TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Forced vital capacity (FVC), Best measure
:
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chr7:22,946,782-24,382,726
Best TWAS P=2.45e-13 · Best GWAS P=3.96e-18 conditioned to 0.00047
23M
23.2M
23.4M
23.6M
23.8M
24M
24.2M
24.4M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Esophageal Carcinoma
TRA2A
0.18
0.02
blup
40
0.05
1.2e-02
-7.9
-7.3
2.5e-13
0.74
0.01
0.48
TRUE
2
YFS
Blood
CCDC126
0.05
0.04
enet
10
0.05
1.6e-15
-5.7
-5.2
2.0e-07
0.51
1.00
0.00
TRUE
1
GTEx
Esophagus Mucosa
CCDC126
0.12
0.03
lasso
7
0.01
4.3e-02
-6.7
5.9
3.1e-09
-0.79
0.01
0.96
FALSE
4
The Cancer Genome Atlas
Soft Tissue Sarcoma
RPS2P32
0.08
0.02
blup
27
0.02
3.1e-02
-4.1
5.3
1.5e-07
-0.72
0.01
0.56
FALSE