TWAS hub - NOV

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0620	0.0220	3.9e-05	0.025	0.041	0.048	0.042	0.046	4.4e-04	7.7e-06	1.5e-06	7.3e-06	2.7e-06
2	GTEx	Artery Aorta	0.1160	0.0520	7.0e-03	0.045	NA	0.038	NA	0.028	1.6e-03	NA	3.7e-03	NA	1.1e-02
3	GTEx	Artery Tibial	0.0920	0.0367	1.8e-03	0.005	NA	0.001	NA	0.000	1.2e-01	NA	2.7e-01	NA	3.5e-01
4	GTEx	Brain Cerebellar Hemisphere	0.3750	0.0930	1.7e-04	0.097	NA	0.195	NA	0.180	1.9e-03	NA	9.9e-06	NA	2.3e-05
5	GTEx	Cells Transformed fibroblasts	0.1020	0.0350	9.9e-05	0.038	NA	0.027	NA	0.025	7.5e-04	NA	3.7e-03	NA	5.2e-03
6	GTEx	Colon Sigmoid	0.1550	0.0570	1.8e-03	0.160	NA	0.140	NA	0.148	2.7e-06	NA	1.2e-05	NA	6.7e-06
7	GTEx	Esophagus Muscularis	0.1140	0.0450	8.8e-04	0.034	NA	0.053	NA	0.039	3.7e-03	NA	3.9e-04	NA	2.1e-03
8	GTEx	Lung	0.0604	0.0262	6.3e-03	0.019	NA	0.029	NA	0.020	1.2e-02	NA	2.5e-03	NA	1.1e-02
9	GTEx	Skin Sun Exposed Lower leg	0.1140	0.0380	1.0e-04	0.028	NA	0.044	NA	0.044	2.1e-03	NA	1.4e-04	NA	1.4e-04
10	NTR	Blood	0.0221	0.0095	8.7e-04	0.014	0.010	0.003	0.010	0.009	2.3e-05	2.6e-04	2.9e-02	1.7e-04	3.7e-04
11	ROSMAP	Brain Pre-frontal Cortex	0.1017	0.0319	8.1e-07	0.017	0.064	0.059	0.067	0.062	2.5e-03	1.2e-08	4.6e-08	5.7e-09	2.2e-08
12	TCGA	Bladder Urothelial Carcinoma	0.0300	0.0200	7.9e-03	0.005	0.009	0.005	NA	0.004	1.1e-01	5.3e-02	1.0e-01	NA	1.3e-01
13	TCGA	Colon Adenocarcinoma	0.3090	0.1150	3.0e-06	0.101	0.105	0.099	NA	0.104	1.8e-06	1.2e-06	2.4e-06	NA	1.4e-06
14	TCGA	Kidney Renal Clear Cell Carcinoma	0.0617	0.0322	5.3e-04	0.001	0.027	0.017	NA	0.008	2.1e-01	4.3e-04	4.5e-03	NA	4.1e-02
15	TCGA	Brain Lower Grade Glioma	0.1506	0.0617	4.3e-05	0.007	0.039	0.044	NA	0.029	4.3e-02	2.7e-05	8.0e-06	NA	3.0e-04
16	TCGA	Pancreatic Adenocarcinoma	0.1070	0.0840	6.7e-03	0.018	0.043	0.053	NA	0.031	5.6e-02	6.9e-03	2.9e-03	NA	1.9e-02
17	TCGA	Prostate Adenocarcinoma	0.0440	0.0221	1.3e-05	0.047	0.048	0.035	NA	0.039	1.2e-05	8.7e-06	1.4e-04	NA	5.2e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Diastolic blood pressure, automated reading	14.7	45.5	73.4	-6.5	-7.4	-5.6	-3.7	-6.1	-8.6	-6.6	-7.2	-8.1	-7.1	5.2	-8.2	-7.5	-5.2	-4.3	-6.9	-7.9
Systolic Blood Pressure	8.5	42.6	73.4	7.4	8.2	3.7	0.8	3.1	8.2	7.6	7.8	7.8	8.6	-4.9	8.2	5.6	4.3	1.1	7.9	7.4
Systolic blood pressure, automated reading	8.1	23.6	45.8	5.3	6.6	2.9	0.2	1.8	6.0	5.2	5.7	5.6	6.8	-3.5	6.0	4.6	3.4	0.3	5.5	5.8
Standing height	6.9	68.5	105.5	-8.0	-9.9	-6.8	-3.4	-9.3	-10.2	-7.3	-10.3	-9.0	-9.5	6.1	-9.9	-8.4	-5.8	-3.9	-9.1	-9.4
Sitting height	6.6	46.8	82.8	-7.4	-7.2	-5.5	-5.6	-9.1	-8.1	-5.5	-7.6	-7.0	-9.1	5.6	-7.9	-5.7	-4.1	-2.5	-7.6	-7.1
Trunk fat-free mass	6.6	37.7	65.4	-5.9	-7.5	-4.3	-2.7	-5.5	-7.9	-5.2	-7.0	-6.9	-7.0	4.1	-7.9	-6.8	-3.2	-2.9	-8.1	-6.9
Trunk predicted mass	6.6	37.9	65.2	-6.0	-7.5	-4.2	-2.7	-5.6	-7.9	-5.2	-7.0	-7.0	-7.0	4.1	-7.9	-6.9	-3.3	-3.1	-8.1	-6.9
Comparative height size at age 10	6.3	34.9	64.8	-5.7	-6.8	-4.7	-2.8	-6.2	-7.4	-5.5	-8.1	-6.4	-5.8	3.8	-6.9	-6.3	-4.8	-2.4	-6.6	-7.0
Whole body fat-free mass	6.1	34.7	61.5	-5.8	-6.9	-3.8	-2.5	-5.5	-7.7	-5.0	-6.3	-6.8	-6.4	3.9	-7.8	-6.7	-2.8	-3.1	-7.8	-6.7
Whole body water mass	6.0	34.3	60.8	-5.7	-6.9	-3.8	-2.4	-5.4	-7.7	-5.0	-6.2	-6.8	-6.3	3.9	-7.7	-6.7	-2.9	-3.2	-7.8	-6.7
Forced vital capacity (FVC)	5.8	22.3	41.0	-5.0	-6.2	-4.2	0.2	-4.9	-5.7	-5.0	-5.8	-5.1	-6.4	2.3	-5.2	-4.4	-3.8	-2.4	-4.1	-5.3
Height	5.7	110.1	171.6	-9.7	-11.5	-9.2	-3.2	-13.1	-13.1	-9.2	-12.7	-11.6	-12.1	8.1	-12.4	-10.3	-8.3	-6.1	-10.7	-11.6
Arm predicted mass (right)	5.7	29.2	54.5	-5.6	-6.4	-3.3	-2.0	-4.6	-7.2	-4.8	-5.5	-6.2	-6.0	3.6	-7.2	-6.1	-2.6	-2.8	-7.4	-6.1
Arm fat-free mass (left)	5.7	28.9	51.8	-5.4	-6.2	-3.5	-2.4	-5.2	-7.2	-4.6	-5.6	-6.2	-5.4	3.3	-7.1	-6.1	-3.0	-3.2	-7.1	-6.2
Arm fat-free mass (right)	5.6	28.8	51.7	-5.3	-6.3	-3.3	-1.9	-4.9	-7.2	-4.6	-5.4	-6.2	-5.9	3.5	-7.2	-6.1	-2.8	-3.2	-7.1	-6.2
Forced expiratory volume in 1-second (FEV1), predicted	5.4	11.2	24.8	-3.9	-4.2	-2.5	-1.3	-4.3	-3.9	-3.4	-5.0	-2.9	-3.6	1.8	-3.5	-3.0	-2.8	-1.1	-3.5	-3.5
Arm predicted mass (left)	5.4	27.4	48.9	-5.2	-6.1	-3.5	-2.5	-4.9	-7.0	-4.4	-5.5	-6.0	-5.4	3.2	-6.9	-5.9	-2.8	-3.3	-6.9	-6.0
Forced vital capacity (FVC), Best measure	5.1	18.8	36.4	-4.1	-5.6	-2.9	-0.5	-5.0	-5.3	-4.1	-5.8	-4.9	-6.0	1.4	-4.8	-3.9	-3.8	-2.9	-3.9	-4.5
Leg predicted mass (right)	4.9	26.0	48.7	-5.1	-5.7	-3.0	-1.9	-4.9	-6.8	-4.4	-5.0	-6.2	-5.4	3.5	-7.0	-6.0	-2.0	-2.9	-6.8	-5.9
Basal metabolic rate	4.9	27.1	48.3	-5.1	-6.1	-3.3	-2.1	-5.0	-6.9	-4.4	-5.7	-6.1	-5.3	3.4	-6.9	-6.0	-2.4	-2.9	-7.0	-5.9
Leg fat-free mass (left)	4.8	25.2	46.4	-5.3	-5.5	-2.7	-2.0	-4.9	-6.7	-4.6	-5.2	-6.0	-5.0	3.4	-6.7	-5.7	-2.1	-2.7	-6.8	-5.8
Leg fat-free mass (right)	4.8	25.5	47.2	-5.0	-5.7	-3.1	-1.9	-4.8	-6.7	-4.4	-5.0	-6.1	-5.4	3.4	-6.9	-5.9	-2.0	-2.8	-6.7	-5.8
Leg predicted mass (left)	4.7	24.9	45.8	-5.2	-5.4	-2.7	-1.9	-4.9	-6.7	-4.5	-5.2	-5.9	-5.0	3.3	-6.7	-5.7	-2.1	-2.8	-6.8	-5.7
Diverticular disease/diverticulitis (self-reported)	4.2	4.9	9.7	-2.6	-2.1	-2.0	-0.5	-2.2	-2.8	-1.7	-3.0	-2.1	-2.4	3.1	-2.4	-1.4	-2.5	-0.5	-1.8	-2.5
Medication: Atorvastatin	4.0	5.0	14.6	2.4	2.3	1.4	3.2	2.6	2.3	2.5	3.8	2.2	1.0	-1.0	2.2	1.9	1.8	0.6	2.4	1.9
Migraine (self-reported)	3.5	4.3	10.9	-1.8	-2.2	-1.0	-0.8	-1.7	-2.5	-2.0	-1.3	-3.0	-3.3	2.7	-2.7	-2.1	-0.5	-0.9	-2.1	-2.2
Pain type(s) experienced in last month: Hip pain	3.5	4.4	22.6	-0.2	1.0	0.9	4.8	2.9	1.5	0.7	3.3	1.4	2.2	-1.3	1.1	2.4	2.1	1.6	0.7	2.1
