Best TWAS P=3.97e-08 · Best GWAS P=2.22e-08 conditioned to 0.134
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | MLLT10 | 0.06 | 0.02 | lasso | 4 | 0.03 | 0.0008 | -5.1 | 5.3 | 1.1e-07 | -0.94 | 0.04 | 0.96 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | CASC10 | 0.08 | 0.02 | lasso | 5 | 0.01 | 0.0614 | -5.5 | -5.5 | 4.0e-08 | 0.90 | 0.03 | 0.94 | TRUE |
| 3 | GTEx | Spleen | MLLT10 | 0.16 | 0.02 | lasso | 7 | 0.02 | 0.1030 | -5.5 | 5.2 | 2.0e-07 | -0.92 | 0.04 | 0.42 | FALSE |