Best TWAS P=3.78e-09 · Best GWAS P=7.23e-10 conditioned to 0.00105
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | CDC123 | 0.06 | 0.04 | bslmm | 537 | 0.04 | 4.7e-14 | -5.9 | -5.2 | 2.2e-07 | 0.76 | 0.02 | 0.98 | FALSE |
| 2 | YFS | Blood | NUDT5 | 0.13 | 0.12 | enet | 40 | 0.13 | 1.1e-41 | -4.5 | -5.8 | 5.2e-09 | 0.80 | 0.95 | 0.05 | FALSE |
| 3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | NUDT5 | 0.13 | -0.01 | blup | 55 | 0.01 | 1.1e-01 | -3.7 | -5.4 | 8.3e-08 | 0.54 | 0.02 | 0.09 | FALSE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | CDC123 | 0.08 | 0.00 | blup | 64 | 0.03 | 4.0e-03 | -2.2 | -5.9 | 3.8e-09 | 0.60 | 0.01 | 0.12 | TRUE |
| 5 | The Cancer Genome Atlas | Soft Tissue Sarcoma | NUDT5 | 0.08 | 0.07 | enet | 8 | 0.07 | 8.2e-05 | -3.3 | -5.4 | 5.5e-08 | 0.56 | 0.81 | 0.07 | FALSE |