Alcohol usually taken with meals	3.3	5.3	12.1	2.7	1.8	1.1	1.9	2.6	2.5	3.5	2.5	2.6	3.2	-1.9	2.1	2.0	2.2	0.5	1.9	2.6
Falls in the last year	3.2	4.3	9.4	-2.6	-2.3	-1.5	-1.3	-1.0	-2.4	-3.0	-1.9	-3.1	-2.0	1.3	-2.8	-1.8	0.2	0.2	-2.9	-1.9
Illness, injury, bereavement, stress in last 2 years	3.1	3.8	6.4	1.9	1.9	2.2	0.9	1.8	2.3	2.5	2.2	2.5	1.8	-2.1	2.4	1.9	0.8	0.6	2.4	1.7
Forced expiratory volume in 1-second (FEV1)	3.0	10.1	22.8	-3.4	-4.8	-2.8	0.6	-3.2	-3.8	-3.1	-4.0	-3.7	-4.4	1.5	-3.7	-2.5	-1.7	-1.5	-2.8	-3.3
Number of full brothers	2.7	3.4	9.4	-2.2	-2.4	-0.7	-0.4	-0.4	-1.4	-3.1	-2.3	-1.7	-1.2	2.5	-2.0	-1.6	0.7	1.9	-2.3	-1.6
Friendships satisfaction	2.7	3.3	6.2	-1.9	-2.3	-1.5	-0.1	-1.7	-1.9	-1.9	-2.5	-1.7	-2.2	2.1	-1.6	-1.9	-1.8	-0.1	-2.2	-1.7
Average weekly spirits intake	2.6	3.2	7.2	-1.7	-0.7	-0.6	-0.8	-2.0	-2.7	-0.7	-0.7	-1.9	-2.4	1.5	-1.9	-2.1	-2.6	-1.5	-1.6	-2.6
Happiness	2.6	3.2	6.7	-1.8	-2.4	-1.4	-0.5	-1.0	-1.5	-2.4	-2.6	-1.3	-1.9	2.6	-1.6	-1.5	-0.8	1.4	-1.8	-1.9
Serious illness, injury or assault to yourself	2.5	3.1	6.9	-2.0	-2.0	-1.6	-1.0	-1.1	-2.0	-2.2	-1.2	-2.4	-1.3	1.7	-2.6	-1.6	0.3	-0.8	-2.4	-1.7
Bipolar Disorder (2011)	2.4	2.3	5.1	1.6	0.8	-0.3	0.1	1.6	1.9	1.2	1.7	1.3	1.4	-2.1	1.8	2.3	0.8	0.2	1.8	2.3
Lung FEV1/FVC ratio	2.4	12.1	25.7	4.2	3.9	2.9	0.4	3.4	4.0	4.3	3.3	3.9	5.1	-2.6	3.5	3.1	3.1	1.1	3.9	3.4
Average weekly fortified wine intake	2.4	2.8	6.1	-1.8	-1.7	-0.6	-1.5	0.0	-1.7	-2.5	-1.4	-2.2	-0.5	1.7	-2.1	-2.2	-0.4	-0.3	-2.4	-2.2
Heel bone mineral density (BMD) T-score, automated (left)	2.3	5.2	13.7	-3.7	-2.0	-0.9	-0.3	-2.2	-1.8	-3.4	-2.9	-2.3	-3.5	1.9	-2.0	-0.5	-0.6	2.0	-2.6	-2.2
Birth weight	2.3	5.0	15.6	-1.6	-1.0	-1.3	-2.2	-2.1	-2.7	-1.5	-1.4	-2.4	-3.9	0.2	-2.4	-3.0	-2.1	-2.3	-2.3	-2.7
Crohns Disease (2012)	2.2	3.5	8.5	-2.1	-2.9	-0.5	1.2	-1.5	-2.4	-2.1	-1.3	-2.8	-0.9	0.4	-2.5	-1.2	-1.3	-2.3	-2.2	-1.5
Tinnitus: Yes, but not now, but have in the past	2.2	2.3	7.8	0.7	1.8	0.9	2.5	2.2	1.4	0.5	2.8	1.5	-0.6	-1.7	1.5	1.3	0.6	1.3	1.0	1.1
Headache pain in last month	2.2	3.8	11.8	-2.4	-2.2	-1.6	0.3	-1.2	-2.1	-2.0	-1.1	-1.6	-3.4	2.7	-1.9	-1.8	-1.8	0.4	-1.7	-2.4
Qualifications: nursing, teaching	2.2	3.4	8.8	2.5	1.3	0.3	1.5	2.5	2.1	2.6	1.4	2.2	3.0	-0.8	2.1	1.0	0.5	-0.3	2.0	1.9
Relative age voice broke	2.1	3.2	10.4	2.0	1.9	2.6	1.7	1.7	1.7	1.1	3.2	1.6	1.2	-1.1	1.6	1.3	1.6	-0.1	1.9	1.8
Stomach or abdominal pain in last month	2.1	2.6	7.0	-2.2	-1.6	-1.4	0.9	-1.0	-2.0	-2.7	-1.1	-1.9	-2.5	1.2	-1.7	-1.0	-0.8	0.1	-1.9	-1.2
Financial difficulties in last 2 years	2.1	2.8	6.9	-1.7	-1.6	-2.6	-1.1	-1.8	-1.9	-1.8	-2.2	-1.8	-1.7	1.5	-1.5	-1.3	-1.2	0.3	-1.9	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	2.1	6.7	14.3	-2.3	-3.6	-1.4	0.0	-3.3	-3.2	-2.0	-3.8	-2.9	-3.8	0.5	-2.9	-1.9	-2.2	-1.8	-2.2	-2.5
Eye problems/disorders: None of the above	2.1	2.4	6.9	-1.2	-1.0	-0.4	1.4	-1.3	-2.2	-1.2	-1.2	-1.2	-0.9	0.3	-1.6	-2.3	-2.6	-2.6	-1.0	-1.4
Illnesses of father: High blood pressure	2.1	2.5	6.4	-0.7	-1.5	-2.5	-0.5	-1.9	-1.8	-0.2	-1.4	-1.4	-1.8	2.0	-1.6	-2.3	-1.3	-1.2	-1.1	-1.9
Ever smoked	2.1	3.7	6.4	-2.4	-2.1	-1.9	0.3	-0.9	-2.1	-1.9	-2.0	-1.7	-2.5	2.5	-2.0	-1.7	-1.5	1.2	-2.5	-2.1
Ever unenthusiastic/disinterested for a whole week	2.0	2.4	6.0	-2.4	-2.0	-0.9	0.5	-1.2	-1.4	-2.5	-2.1	-1.1	-1.1	2.1	-1.6	-1.0	-0.1	0.9	-2.0	-1.3
Mouth/teeth dental problems: Bleeding gums	2.0	2.6	6.2	-2.5	-1.3	-0.5	0.7	-1.4	-2.1	-2.4	-1.6	-1.7	-0.4	0.8	-2.0	-1.8	-1.3	-0.2	-1.9	-2.3
Neck or shoulder pain in last month	2.0	2.9	7.5	-1.9	-1.2	-0.4	-2.5	-2.1	-2.0	-1.5	-1.1	-2.1	-2.7	0.9	-1.7	-1.2	-1.5	-0.5	-1.9	-1.6
Medication: Lisinopril	2.0	2.6	4.9	-1.9	-1.3	-1.5	-0.7	-0.8	-1.8	-2.1	-1.5	-2.0	-2.2	1.4	-1.6	-1.1	-1.9	-1.0	-1.6	-1.7
Leg fat percentage (left)	2.0	7.1	27.1	2.2	3.8	1.9	1.5	1.2	2.4	2.8	2.9	3.1	5.2	-2.5	2.7	2.6	1.5	-0.1	2.5	2.6
Major Depression (MDD)	1.9	2.3	5.9	2.4	1.5	0.4	0.2	2.1	1.7	1.8	1.3	1.3	0.7	-1.5	1.6	1.5	0.9	-0.3	2.3	1.7
Verbal and Numeric Reasoning (VNR)	1.9	4.6	14.9	1.8	2.5	1.2	1.3	2.0	2.2	2.6	3.2	2.4	3.9	-1.9	1.9	1.2	1.8	-0.9	1.7	2.0
Health satisfaction	1.9	2.5	6.0	-1.2	-1.7	-1.6	-0.2	-1.5	-1.6	-1.2	-1.8	-1.9	-2.4	1.7	-1.7	-1.8	-0.9	-0.5	-2.0	-1.3
Qualifications: CSEs or equivalent	1.8	2.3	7.7	-1.1	-2.0	-0.8	-1.4	-0.9	-1.6	-1.0	-2.5	-1.0	-2.8	0.3	-0.9	-1.2	-2.7	-0.8	-0.7	-1.4
Frequency of tiredness / lethargy in last 2 weeks	1.8	2.9	7.9	-1.2	-2.3	-1.8	-0.0	-0.5	-1.4	-2.1	-1.4	-2.2	-2.7	2.8	-1.7	-1.1	0.5	0.8	-2.1	-0.8
Alzheimer’s Disease (in mother)	1.7	2.0	5.2	-1.4	-1.9	-1.2	0.2	0.1	-1.2	-2.0	-1.9	-1.6	-1.6	2.3	-1.5	-0.9	0.3	1.1	-1.2	-1.2
Primary Biliary Cirrhosis	1.7	2.4	5.9	1.1	1.5	-0.5	-0.6	1.7	2.3	1.1	0.6	1.9	1.0	-0.2	2.3	2.3	1.4	1.4	1.4	2.4
Lung FVC	1.7	8.5	25.5	-3.2	-3.9	-1.1	1.0	-2.8	-3.7	-2.8	-2.1	-3.3	-5.1	0.4	-3.3	-2.6	-2.6	-1.9	-3.2	-3.0
Frequency of tenseness / restlessness in last 2 weeks	1.7	2.7	9.0	-1.9	-1.5	-1.8	-0.5	0.0	-1.2	-1.5	-1.7	-1.3	-2.0	3.0	-1.7	-0.6	0.7	1.9	-2.6	-0.8
Time employed in main current job	1.7	2.0	5.8	-1.1	-1.2	0.0	-0.6	-2.2	-1.7	-1.1	-1.4	-1.2	-1.7	0.7	-1.1	-1.5	-2.4	-1.5	-0.1	-1.8
Medication: Lansoprazole	1.7	1.9	5.1	0.9	2.0	2.3	2.0	2.1	1.2	0.7	1.6	1.5	0.6	-1.8	1.3	0.3	-0.0	0.9	0.9	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	2.0	4.9	-1.5	-1.7	-0.8	1.2	-0.1	-2.1	-1.5	-1.4	-1.9	-1.0	1.2	-2.2	-1.3	-0.7	-0.2	-1.4	-1.8
