Best TWAS P=1.59e-09 · Best GWAS P=7.52e-11 conditioned to 1.1e-09
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | NOV | 0.12 | 0.05 | enet | 18 | 0.04 | 3.7e-03 | -3.9 | -5.6 | 1.7e-08 | -0.05 | 0.20 | 0.08 | FALSE |
2 | GTEx | Colon Sigmoid | NOV | 0.15 | 0.16 | lasso | 4 | 0.15 | 6.6e-06 | -5.3 | -5.3 | 1.4e-07 | 0.05 | 0.46 | 0.37 | FALSE |
3 | GTEx | Lung | NOV | 0.06 | 0.02 | enet | 23 | 0.03 | 2.5e-03 | -4.7 | -5.8 | 6.1e-09 | -0.02 | 0.34 | 0.05 | FALSE |
4 | NTR | Blood | NOV | 0.02 | 0.01 | bslmm | 481 | 0.01 | 1.7e-04 | -5.4 | -6.0 | 1.6e-09 | 0.07 | 0.46 | 0.45 | TRUE |