Best TWAS P=1.63e-08 · Best GWAS P=1.08e-08 conditioned to 0.0489
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ZNF438 | 0.06 | 0.05 | enet | 7 | 0.03 | 4.3e-05 | -5.7 | 5.2 | 2.4e-07 | -0.97 | 0.01 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ZNF438 | 0.03 | 0.00 | blup | 123 | 0.02 | 1.8e-05 | 3.4 | 5.5 | 3.5e-08 | -0.70 | 0.05 | 0.88 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ZNF438 | 0.04 | 0.02 | lasso | 5 | 0.03 | 6.8e-04 | -5.5 | 5.6 | 1.6e-08 | -0.81 | 0.02 | 0.90 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ZNF438 | 0.09 | 0.03 | enet | 10 | 0.03 | 7.1e-05 | 3.4 | 5.2 | 1.6e-07 | -0.74 | 0.06 | 0.88 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ZNF438 | 0.06 | 0.02 | lasso | 4 | 0.02 | 1.8e-03 | -3.4 | 5.2 | 2.0e-07 | -0.83 | 0.02 | 0.95 | FALSE |