Wears glasses or contact lenses	1.7	1.9	4.4	1.7	1.8	1.8	0.3	1.2	1.7	1.2	1.4	1.3	2.1	-1.2	1.5	1.1	1.1	0.2	1.2	1.5
Cholesterol lowering medication	1.7	2.5	6.1	1.7	1.7	1.4	1.7	0.9	1.6	1.5	2.5	1.2	2.0	-1.5	1.3	1.5	1.7	0.4	1.8	1.3
Blood Platelet Count	1.6	18.4	37.2	3.9	4.2	2.2	1.9	5.8	5.6	3.6	4.2	4.2	3.6	-2.1	4.4	4.9	6.1	3.6	4.0	5.5
Had other major operations	1.6	2.0	5.9	1.2	1.4	-0.7	-0.1	1.1	1.8	1.1	1.8	1.0	1.9	-0.6	1.2	1.9	2.4	0.8	1.4	1.7
Weight	1.6	8.0	16.4	-2.8	-2.8	-1.6	-1.0	-3.4	-4.1	-2.0	-3.2	-3.2	-1.6	1.5	-4.0	-3.2	-1.0	-2.3	-4.0	-3.2
Financial situation satisfaction	1.6	2.0	5.5	-2.3	-1.0	-1.2	0.0	-0.2	-1.1	-2.1	-1.1	-1.2	-1.6	1.1	-1.3	-0.8	0.5	2.1	-2.3	-1.3
HDL Cholesterol	1.5	2.6	7.1	2.5	1.3	-0.3	1.1	2.0	1.9	2.7	0.9	1.9	0.9	-1.3	1.5	1.0	1.7	0.9	1.9	1.5
Leg fat percentage (right)	1.5	5.5	25.0	1.4	3.4	1.8	1.5	1.0	2.1	1.9	2.3	2.9	5.0	-2.2	2.5	2.5	1.0	0.1	2.0	2.3
Had major operations	1.5	1.7	7.8	1.0	0.6	1.1	2.8	2.5	0.7	1.0	1.8	0.7	0.3	-2.2	0.6	0.4	1.2	0.1	0.3	1.0
Back pain experienced in last month	1.5	2.2	5.2	-1.7	-2.2	-1.5	-1.2	-1.2	-1.4	-1.6	-1.6	-2.3	-1.9	0.2	-1.9	-1.2	0.4	-0.1	-1.7	-0.9
Pain experienced in last month	1.5	2.5	7.4	2.4	1.4	0.8	-0.4	0.5	1.9	2.3	0.1	2.2	2.7	-1.0	2.0	0.9	0.6	0.2	1.7	1.6
LDL Cholesterol	1.4	2.3	6.8	-1.0	-1.6	-1.7	-0.4	-0.7	-1.4	-0.9	-1.8	-1.4	-2.1	2.6	-1.5	-1.9	-1.4	0.1	-1.0	-2.1
Chronotype (morning person)	1.4	3.2	8.7	2.3	2.1	2.1	-2.4	0.9	1.7	2.9	0.8	1.8	2.0	-1.8	1.9	0.3	0.8	-0.3	1.8	1.7
Relative age of first facial hair	1.4	2.9	7.8	1.8	2.8	2.4	1.3	1.6	1.8	1.6	2.3	1.9	1.4	-0.3	1.9	1.1	1.4	0.3	1.6	1.7
Past tobacco smoking	1.4	2.5	5.9	2.2	1.5	1.4	-1.0	0.4	1.9	1.5	1.1	1.1	2.0	-2.4	1.8	1.2	1.3	-0.6	2.3	1.6
Tense / ‘highly strung’	1.4	2.3	7.3	-1.6	-0.8	-1.9	-1.4	-0.5	-1.4	-1.5	-1.1	-1.9	-2.1	2.7	-1.8	-0.9	0.6	0.4	-1.9	-0.9
Supplements: Vitamin C	1.4	1.6	4.1	-0.7	-1.3	-0.3	-1.4	-0.8	-1.2	-1.5	-1.2	-2.0	-2.0	1.1	-1.7	-1.1	0.5	-0.5	-1.6	-0.9
Arm fat percentage (left)	1.4	5.4	19.1	2.2	3.3	2.0	1.4	0.9	2.1	2.4	2.5	2.3	4.4	-2.4	2.2	2.2	1.9	-0.3	2.4	2.2
Impedance of leg (left)	1.3	6.4	19.2	2.6	2.8	0.5	1.6	1.0	3.0	2.7	1.2	3.5	2.9	-1.9	3.6	2.9	-0.8	1.1	4.4	2.3
Hair/balding pattern: Pattern 2	1.3	1.7	4.5	-1.4	-1.9	1.3	2.1	0.6	-1.3	-1.9	-0.2	-2.1	-0.8	-0.0	-1.5	-0.7	-0.3	-0.4	-1.5	-0.8
Arm fat percentage (right)	1.3	5.2	21.0	2.1	3.2	1.8	1.0	0.5	2.0	2.3	2.3	2.3	4.6	-2.4	2.2	2.1	1.7	-0.4	2.3	2.0
Breastfed as a baby	1.3	1.6	4.0	-1.5	-0.2	0.6	0.5	-1.9	-1.6	-1.4	-0.4	-1.5	-2.0	0.9	-1.4	-1.2	-1.0	-1.1	-1.2	-1.5
Birth weight of first child	1.3	2.4	7.9	-0.9	-1.1	-0.6	-0.2	-1.4	-2.6	-1.1	-0.8	-1.5	-2.2	-0.7	-2.2	-1.3	-1.9	-2.8	-0.9	-1.5
Medication: Ibuprofen	1.3	1.5	3.8	-1.9	-0.5	-0.8	-0.6	-1.4	-1.2	-1.7	-1.6	-1.1	-1.0	1.9	-1.3	-1.0	0.1	0.7	-1.3	-1.3
Overall health rating	1.3	2.8	9.7	-1.1	-1.0	-0.6	-1.3	-1.5	-1.3	-2.1	-1.3	-2.4	-3.1	1.9	-1.8	-1.8	0.6	0.6	-2.1	-1.6
Tinnitus: Yes, now most or all of the time	1.3	1.5	9.2	-0.2	-2.3	-3.0	0.2	-1.0	-0.3	-0.1	-1.9	-0.5	-1.3	1.4	-0.1	-0.2	-1.2	-0.0	0.6	-0.6
Medication: Paracetamol	1.3	2.0	4.8	-2.2	-1.3	-0.5	-0.5	-1.9	-1.0	-1.7	-0.9	-1.6	-2.0	2.1	-1.5	-0.3	0.7	1.2	-1.7	-1.1
Allergy or Eczema	1.2	3.1	10.0	1.5	1.3	1.5	1.0	0.9	1.8	1.2	2.6	2.1	3.2	-2.3	2.0	1.2	0.6	-0.8	1.6	2.1
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	8.6	-2.5	-1.3	-0.9	-0.3	-1.8	-1.1	-2.0	-2.1	-1.1	-2.9	1.3	-1.2	-0.3	-0.6	2.2	-1.7	-1.8
Medication: Amlodipine	1.2	1.7	4.5	1.1	1.7	0.1	1.1	0.2	1.5	2.1	2.1	1.4	1.9	-0.3	1.5	1.3	0.8	0.6	0.9	1.4
Medication: Allopurinol	1.2	1.6	3.8	1.1	1.9	1.5	1.3	0.8	1.1	1.6	1.2	1.9	1.5	-1.4	1.4	0.7	0.2	-0.1	1.3	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	4.6	-0.7	1.2	0.6	1.9	0.0	1.2	0.1	2.1	1.3	1.2	-0.7	1.3	1.8	0.2	0.6	0.5	1.6
Smoking status: Previous	1.2	1.7	4.8	-2.0	-1.3	-1.1	1.5	0.0	-1.4	-1.3	-0.5	-1.0	-1.4	2.1	-1.6	-0.6	-0.2	0.9	-2.2	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	2.4	0.8	1.2	1.4	0.1	1.6	1.0	0.9	1.0	1.3	1.2	-1.2	0.8	1.5	1.4	0.1	0.6	1.4
Impedance of whole body	1.2	6.3	20.8	2.6	3.1	0.8	1.2	0.3	3.2	2.2	1.3	3.1	3.1	-1.5	3.5	3.1	-0.0	1.1	4.6	2.4
Body fat percentage	1.1	4.5	20.8	1.6	3.4	1.7	1.6	0.3	1.6	2.0	2.2	2.1	4.6	-2.0	1.8	2.0	1.4	-0.6	2.1	1.7
Pulse wave peak to peak time	1.1	1.3	5.6	-1.9	-0.4	-0.8	-2.4	-1.6	-1.0	-1.4	-1.0	-0.7	-0.1	-0.0	-0.8	-0.7	-1.1	0.4	-0.9	-1.1
Medication: Omeprazole	1.1	1.3	3.9	-1.2	-1.1	0.3	0.9	0.7	-0.6	-1.3	0.7	-1.1	0.4	1.1	-1.3	-0.0	2.0	1.8	-1.9	-0.2
Commuting to job workplace: Public transport	1.1	1.4	3.2	1.4	1.5	0.1	1.4	1.0	1.1	1.2	1.8	1.3	1.7	-1.4	1.3	0.1	0.3	-0.5	0.8	1.0
Supplements: Calcium	1.1	1.2	3.6	-0.4	-1.6	-1.0	0.9	1.1	-0.5	-0.9	-1.9	-0.3	-1.4	1.5	-0.6	-0.4	-0.1	1.8	-1.1	-0.7
Diabetes (father)	1.0	1.3	5.4	-0.7	0.6	-0.0	-2.3	-2.2	-0.8	-0.5	-1.5	-0.5	-0.7	0.6	-0.5	-1.5	-0.9	-0.1	-0.9	-1.3
Impedance of leg (right)	1.0	5.1	14.8	1.7	2.5	0.5	1.5	0.8	2.7	1.7	0.4	3.3	2.9	-1.4	3.4	2.9	-1.3	1.4	3.9	2.0
Mouth/teeth dental problems	1.0	1.5	3.5	1.4	0.7	-0.3	-0.8	0.3	1.7	1.9	0.4	1.7	1.3	-0.6	1.7	1.3	0.7	0.2	1.9	1.6
Diabetes (self-reported)	1.0	1.5	5.5	2.3	0.9	0.2	-1.2	-1.9	0.9	2.2	0.4	1.0	0.8	-1.5	1.2	0.0	-0.2	-0.8	1.5	0.5
Illnesses of mother	1.0	1.2	4.1	0.0	0.4	1.4	1.6	1.9	0.8	-0.2	0.5	0.6	0.3	-0.6	0.3	1.1	2.0	1.9	-0.3	1.1
Medication: Paracetamol	1.0	1.7	4.8	-2.2	-1.2	-0.9	-0.7	-1.6	-0.7	-1.3	-0.8	-1.1	-1.9	2.1	-1.1	0.3	0.7	1.7	-1.5	-0.6
Gout (self-reported)	1.0	1.4	3.8	0.9	2.0	1.4	0.8	0.2	1.0	1.5	1.1	1.9	1.1	-1.0	1.5	1.1	-0.3	-0.3	1.3	1.3
