TWAS
hub
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Usage
Models
Genes
Traits
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Traits
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Forced vital capacity (FVC), Best measure
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chr10:30,435,876-32,016,090
Best TWAS P=1.63e-08 · Best GWAS P=1.08e-08 conditioned to 0.0489
30.4M
30.6M
30.8M
31M
31.2M
31.4M
31.6M
31.8M
32M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
ZNF438
0.04
0.02
lasso
5
0.03
6.8e-04
-5.5
5.6
1.6e-08
-0.81
0.02
0.90
TRUE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
ZNF438
0.03
0.00
blup
123
0.02
1.8e-05
3.4
5.5
3.5e-08
-0.70
0.05
0.88
FALSE
4
The Cancer Genome Atlas
Brain Lower Grade Glioma
ZNF438
0.09
0.03
enet
10
0.03
7.1e-05
3.4
5.2
1.6e-07
-0.74
0.06
0.88
FALSE
5
The Cancer Genome Atlas
Prostate Adenocarcinoma
ZNF438
0.06
0.02
lasso
4
0.02
1.8e-03
-3.4
5.2
2.0e-07
-0.83
0.02
0.95
FALSE
1
CommonMind
Brain Pre-frontal Cortex
ZNF438
0.06
0.05
enet
7
0.03
4.3e-05
-5.7
5.2
2.4e-07
-0.97
0.01
0.99
FALSE