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Forced vital capacity (FVC), Best measure
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chr10:21,087,485-22,724,472
Best TWAS P=3.97e-08 · Best GWAS P=2.22e-08 conditioned to 0.134
21M
21.2M
21.4M
21.6M
21.8M
22M
22.2M
22.4M
22.6M
22.8M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Skin Sun Exposed Lower leg
CASC10
0.08
0.02
lasso
5
0.01
0.0614
-5.5
-5.5
4.0e-08
0.90
0.03
0.94
TRUE
1
GTEx
Skin Sun Exposed Lower leg
MLLT10
0.06
0.02
lasso
4
0.03
0.0008
-5.1
5.3
1.1e-07
-0.94
0.04
0.96
FALSE
3
GTEx
Spleen
MLLT10
0.16
0.02
lasso
7
0.02
0.1030
-5.5
5.2
2.0e-07
-0.92
0.04
0.42
FALSE