Osteoarthritis (self-reported)	1.0	1.3	3.7	-0.1	-0.9	0.9	-1.6	-0.0	-1.0	-0.9	0.7	-1.2	-1.2	-1.8	-0.7	-1.7	-1.4	-1.9	-0.5	-1.0
Number of self-reported non-cancer illnesses	1.0	1.7	4.1	-1.2	-1.7	-0.8	-0.5	-1.6	-1.3	-1.3	-1.1	-2.0	-2.0	1.4	-1.7	-0.7	0.5	0.0	-1.2	-1.0
Basal cell carcinoma (self-reported)	1.0	1.2	6.7	-1.8	-0.8	0.0	2.6	0.7	-0.7	-1.9	0.5	-1.0	-1.1	0.6	-0.9	-0.1	-0.2	0.3	-1.3	-0.5
Bipolar Disorder (2018)	0.9	1.4	2.8	1.2	-0.2	-0.6	1.3	1.6	1.4	0.7	0.9	0.7	1.4	-1.1	1.3	1.7	0.7	1.0	1.7	1.4
Crohns Disease (2017)	0.9	1.9	4.5	-1.9	-2.0	0.7	2.1	-0.8	-1.6	-2.0	-1.0	-1.8	0.2	-0.4	-1.6	0.2	-1.1	-1.1	-1.6	-0.8
Irritable Bowel Disease (IBD)	0.9	2.2	8.6	-2.5	-2.1	0.1	2.1	-0.7	-1.3	-2.9	-1.1	-1.9	-0.0	0.8	-1.3	0.3	-1.1	0.1	-1.7	-0.9
Lupus	0.9	1.4	4.1	1.5	1.0	1.0	2.0	0.5	0.8	1.2	1.1	1.5	1.5	-1.7	1.2	0.7	-0.6	0.5	1.4	0.1
Heel T-Score	0.9	7.3	27.5	-4.3	-2.9	-2.8	2.1	-2.3	-2.0	-2.4	-1.8	-1.5	-5.2	3.1	-2.0	-0.3	-0.8	3.3	-2.2	-2.5
Trunk fat percentage	0.9	3.4	16.9	1.4	3.2	1.4	1.3	-0.3	1.2	1.7	1.8	1.6	4.1	-1.6	1.3	1.6	1.4	-0.9	1.9	1.3
Medication: Levothyroxine sodium	0.9	1.5	2.9	-1.2	0.1	-0.7	-1.6	-1.5	-1.4	-1.2	-1.6	-0.7	-1.3	1.7	-1.3	-1.3	-0.6	-0.2	-1.2	-1.4
Fluid intelligence score	0.9	1.9	8.9	1.3	1.1	0.1	0.4	1.6	1.6	1.6	1.6	1.9	3.0	-0.9	1.6	0.5	0.5	0.0	1.2	1.1
Impedance of arm (right)	0.9	4.0	13.4	2.2	2.3	0.6	0.7	-0.1	2.7	1.6	0.4	2.3	2.9	-1.2	2.8	2.4	0.3	1.1	3.7	1.9
Impedance of arm (left)	0.9	4.0	15.2	2.3	2.5	0.6	1.3	0.2	2.6	1.7	0.7	2.1	2.5	-0.9	2.7	2.4	0.3	0.8	3.9	1.9
Ever highly irritable/argumentative for 2 days	0.9	1.1	3.3	-1.2	-0.8	0.4	-1.1	1.1	-0.5	-1.2	-0.6	-1.1	-1.3	0.3	-1.1	-0.8	1.8	1.0	-1.4	-0.4
Mouth/teeth dental problems: Loose teeth	0.9	1.1	2.9	-1.3	-0.5	-1.7	-0.5	-1.1	-1.0	-0.7	0.1	-1.6	-1.3	1.4	-1.3	0.4	0.5	-0.1	-1.4	-0.2
Chest pain or discomfort	0.9	1.2	3.2	-0.6	-1.7	0.3	-1.1	-0.6	-1.4	-1.7	-1.8	-1.0	-1.4	-0.4	-1.2	-1.0	-0.6	-0.4	-0.9	-1.0
Handedness (chirality/laterality): Left-handed	0.9	1.1	3.4	-0.1	-1.7	-0.0	-0.8	-1.8	-1.2	0.2	-1.1	-0.7	-1.2	-0.5	-0.7	-0.9	-1.9	-0.7	-0.3	-1.3
Medication for cholesterol	0.9	1.4	4.2	-1.0	-2.0	-1.0	-1.4	0.4	-0.4	-1.6	-2.0	-0.4	-0.8	1.5	-0.5	-0.5	-0.2	1.8	-0.9	-0.9
Irritability	0.9	1.6	5.6	-1.7	-1.8	-2.1	0.4	-0.7	-0.8	-2.4	-0.8	-1.2	-1.9	1.5	-0.7	-0.3	-0.2	0.1	-0.7	-0.2
Ever had prostate specific antigen (PSA) test	0.9	1.0	2.4	0.3	1.6	0.1	1.1	1.0	1.1	1.0	1.1	1.4	0.3	0.4	1.2	1.3	0.5	1.2	0.9	1.0
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	3.0	-1.4	-0.7	-0.2	1.0	-0.0	-0.7	-1.6	0.4	-1.0	0.0	0.9	-1.2	0.3	1.4	1.7	-1.7	-0.4
Alzheimer’s Disease (in father)	0.8	0.9	5.9	1.4	0.6	1.6	-2.4	-0.5	0.6	1.1	0.2	0.8	-0.3	-1.0	0.5	0.1	0.5	-0.4	0.6	0.3
Smoking Status	0.8	1.9	4.8	-2.2	-0.8	-1.1	0.9	-1.0	-1.1	-1.6	-1.6	-0.7	-1.7	1.8	-0.8	-0.1	-1.2	2.1	-1.2	-1.3
Type 2 Diabetes (T2D) (2018)	0.8	1.5	5.6	2.4	0.9	0.3	-0.1	-0.8	1.4	1.9	0.2	1.4	1.0	-0.6	1.5	0.9	0.8	0.9	2.2	0.9
Medication for hormone replacement therapy	0.8	0.9	3.0	0.8	1.7	-0.5	1.0	1.2	0.8	0.2	1.2	0.5	-0.0	-0.7	0.5	0.1	0.8	-1.6	-0.1	1.4
Medication: Metformin	0.8	1.1	3.0	1.6	0.4	-0.1	-1.4	-1.5	1.0	1.7	-0.0	0.6	1.2	-0.5	1.0	0.8	0.5	0.1	1.7	0.8
Diabetes (mother)	0.8	1.0	2.6	1.6	1.1	0.9	-1.1	-1.0	0.9	1.0	0.2	1.1	1.2	-0.8	1.4	0.1	-0.5	-0.6	1.6	0.6
Bilateral oophorectomy (both ovaries removed)	0.8	1.0	3.0	1.0	1.7	0.3	0.6	-0.1	1.0	1.5	1.1	1.0	1.4	-0.4	1.2	0.8	-0.2	0.0	1.3	0.6
Lung cancer (father)	0.8	0.9	1.8	-0.9	-1.1	-0.1	-1.2	-0.5	-0.9	-1.3	-1.4	-1.4	-0.4	1.2	-1.1	-1.0	-0.1	-0.2	-1.1	-0.6
Medication: Aspirin	0.8	1.1	3.6	-0.6	0.2	-1.9	0.5	-1.6	-0.9	-0.6	0.1	-0.9	-0.5	1.8	-0.9	-1.6	-0.1	-0.2	-0.8	-1.5
Mood swings	0.8	1.5	4.8	0.5	1.4	0.7	0.1	1.4	1.8	0.6	1.0	1.8	-0.0	0.5	1.7	0.9	1.2	2.2	1.0	1.3
Ever had bowel cancer screening	0.8	0.9	3.6	-1.9	-0.2	1.0	0.7	0.6	-0.7	-1.7	0.3	-0.7	-0.5	0.2	-1.0	0.6	0.5	1.3	-1.6	-0.2
Diabetes diagnosed by doctor	0.8	1.3	4.6	2.1	0.8	0.7	-1.5	-2.1	0.6	1.9	0.0	0.6	0.1	-0.6	0.9	-0.2	-0.1	-0.3	1.8	-0.1
Commuting to job workplace: Walk	0.8	0.8	2.5	-0.4	1.0	1.2	-0.3	0.6	-0.4	0.4	0.7	-0.1	0.2	0.7	-1.1	-1.5	1.5	0.5	-1.6	-1.2
Breast cancer (self-reported)	0.8	1.0	2.4	1.5	1.1	-0.2	-0.0	0.2	1.2	1.2	1.1	1.4	1.4	-0.1	1.2	0.6	0.2	-0.1	1.4	0.8
Osteoporosis (self-reported)	0.8	1.0	4.9	1.4	0.9	1.7	-0.6	2.2	0.5	0.5	1.2	1.1	0.7	-1.4	0.4	-0.4	0.5	-0.4	0.4	0.2
Hearing aid user	0.8	0.9	4.7	0.1	-0.2	1.4	2.2	1.8	0.6	-0.3	0.5	-0.1	0.3	-0.7	0.2	0.5	1.7	0.9	-0.2	0.8
Eye problems/disorders: Glaucoma	0.8	1.0	3.4	1.5	0.4	1.3	-1.8	-0.1	0.8	1.8	0.3	0.8	0.4	-1.8	0.7	0.3	0.3	-0.4	0.7	0.3
Alcohol drinker status: Never	0.8	1.0	4.6	-0.9	-1.0	-0.3	0.2	-0.5	-0.8	-0.8	0.1	-2.2	0.2	1.5	-1.5	-1.0	1.0	-0.5	-1.1	-0.6
Number of operations (self-reported)	0.8	1.3	5.5	0.7	1.2	-1.3	1.1	1.1	1.2	0.9	2.4	0.4	0.5	-0.9	0.9	1.2	1.3	0.1	0.5	1.4
Ever depressed for a whole week	0.8	1.0	4.0	-1.4	-1.5	-1.4	-0.1	-0.2	-0.8	-2.0	-0.7	-0.7	-0.1	0.7	-0.9	-0.8	0.0	-0.6	-1.6	-0.1
Alcohol drinker status: Previous	0.8	0.9	4.7	1.1	-0.1	1.0	-2.2	0.5	0.6	0.3	-1.4	0.3	-0.7	0.2	0.4	0.1	1.1	1.7	0.7	0.2
Ulcerative Colitis (UC)	0.7	1.3	6.8	-2.1	-1.1	-0.3	1.2	-0.3	-0.5	-2.6	-0.4	-1.2	-0.3	1.5	-0.6	0.5	-0.3	1.1	-1.4	-0.3
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	3.4	0.6	-0.0	-0.1	0.3	0.0	1.3	0.8	0.3	0.9	-1.1	-0.5	1.1	1.5	0.7	1.8	0.5	0.9
Vitamin and mineral supplements	0.7	0.9	2.9	0.6	1.1	1.7	0.2	0.3	0.6	1.1	1.0	1.2	1.2	-0.8	1.0	0.7	0.0	-0.5	1.6	0.5
