5.9 | 3.1e-09 | -0.79 | 0.01 | 0.96 | FALSE |
| 2 | YFS | Blood | CCDC126 | 0.05 | 0.04 | enet | 10 | 0.05 | 1.6e-15 | -5.7 | -5.2 | 2.0e-07 | 0.51 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Esophageal Carcinoma | TRA2A | 0.18 | 0.02 | blup | 40 | 0.05 | 1.2e-02 | -7.9 | -7.3 | 2.5e-13 | 0.74 | 0.01 | 0.48 | TRUE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | RPS2P32 | 0.08 | 0.02 | blup | 27 | 0.02 | 3.1e-02 | -4.1 | 5.3 | 1.5e-07 | -0.72 | 0.01 | 0.56 | FALSE |