TWAS
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Traits
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Traits
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Forced vital capacity (FVC), Best measure
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chr10:11,515,875-12,989,666
Best TWAS P=3.78e-09 · Best GWAS P=7.23e-10 conditioned to 0.00105
11.6M
11.8M
12M
12.2M
12.4M
12.6M
12.8M
13M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Soft Tissue Sarcoma
CDC123
0.08
0.00
blup
64
0.03
4.0e-03
-2.2
-5.9
3.8e-09
0.60
0.01
0.12
TRUE
2
YFS
Blood
NUDT5
0.13
0.12
enet
40
0.13
1.1e-41
-4.5
-5.8
5.2e-09
0.80
0.95
0.05
FALSE
5
The Cancer Genome Atlas
Soft Tissue Sarcoma
NUDT5
0.08
0.07
enet
8
0.07
8.2e-05
-3.3
-5.4
5.5e-08
0.56
0.81
0.07
FALSE
3
The Cancer Genome Atlas
Pheochromocytoma and Paraganglioma
NUDT5
0.13
-0.01
blup
55
0.01
1.1e-01
-3.7
-5.4
8.3e-08
0.54
0.02
0.09
FALSE
1
NTR
Blood
CDC123
0.06
0.04
bslmm
537
0.04
4.7e-14
-5.9
-5.2
2.2e-07
0.76
0.02
0.98
FALSE