Pack years adult smoking proportion	0.7	1.1	3.5	-0.2	-1.4	-1.1	-0.1	-0.3	-1.1	-0.8	-1.1	-1.8	-0.8	-0.1	-1.1	-1.9	-0.5	-0.2	-1.1	-1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	2.9	-0.8	-1.7	-0.3	-0.4	0.4	-0.3	-1.2	-0.6	-0.9	-1.1	1.2	-0.9	-0.2	1.2	1.3	-1.4	0.1
Worrier / anxious feelings	0.7	1.3	3.7	1.6	1.8	1.8	-1.9	0.3	1.1	1.0	1.2	0.7	-0.5	-0.2	1.0	0.1	1.1	0.0	0.8	1.0
Mouth/teeth dental problems: Dentures	0.7	1.2	10.1	0.2	1.6	3.2	0.2	1.5	0.7	-0.4	1.1	0.2	0.7	-1.4	0.4	0.6	0.7	0.4	0.1	0.3
Pulse wave reflection index	0.7	0.8	2.3	-0.0	-1.3	0.5	1.3	-0.2	-0.9	-0.6	-0.3	-1.0	-1.5	0.3	-0.9	-1.1	-0.6	-0.5	-1.5	-1.0
Medication for pain relief, constipation, heartburn	0.7	1.1	4.5	1.3	0.2	1.5	-1.2	1.2	0.1	1.0	-0.3	0.5	0.5	-2.1	0.5	-0.2	-1.3	-1.9	0.7	0.4
Family relationship satisfaction	0.7	0.8	3.8	-0.7	-1.0	-1.0	1.4	0.1	0.4	-0.2	-1.4	0.4	1.1	1.0	0.5	1.1	-0.3	1.9	-0.5	0.4
Medication: Aspirin	0.7	1.0	3.5	-0.6	0.3	-1.5	0.4	-1.6	-0.8	-0.5	0.1	-0.9	-0.6	1.9	-0.8	-1.5	-0.2	-0.1	-0.8	-1.3
Mother’s age at death	0.7	0.9	2.6	1.6	0.8	0.6	-1.0	0.4	1.2	0.6	0.4	0.4	1.6	-0.5	0.8	0.5	1.4	-0.6	0.2	1.4
Mean Putamen Volume	0.6	0.6	2.1	0.7	1.0	0.6	0.8	-1.3	0.2	0.1	-1.1	0.2	0.7	-0.4	0.7	0.6	-1.3	-0.5	1.5	0.1
Fasting Glucose	0.6	0.7	2.4	1.4	0.6	1.2	-0.7	0.0	0.6	1.5	-0.1	0.3	-0.2	-0.4	1.1	-0.2	-0.9	-0.4	1.5	0.3
Triglycerides	0.6	1.0	2.5	0.2	1.3	0.6	0.3	0.5	1.4	1.0	0.7	1.3	0.9	0.5	1.3	1.3	0.9	1.1	0.6	1.6
Hypothyroidism (self reported)	0.6	1.3	11.8	0.8	1.1	1.0	-3.4	-1.2	0.4	1.0	-0.6	0.6	-0.3	1.2	-0.1	-0.1	1.7	-0.3	0.1	0.3
Ever used hormone-replacement therapy (HRT)	0.6	0.7	2.7	0.5	1.2	-1.4	0.3	1.2	0.6	0.5	1.6	0.4	0.8	0.1	0.2	0.8	1.4	0.2	0.1	0.9
Hand grip strength (right)	0.6	1.7	4.9	-1.2	-1.6	-1.4	0.8	-2.2	-1.7	0.2	-1.5	-0.9	-1.4	0.7	-1.4	-0.8	-1.4	-1.0	-1.2	-1.2
Fed-up feelings	0.6	1.1	5.1	1.3	0.6	1.9	-1.3	0.6	1.1	0.3	-0.4	-0.3	-0.7	-0.3	0.5	0.5	2.3	0.9	0.5	1.2
Allergy	0.6	1.5	3.7	-1.0	-0.5	-0.1	-1.9	-0.6	-1.3	-1.0	-1.3	-1.5	-1.9	1.8	-1.3	-1.0	-0.3	0.3	-1.3	-1.4
Qualifications: A levels/AS levels or equivalent	0.6	1.4	8.8	1.2	-0.0	-0.6	3.0	2.2	0.5	1.6	0.1	1.5	1.0	-0.4	0.8	-0.2	-0.6	-0.5	1.1	0.2
Asthma	0.6	1.2	4.6	1.3	-0.0	-1.0	2.2	1.0	1.1	0.5	0.5	0.6	1.2	-1.3	1.3	1.1	0.4	0.3	1.2	1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	2.9	0.5	-0.0	-0.5	1.5	1.7	0.5	-0.1	0.7	0.1	-0.6	1.0	-0.1	0.6	1.7	0.7	-0.3	0.9
Emphysema/chronic bronchitis	0.6	0.6	2.3	-0.8	-1.2	-0.2	-0.0	0.0	-0.4	-1.5	-0.6	-0.7	-1.3	0.6	-0.8	-0.1	0.3	1.1	-1.0	-0.7
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.7	0.8	-0.1	-0.4	0.6	-0.9	0.2	0.4	0.0	0.3	0.5	-1.1	0.7	0.6	-1.6	-1.3	1.6	0.4
Mineral and other dietary supplements	0.6	0.7	5.2	-0.7	-0.2	2.3	0.2	-1.2	0.1	-0.2	-0.1	0.5	0.9	-1.5	0.6	0.7	-0.9	-0.1	0.4	0.4
Illnesses of father: None of the above (group 1)	0.6	0.8	2.7	-0.0	0.2	1.6	1.5	1.6	0.6	-0.3	0.5	0.4	0.2	-0.9	0.3	1.0	0.9	0.8	1.0	0.6
High cholesterol (Self-reported)	0.6	1.1	4.9	0.7	1.3	1.1	2.2	0.4	0.6	0.7	2.2	0.3	0.1	0.0	0.2	0.4	1.6	0.4	0.7	0.4
Fractured/broken bones in last 5 years	0.6	0.8	2.8	-0.7	-0.7	-1.2	-0.6	-0.6	-0.6	0.4	-0.9	-0.6	-0.4	1.7	-0.9	0.2	0.9	1.5	-1.1	-0.5
Depression (Nagel 2018)	0.5	0.8	3.1	-0.3	-1.5	-1.4	-0.1	0.2	-0.1	-0.5	-0.4	-0.9	-0.8	0.6	-0.8	-0.5	1.8	1.1	-1.4	0.1
Breast Cancer	0.5	1.2	3.1	-1.6	-0.6	-0.9	1.6	-0.7	-1.2	-0.9	-1.4	-0.8	-0.8	-0.2	-1.0	-0.7	-1.8	-0.5	0.1	-1.7
Type 2 Diabetes (T2D) (2012)	0.5	0.5	3.8	-0.3	0.5	-0.5	-0.9	-1.9	-0.4	1.2	-1.0	-0.1	-0.6	0.1	-0.3	0.5	-0.7	-0.2	0.2	-0.4
Blood Eosinophil Count	0.5	4.0	39.4	0.3	0.4	-1.2	-6.3	-2.5	-0.6	0.5	-2.3	-0.9	-0.8	3.2	-1.0	-1.2	0.4	-0.9	-0.4	-1.0
Frequency of depressed mood in last 2 weeks	0.5	0.6	2.0	-0.2	-1.4	-1.2	0.6	0.1	0.4	0.0	-0.4	0.1	-0.6	0.7	0.1	0.4	1.4	1.4	-0.8	0.9
Hearing difficulty/problems: Yes	0.5	0.7	4.0	-0.5	-0.7	0.8	2.0	1.9	0.2	-0.7	0.7	0.2	-0.7	0.4	0.2	1.0	0.4	0.6	0.1	0.8
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	2.6	-1.5	-0.1	0.4	-0.2	-0.1	-0.7	-0.5	-0.4	-0.3	-1.6	1.3	-0.7	0.1	-0.3	1.4	-0.8	-0.9
Hayfever, allergic rhinitis or eczema	0.5	1.0	5.2	0.5	0.0	-0.3	1.2	-0.2	1.1	0.9	0.8	1.4	2.3	-1.0	1.1	0.8	0.3	-0.1	1.0	1.3
High blood pressure (mother)	0.5	0.8	2.3	0.8	0.9	0.2	-1.5	-0.5	0.6	1.5	0.3	1.1	0.3	-0.4	1.0	0.5	-1.0	-0.6	1.5	0.3
Nervous feelings	0.5	0.9	2.8	-0.7	-0.4	-1.1	-1.5	-0.8	-0.4	-0.6	-0.5	-1.2	-1.3	1.5	-0.6	-0.5	0.4	1.0	-1.7	-0.1
Qualifications: None of the above	0.5	1.0	4.1	-0.5	1.2	0.9	-0.1	0.8	0.1	-1.5	1.6	-1.2	-1.5	0.1	-0.6	0.5	2.0	0.8	-0.6	0.3
Medication: Ramipril	0.5	0.7	2.9	0.9	0.9	-1.0	1.1	-0.1	0.6	1.0	1.7	0.7	0.2	0.5	0.3	0.3	1.1	0.3	0.8	0.4
Illnesses of siblings	0.5	0.7	2.9	-0.3	0.7	1.0	0.7	0.7	0.6	0.2	0.2	1.2	0.4	-1.7	1.0	1.0	-0.3	1.3	0.0	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	2.4	-1.4	-0.1	-0.8	0.5	-0.5	-0.6	-1.0	-0.4	-0.4	-0.4	1.6	-0.8	-0.4	0.5	0.8	-0.9	-0.6
Depression (self-reported)	0.5	0.6	1.5	0.8	-0.9	-0.1	-0.8	1.0	0.6	-1.0	-1.2	0.1	-1.2	-0.5	0.6	0.2	0.3	0.6	0.6	0.8
Pulse wave Arterial Stiffness index	0.5	0.6	3.8	1.4	-0.3	0.3	2.0	0.9	0.2	0.9	0.2	0.1	-0.6	0.4	0.1	0.1	0.7	-0.7	0.2	0.4
Loud music exposure frequency	0.5	0.5	1.5	-0.9	-0.5	-1.2	0.2	0.2	-0.4	-0.5	0.8	-0.5	-0.5	0.8	-0.5	-0.3	0.4	1.2	-1.2	-0.6
High blood pressure (siblings)	0.5	0.7	2.2	-0.9	-0.2	-0.4	-0.1	-1.5	-1.1	-0.8	0.4	-1.1	-0.9	1.1	-1.0	-0.4	-0.7	-1.3	-0.2	-0.7
Wheeze or whistling in the chest in last year	0.5	0.9	4.5	0.2	0.6	-0.3	1.6	1.0	0.8	-0.7	0.8	0.6	-0.0	-0.5	0.9	0.9	0.9	2.1	0.2	1.1
Shortness of breath walking on level ground	0.5	0.5	1.9	1.4	-0.5	-0.7	0.5	-0.6	0.2	1.2	-0.2	0.0	-0.6	-0.9	0.5	-0.5	-0.8	-1.0	1.0	0.2
Medication: Blood pressure	0.5	0.9	2.8	-0.8	-0.4	-1.4	-0.8	-1.2	-0.9	-0.8	0.5	-0.8	-1.7	1.1	-0.9	-0.9	-0.3	-0.2	-0.4	-1.3
Number of full sisters	0.5	0.6	2.5	0.1	0.7	0.4	1.6	1.4	0.0	-0.3	1.6	-0.2	-1.0	-0.6	-0.0	0.1	-0.3	-0.6	0.3	0.3
Suffer from ‘nerves’	0.5	0.8	3.7	-0.2	-1.3	-1.3	-1.5	0.2	-0.2	-0.4	-0.9	-0.7	-1.9	1.3	-0.2	-0.2	0.3	-0.2	-0.0	0.6
Leg pain on walking	0.5	0.6	2.2	1.0	-0.2	-1.0	1.0	1.2	0.4	0.8	0.4	0.3	-0.0	-0.3	0.3	0.6	0.5	-1.5	0.4	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.5	1.9	0.5	0.3	0.3	1.4	0.1	0.9	0.3	0.9	0.8	0.0	-1.0	0.7	0.9	0.7	0.3	0.9	0.9
Asthma (self-reported)	0.5	1.0	5.7	1.2	-0.5	-1.3	2.4	0.8	0.8	0.4	0.1	0.3	1.1	-1.1	1.0	0.7	0.3	0.2	1.0	1.4
Medication: Gliclazide	0.5	0.6	1.9	0.6	0.8	0.2	-1.2	-1.3	0.7	1.0	0.6	0.4	1.4	-0.6	0.6	0.3	1.0	0.4	0.7	0.3
Average weekly champagne plus white wine intake	0.5	0.7	3.8	-0.6	-0.4	-0.9	-0.5	0.0	-0.5	-0.5	-0.6	-0.6	0.4	1.5	-0.9	-0.7	1.3	0.7	-2.0	-0.3
Miserableness	0.5	0.8	4.2	-0.9	0.2	0.9	-0.4	-0.2	0.1	-0.8	0.4	-0.1	-1.9	1.4	-0.1	0.6	0.8	2.0	0.0	0.3
Medication: Blood pressure	0.5	1.0	4.5	0.6	1.4	-0.1	1.2	-0.8	0.5	2.1	1.9	0.4	1.4	0.5	0.3	0.5	0.9	-0.5	0.3	0.7
Average weekly beer plus cider intake	0.5	0.7	4.3	0.6	0.2	0.1	0.6	-0.1	0.4	0.0	0.9	-0.1	-0.9	-2.1	0.8	0.2	-0.6	-1.7	0.8	0.9
Pack years of smoking	0.5	0.7	3.1	0.1	-0.9	-1.2	-0.0	-0.2	-0.8	-0.5	-1.0	-1.3	-0.5	-0.3	-0.7	-1.8	-0.6	-0.1	-0.7	-1.3
Schizophrenia (2018)	0.4	0.7	2.0	-0.6	-0.9	0.0	-1.1	0.0	-1.3	-0.6	-0.2	-1.4	-1.1	-0.6	-1.2	-0.8	-0.6	-0.9	-0.9	-0.9
Schizophrenia vs Biploar Disorder	0.4	0.6	3.0	-1.1	0.9	1.7	-0.3	0.3	-0.5	-1.1	0.3	-0.9	-0.7	0.2	-0.5	1.0	0.5	0.2	0.2	0.3
Worry (Nagel 2018)	0.4	0.8	4.6	0.2	-0.2	-0.3	-2.1	-0.7	-0.1	-0.3	0.0	-1.1	-1.8	1.5	-0.4	-0.2	1.1	-0.0	-0.3	0.4
Alzheimer’s Disease (including proxy)	0.4	0.6	2.9	-0.4	-1.1	0.4	-1.7	0.1	-0.2	-1.0	-1.1	-0.7	-1.1	0.9	-0.5	-0.2	0.9	0.4	0.1	-0.3
Reaction Time	0.4	0.7	5.1	-0.0	-0.6	0.4	-2.3	0.6	-0.3	-0.4	-0.6	-0.6	-1.7	-1.1	-0.2	0.2	-0.4	0.1	0.3	0.2
Ovarian Cancer	0.4	0.6	3.5	0.2	-0.8	-1.9	-1.7	-0.3	-0.2	0.5	0.2	0.1	-0.4	1.0	0.1	-0.6	-0.6	-0.5	-0.4	0.1
Prostate Cancer	0.4	0.6	1.8	-0.8	0.5	-0.4	-0.9	-1.1	-0.7	0.2	0.8	-0.5	0.2	0.4	-0.8	-1.3	-0.0	-1.0	-1.1	-0.7
Blood White Count	0.4	2.6	9.2	0.4	1.6	-0.1	1.6	2.8	1.8	-0.3	0.7	1.7	1.5	-0.1	1.4	2.1	2.1	3.0	1.1	1.4
Cardiovascular Disease	0.4	1.3	3.2	1.2	1.0	-0.2	1.0	0.2	1.4	1.8	1.6	1.4	0.9	-0.4	1.3	0.8	1.0	1.1	1.3	1.2
Respiratory disease	0.4	0.8	4.9	0.8	-1.1	-1.1	2.2	1.7	0.3	-0.6	-0.2	-0.5	-0.4	-0.6	0.3	0.8	0.3	0.6	0.4	0.9
Number of treatments/medications taken	0.4	0.7	2.2	-0.5	0.1	-0.7	-0.6	-1.5	-0.7	-0.6	0.3	-1.3	-0.7	1.1	-1.1	-0.9	1.0	-0.2	-0.5	-0.9
Ever had hysterectomy (womb removed)	0.4	0.5	2.3	0.3	0.3	-0.4	0.9	0.5	0.8	0.1	0.8	0.3	0.3	0.9	0.4	0.6	1.2	1.5	0.5	0.4
Supplements: Zinc	0.4	0.4	2.4	-0.3	0.1	-0.4	0.1	0.6	-0.0	-0.5	-0.0	0.1	-1.4	0.8	0.0	-0.1	-0.4	1.6	-0.3	-0.6
Severe depression (siblings)	0.4	0.4	1.5	0.7	0.2	-0.4	0.8	1.1	0.4	1.2	0.3	0.8	-0.3	-0.3	0.6	0.2	-0.5	-0.3	0.8	0.3
Townsend deprivation index at recruitment	0.4	0.6	2.8	-0.2	0.6	1.7	1.1	1.0	-0.1	-1.1	1.5	-0.4	-0.2	-0.5	-0.3	-0.1	0.4	0.1	-0.6	-0.2
Current tobacco smoking	0.4	0.6	3.0	0.1	-0.2	-0.0	-0.5	-1.1	-0.1	-0.1	-1.7	-0.1	-0.1	-0.8	0.5	-0.3	-1.7	0.9	0.5	-0.9
Maternal smoking around birth	0.4	0.6	3.6	-1.2	0.3	0.2	0.9	0.3	-1.0	-0.3	1.9	0.0	-0.6	-0.5	-0.7	-0.1	-0.6	-0.0	-1.3	-0.5
Age when periods started (menarche)	0.4	1.1	3.8	-0.6	-0.1	-0.5	-0.5	0.1	-1.0	-0.7	-0.7	-0.8	-2.0	1.6	-1.1	-1.8	-0.4	-0.3	-1.2	-1.3
Multivitamins +/- minerals	0.4	0.5	2.4	0.2	-1.3	-1.5	-0.2	0.3	0.2	0.1	-0.8	-0.4	-0.8	-0.0	-0.0	-0.1	-0.1	0.9	-1.0	0.4
Chronic bronchitis/emphysema (father)	0.4	0.4	1.7	-1.3	0.9	-0.3	-0.3	-0.5	-0.1	-1.2	0.9	-0.1	0.5	-0.0	-0.1	0.6	0.1	0.3	-0.9	0.2
Hair/balding pattern: Pattern 3	0.4	0.6	2.8	0.5	-0.0	-1.7	-1.1	-0.8	-0.4	0.4	0.4	-0.5	0.1	0.4	-0.7	-1.4	0.2	-1.2	-0.0	-0.9
Noisy workplace	0.4	0.5	3.5	-0.9	0.6	-0.4	-0.0	-0.2	0.3	-0.9	0.0	0.3	-1.0	0.5	0.4	0.9	0.7	1.9	-0.3	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	1.8	0.1	0.3	-1.0	0.6	1.4	0.2	0.1	0.4	0.2	0.2	0.9	-0.2	-1.2	1.0	0.1	-1.0	0.1
Length of working week for main job	0.4	0.5	1.6	0.8	-0.3	0.3	-1.1	-0.3	-0.5	-0.4	-0.1	-0.9	-0.2	0.6	-0.9	-0.8	0.8	-1.3	0.1	-0.3
Hair/balding pattern: Pattern 4	0.4	1.0	3.3	0.2	0.6	-0.9	-0.5	0.3	1.3	0.7	-0.1	1.1	0.4	0.0	1.1	1.8	1.4	1.4	-0.1	1.8
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	3.4	0.7	1.6	0.6	-1.2	-0.2	0.6	0.8	0.1	0.7	-0.0	1.7	0.1	-0.0	1.9	0.4	0.2	0.3
Exposure to tobacco smoke outside home	0.4	0.5	2.0	0.3	-0.3	-1.3	1.1	0.5	-0.4	0.1	1.4	-0.5	-1.4	0.1	-0.3	-0.1	-0.5	-0.6	-0.7	0.4
Heart disease (mother)	0.4	0.5	2.1	-0.4	-0.4	-1.3	0.1	-1.3	-0.6	-0.7	-0.9	-0.9	0.1	0.3	-0.2	-0.1	-1.4	-0.2	0.0	-0.7
Age at last live birth	0.4	0.6	1.7	0.7	1.3	-0.3	-1.0	-0.1	0.8	1.0	-0.5	1.2	0.9	0.7	1.0	0.3	-0.0	0.6	0.8	0.5
Illnesses of siblings: Diabetes	0.4	0.5	2.6	0.4	-0.3	-1.5	-0.8	-0.8	0.5	0.8	-0.0	0.0	0.3	1.6	0.1	0.1	0.8	-0.0	0.4	0.4
Average weekly red wine intake	0.4	0.5	2.4	-0.6	-0.3	0.5	0.3	0.5	-0.9	-0.2	0.2	-0.5	-1.2	0.0	-0.9	-1.5	-0.4	-0.6	-1.2	-0.6
Loneliness, isolation	0.4	0.5	3.0	-0.4	-0.7	0.0	0.5	0.2	-0.1	-0.8	-0.7	-0.2	-1.6	0.4	-0.2	0.2	0.4	1.7	-0.5	0.0
Eye problems/disorders: Cataract	0.4	0.4	1.8	0.4	0.7	-0.2	-1.3	0.1	0.7	0.4	0.0	0.6	-0.1	0.1	0.4	0.5	1.1	1.3	0.6	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.8	-0.7	-1.2	-0.5	1.4	1.0	-0.2	-0.8	0.4	-0.4	-0.5	0.6	-0.4	-0.3	0.6	1.1	-1.4	0.1
Guilty feelings	0.4	0.7	3.2	1.3	0.4	0.4	1.0	0.9	0.4	1.5	1.8	0.7	-0.7	-0.5	0.3	-0.4	0.7	0.3	0.3	0.2
Unable to work because of sickness or disability	0.4	0.5	2.1	0.8	-0.4	-1.3	-1.4	1.2	-0.0	-0.4	-0.7	-0.2	-1.0	-0.1	-0.4	-0.7	0.5	0.3	-0.7	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.2	0.3	0.1	0.3	-1.0	-0.6	0.3	0.9	-0.0	0.7	1.3	-1.5	0.6	0.0	-0.8	-0.8	-0.3	0.3
Heart disease (siblings)	0.4	0.5	2.3	-0.8	-1.5	-0.5	-0.3	0.1	-0.8	-0.9	-0.8	-0.9	-0.6	0.6	-0.8	-0.5	-0.3	0.3	-0.2	-1.1
Depressed Affect (Nagel 2018)	0.3	0.5	2.0	-0.1	0.0	0.4	-1.4	0.3	0.1	-0.5	-0.2	-0.7	-1.4	0.9	-0.4	-0.3	1.3	1.1	-0.4	0.0
Intelligence (Savage-Jansen 2018)	0.3	1.0	6.6	0.6	0.6	-0.1	1.5	1.1	0.8	1.1	1.2	1.3	2.6	-0.3	0.8	0.0	0.1	-0.4	0.4	0.5
Neuroticism (Nagel 2018)	0.3	0.8	4.9	-0.2	-0.4	-0.4	-1.1	-0.6	-0.4	-0.9	-0.3	-1.2	-2.2	1.4	-0.7	-0.7	0.8	0.3	-0.4	-0.3
Body Mass Index (BMI) (2010)	0.3	0.5	1.6	-1.3	-0.1	-0.2	0.9	-0.8	-1.0	-0.6	-0.6	-0.4	-0.3	0.1	-0.9	-0.7	-0.3	-0.3	-0.8	-0.9
HbA1C	0.3	0.4	1.2	1.0	1.1	0.1	-1.1	-0.2	0.1	0.6	0.7	0.0	-0.2	0.4	0.1	-0.7	-0.5	-0.5	1.0	-0.4
Rheumatoid Arthritis	0.3	0.5	2.1	1.3	0.3	0.7	-0.0	0.5	0.8	0.7	0.7	0.2	-0.4	-0.4	0.7	0.2	0.5	-0.9	1.5	0.2
BMI	0.3	1.6	10.1	0.4	1.3	1.4	0.5	0.9	0.6	1.4	1.2	0.9	3.2	-1.2	0.4	1.3	1.8	-0.2	-0.1	1.2
Waist Hip Ratio (WHR)	0.3	1.4	4.1	0.4	0.8	0.1	-0.5	0.6	0.9	0.3	-1.4	1.3	-0.0	0.5	1.6	2.0	-2.0	1.4	2.0	0.4
Neuroticism	0.3	0.8	3.6	0.4	0.3	1.4	-1.1	0.1	0.1	-0.3	1.0	-0.8	-1.9	0.7	-0.5	-0.4	1.6	0.2	-0.7	0.2
Sensitivity / hurt feelings	0.3	0.5	2.3	-1.1	0.1	0.3	-0.7	-1.3	-0.5	-0.5	0.1	-0.6	-0.8	0.7	-0.4	-0.6	-0.1	-0.1	-1.5	-0.1
Angina	0.3	0.3	2.0	0.2	0.7	1.4	-0.3	-0.1	-0.1	0.0	0.6	-0.3	-1.0	-0.5	-0.1	-0.4	0.7	0.7	-0.5	-0.1
Medication: Co-codamol	0.3	0.3	1.1	0.5	-0.4	-0.8	-0.6	0.8	0.3	-0.4	-0.7	-0.5	-0.1	-0.1	-0.0	0.5	0.8	1.0	0.2	0.1
Supplements: Glucosamine	0.3	0.4	3.1	0.3	0.1	-1.6	0.3	-0.2	-0.2	0.3	0.2	0.1	0.0	-0.4	-0.1	-0.5	-0.8	-1.8	0.2	-0.3
Medication: Atenolol	0.3	0.3	1.5	1.1	0.2	0.4	-0.4	-0.1	0.3	1.2	0.3	0.4	0.3	-0.7	0.3	-0.1	0.2	-0.3	1.1	-0.1
Body mass index (BMI)	0.3	1.5	7.2	0.8	1.7	1.5	0.6	0.6	0.4	1.3	1.6	0.8	2.7	-1.3	0.4	0.6	1.6	-0.8	0.0	1.0
Hearing difficulty/problems with background noise	0.3	0.5	2.9	0.1	-0.2	0.4	1.1	1.7	0.3	-0.4	0.4	0.3	-0.3	-0.2	0.1	1.1	1.0	0.4	0.7	0.7
Had menopause	0.3	0.4	2.8	0.1	1.1	0.9	-0.5	-0.3	0.2	0.1	1.2	-0.2	1.7	-0.0	-0.1	0.4	0.4	-0.6	0.1	-0.1
Heart attack	0.3	0.4	1.7	-0.2	0.1	0.5	1.2	-0.0	-0.6	0.1	0.5	-0.6	-1.3	0.1	-0.7	-0.4	0.4	0.4	-0.6	-0.8
Pain all over the body in last month	0.3	0.3	1.1	0.7	0.2	0.2	0.2	1.1	0.5	-0.1	0.7	0.5	0.5	-0.5	0.2	-0.2	0.9	0.6	0.1	0.1
Neuroticism score	0.3	0.6	2.8	0.1	0.5	0.9	-0.5	0.4	0.6	-0.1	1.0	-0.0	-1.4	0.5	0.3	0.5	1.7	1.1	-0.3	1.1
Father’s age at death	0.3	0.4	1.5	0.9	-0.1	0.3	0.6	1.2	-0.1	0.4	0.1	-0.3	0.6	-0.3	-0.4	-1.1	0.6	-0.5	-1.2	-0.1
Number of live births	0.3	0.5	1.9	-1.3	-0.6	0.2	0.4	0.8	-0.6	-0.6	0.0	-0.7	-1.4	0.2	-1.1	0.0	0.8	-0.5	-0.1	-0.6
Medication: Cholesterol lowering	0.3	0.5	2.4	0.8	0.6	-0.6	1.2	-0.3	0.3	0.6	1.6	0.2	-0.9	0.4	0.4	-0.2	-0.0	-0.4	0.8	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	2.1	0.1	-0.6	-0.2	0.5	1.5	0.5	-0.1	0.3	0.5	0.2	0.2	0.3	0.7	1.0	0.7	-0.2	0.9
Peak expiratory flow (PEF)	0.3	0.8	2.8	-1.3	-1.7	-1.2	1.3	0.0	-0.7	-0.9	-0.4	-1.0	-0.5	-0.2	-1.1	0.5	0.8	-0.6	-0.0	-0.3
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.8	0.3	-1.2	-0.9	-0.1	-0.5	-0.1	1.2	-1.4	0.4	-0.6	-0.2	0.2	-0.0	-0.8	-0.7	0.8	-0.1
Blood clot in the leg (DVT)	0.3	0.4	2.2	0.1	0.2	0.3	-0.9	-0.3	0.3	0.6	0.2	0.7	1.3	-1.5	0.5	-0.0	-0.7	-0.7	-0.4	0.2
Glaucoma (self-reported)	0.3	0.3	1.2	0.5	-0.0	1.1	-1.0	-0.2	0.4	1.1	0.2	0.5	0.0	-0.7	0.5	0.3	0.1	0.2	0.3	-0.0
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.1	0.8	1.0	-1.0	0.3	0.1	0.2	0.9	0.5	0.3	-0.5	0.0	0.3	-0.8	-0.3	-0.8	0.6	-0.4
Worry too long after embarrassment	0.3	0.4	1.8	-0.2	0.1	1.3	0.3	0.7	-0.1	-0.7	0.5	-0.7	-1.1	0.9	-0.5	-0.1	1.0	0.2	-0.4	-0.1
Number of children fathered	0.3	0.4	1.9	-0.9	-0.1	-0.0	0.1	-0.2	-0.3	-0.5	0.8	-0.3	0.5	-0.9	-0.2	-0.5	-0.7	-1.4	-0.8	-0.5
Age at first live birth	0.3	0.5	2.1	0.9	0.3	-1.4	0.2	-0.1	0.3	1.1	-0.4	0.9	1.0	0.9	0.6	-0.6	-0.6	-0.3	0.4	0.2
Qualifications: College or University degree	0.3	0.8	3.3	0.5	-0.3	-1.8	1.4	1.4	0.3	0.6	0.3	0.9	1.6	1.3	0.2	0.4	0.1	-0.1	0.4	0.3
Mean time to correctly identify matches	0.3	0.5	4.7	0.1	-0.0	0.7	-2.2	0.2	-0.2	-0.6	0.2	-0.6	-1.1	-0.9	-0.3	0.0	0.3	-0.5	0.1	0.4
Alcohol intake frequency.	0.3	0.8	4.1	0.4	-0.2	1.7	-0.6	1.4	0.7	0.0	-0.1	0.0	0.8	-0.4	-0.1	-0.0	2.0	1.5	-0.1	0.2
Knee pain experienced in last month	0.3	0.5	2.8	-0.3	0.0	1.7	-1.1	0.7	0.1	-0.2	0.8	-0.6	-0.5	-0.4	-0.3	0.1	0.5	-0.7	-0.7	0.5
Illnesses of father: Heart disease	0.3	0.4	2.5	-0.0	-1.0	-1.6	0.5	0.1	-0.4	-0.5	-0.2	-0.7	-0.5	0.7	-0.4	-0.5	-0.6	-0.3	0.3	-0.7
Smoking status: Current	0.3	0.6	2.8	0.2	-0.1	0.1	-0.8	-1.0	-0.1	0.0	-1.7	0.0	-0.3	-0.6	0.5	-0.3	-1.7	0.7	0.6	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	2.5	0.7	-0.9	1.2	1.3	0.0	0.2	0.6	0.1	0.1	-0.2	-1.6	0.3	0.8	-0.1	-1.4	0.8	0.8
Supplements: Fish oil (including cod liver oil)	0.3	0.4	2.3	0.2	0.7	-1.2	-1.0	0.7	0.2	-0.0	-0.2	-0.2	0.2	1.5	-0.2	0.0	0.7	0.9	-0.6	0.0
Risk taking	0.3	0.5	4.4	-0.8	-0.5	-0.8	2.1	-0.4	-0.4	-0.8	-0.3	-0.1	0.4	-0.6	-0.4	0.1	-0.1	-0.2	-0.2	-0.0
Myopia	0.3	0.4	2.7	0.8	-0.6	-0.1	0.3	0.4	-0.2	-0.0	-0.2	-0.2	-0.3	-1.3	-0.0	-1.1	-0.1	-1.7	0.5	0.1
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.9	-0.0	0.1	0.7	1.4	0.4	-0.4	0.0	0.6	-0.6	-1.2	-0.1	-0.7	-0.4	0.8	0.2	-0.4	-0.6
Coronary Artery Disease (CAD)	0.2	0.2	1.4	-0.4	0.6	0.1	0.0	0.2	0.1	0.3	0.5	0.2	0.7	1.2	0.0	0.2	0.2	1.0	-0.4	-0.3
Neuroticism (2016)	0.2	0.3	0.7	0.2	-0.2	-0.7	-0.8	0.5	-0.0	0.0	0.1	0.7	-0.8	0.8	0.5	0.5	-0.6	0.7	0.4	0.5
Ulcerative Colitis	0.2	0.3	1.1	-0.9	-0.4	-0.6	0.5	0.3	0.1	-1.0	0.4	-0.5	0.2	0.9	0.1	0.2	-0.1	0.1	-0.6	0.3
Blood Red Count	0.2	1.9	21.0	0.7	0.9	1.6	0.6	0.5	0.4	1.4	1.2	0.5	4.6	-0.3	0.3	-0.1	1.0	-0.9	-0.1	0.7
High blood pressure	0.2	0.6	2.4	0.9	1.0	0.2	-0.1	-1.2	0.5	1.6	1.4	0.5	0.6	0.3	0.4	0.4	1.0	-0.2	0.8	0.5
Trunk fat mass	0.2	0.7	3.2	-0.4	0.7	-0.0	0.4	-1.8	-1.0	0.1	-0.3	-0.4	1.8	-0.3	-0.9	-0.4	0.3	-1.4	-0.5	-0.7
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	2.0	-0.4	0.4	-0.5	0.9	-0.3	-0.2	0.0	0.4	0.6	0.4	-0.1	0.2	-0.4	-1.4	-0.0	0.6	-0.8
Medication: Simvastatin	0.2	0.3	1.9	0.0	-0.2	-0.5	-0.5	-1.4	-0.5	-0.2	-0.3	-0.8	-0.7	0.3	-0.5	-0.2	0.0	-0.5	0.1	-0.5
Hip circumference	0.2	1.0	3.3	-0.5	-0.3	-0.0	1.3	-0.3	-1.0	0.1	-0.0	-0.6	1.8	-0.4	-1.3	-0.8	1.7	-0.8	-1.8	-0.4
Alcohol intake versus 10 years previously	0.2	0.4	1.5	-0.1	-0.7	0.8	1.2	0.7	-0.3	-0.9	0.1	-0.4	-0.1	-0.7	-0.4	-0.3	0.3	0.7	-0.4	-0.6
Prospective memory result	0.2	0.3	1.1	-0.5	0.3	-0.4	0.2	-0.3	-0.7	-0.8	-1.0	-0.4	-0.2	0.0	-0.6	-0.4	-0.5	-0.4	-0.3	-0.5
Exposure to tobacco smoke at home	0.2	0.2	1.0	0.0	-0.7	-1.0	0.4	-0.8	0.0	0.3	0.3	-0.3	-0.2	-0.0	0.2	-0.3	-0.5	-0.0	-0.4	-0.1
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	2.2	-0.4	-0.9	0.6	0.3	0.3	-0.4	-0.3	-1.5	-0.2	0.7	-1.0	-0.4	0.0	-0.6	-0.3	-0.5	0.0
Medication: Ventolin 100micrograms inhaler	0.2	0.2	1.1	0.3	-0.6	-0.4	0.4	-0.2	0.2	-0.1	-0.4	-0.2	0.6	-0.6	0.6	-0.3	-1.1	0.3	0.6	-0.1
Comparative body size at age 10	0.2	0.4	1.9	0.2	0.3	0.3	-0.7	-0.1	0.5	0.9	-0.1	0.6	-0.2	0.4	0.3	0.3	1.3	0.5	-1.4	1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.1	0.9	-0.1	-0.5	0.3	-0.5	-0.1	1.0	0.2	-0.6	-0.7	0.3	-0.2	0.0	0.3	-0.9	0.6	0.3
Angina (self-reported)	0.2	0.3	1.0	0.2	0.5	1.0	-0.4	-0.4	-0.2	0.0	0.5	-0.5	-1.0	-0.1	-0.3	-0.7	0.7	0.6	-0.7	-0.4
Whole body fat mass	0.2	0.7	2.8	-0.6	0.5	0.1	0.5	-1.7	-1.2	-0.1	-0.2	-0.5	1.7	-0.4	-1.0	-0.5	0.1	-1.4	-0.8	-0.8
Leg fat mass (right)	0.2	0.6	3.8	-0.9	0.5	0.4	0.4	-1.3	-1.0	-0.1	-0.3	-0.1	2.0	-0.4	-0.7	-0.2	-0.2	-0.9	-1.0	-0.4
Pulse rate, automated reading	0.2	0.6	2.2	-0.5	-0.4	-0.2	-0.4	-0.3	-0.7	-0.8	-1.1	-0.5	-1.2	1.5	-0.8	-0.6	0.0	0.9	-0.7	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.8	-0.9	-0.7	0.1	0.7	-0.6	-0.5	-0.1	0.2	-0.4	-0.0	-0.3	-0.3	-0.7	-0.6	-0.1	-0.7	-0.4
Hypertension (Self-reported)	0.2	0.5	1.9	0.6	1.0	-0.0	-0.3	-1.3	0.4	1.4	1.3	0.3	0.5	0.4	0.3	0.3	0.9	-0.1	0.5	0.4
Long-standing illness, disability or infirmity	0.2	0.3	1.3	0.5	-0.3	0.1	0.4	0.8	0.6	-0.2	-0.5	0.3	-0.9	-1.1	0.6	-0.1	-0.7	0.2	1.0	-0.3
Ever taken oral contraceptive pill	0.2	0.2	2.0	-0.2	-0.1	-0.7	-0.3	-0.1	-0.2	-0.2	-1.4	0.4	-0.6	0.2	-0.0	0.5	-0.5	-0.2	0.4	0.1
Medication: Bendroflumethiazide	0.2	0.2	1.5	-0.1	1.2	0.0	-0.2	-0.9	-0.2	0.8	0.6	0.1	0.4	0.3	-0.1	-0.2	-0.2	-0.4	-0.1	-0.3
Age started oral contraceptive pill	0.2	0.3	1.5	0.4	1.2	0.6	-0.3	0.2	0.1	-0.0	0.7	0.0	1.1	0.5	-0.2	-0.6	0.4	-0.0	-0.4	-0.4
Leg fat mass (left)	0.2	0.6	4.3	-0.3	0.7	0.4	0.3	-1.2	-0.8	0.3	0.1	0.0	2.1	-0.7	-0.5	-0.2	0.2	-1.2	-0.8	-0.2
Bipolar Disorder or Schizophrenia	0.1	0.2	1.2	0.3	-0.8	-0.3	-0.0	0.9	-0.1	0.0	0.4	-0.6	0.0	-1.1	-0.1	0.4	-0.0	-0.0	0.4	0.1
Age at First Birth	0.1	0.2	1.2	-0.8	-0.1	-0.1	-0.1	-0.3	0.2	-0.3	0.2	0.1	0.1	1.1	0.1	-0.3	0.7	0.8	-0.4	0.1
Schizophrenia (2014)	0.1	0.2	0.9	-0.2	-0.4	-0.1	-0.3	0.4	-0.6	-0.2	-0.4	-0.9	-0.7	-0.5	-0.4	0.1	-0.6	-0.4	0.1	-0.1
Tanning	0.1	1.6	7.0	-2.1	-0.6	-0.2	-1.1	-0.6	-1.4	-2.6	-0.8	-1.2	-1.5	0.9	-1.6	-0.9	-0.1	-0.3	-0.4	-1.5
Hand grip strength (left)	0.1	0.3	0.9	-1.0	-0.4	0.0	-0.3	-0.9	-0.5	0.2	-0.9	0.2	0.4	-0.2	-0.4	0.3	-0.6	0.2	-1.0	-0.1
Taking other prescription medications	0.1	0.2	0.5	0.3	-0.6	-0.2	0.1	-0.5	-0.2	-0.6	-0.7	-0.7	-0.2	-0.0	-0.4	-0.7	0.4	0.3	-0.3	-0.6
Waist circumference	0.1	0.4	3.4	-0.2	0.6	-0.0	0.1	-0.4	-0.6	0.5	-0.1	-0.1	1.9	-0.0	-0.5	-0.1	0.6	-0.6	-0.8	-0.1
Number of incorrect matches in round	0.1	0.2	1.1	-0.1	0.1	0.9	-0.6	0.2	0.4	-0.2	-0.2	-0.4	-0.1	0.4	0.3	0.6	0.7	1.0	0.0	0.3
Pulse rate	0.1	0.2	1.0	0.5	0.4	0.3	-1.0	0.1	0.2	0.2	-0.5	0.2	-0.1	0.3	0.2	-0.5	0.2	-0.3	0.2	0.2
Arm fat mass (right)	0.1	0.6	2.6	-0.3	0.4	0.4	0.2	-1.2	-1.0	0.2	-0.2	-0.4	1.6	-0.6	-0.9	-0.5	0.4	-1.3	-0.7	-0.6
Medication: Seretide 50 evohaler	0.1	0.1	1.2	0.2	0.1	-0.1	-0.1	0.7	0.2	-0.1	0.4	-0.1	-0.1	0.1	-0.0	0.3	1.1	0.4	0.3	0.2
Arm fat mass (left)	0.1	0.5	2.2	-0.2	0.3	0.4	0.3	-1.1	-0.9	0.2	-0.1	-0.4	1.5	-0.5	-0.8	-0.3	0.5	-1.3	-0.7	-0.4
Commuting to job workplace: Cycle	0.1	0.1	0.5	0.3	0.2	-0.0	-0.5	0.3	0.1	0.3	0.7	-0.3	-0.5	0.6	-0.0	0.1	0.2	-0.4	0.1	0.1
Vascular/heart problems diagnosed by doctor	0.1	0.4	2.4	-0.2	-0.7	0.1	-0.4	1.6	-0.1	-1.0	-1.0	-0.1	-0.3	-0.4	-0.1	-0.1	-0.7	0.2	-0.4	-0.1
Hair Pigment	0.0	0.3	1.0	0.1	0.1	0.2	1.0	0.7	0.3	-0.4	0.0	-0.2	0.6	-0.0	0.1	0.9	0.7	0.2	0.8	0.4

Hub : Genes

NOV

Models

Trait associations