Best TWAS P=5.5e-12 · Best GWAS P=2.33e-11 conditioned to 0.00734
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | CTPS1 | 0.10 | 0.00 | enet | 8 | 0.00 | 4.6e-01 | 5.0 | 5.8 | 7.7e-09 | 0.70 | 0.04 | 0.62 | FALSE |
| 2 | GTEx | Lung | CTPS1 | 0.06 | 0.04 | lasso | 3 | 0.04 | 2.4e-04 | 5.5 | 6.2 | 5.4e-10 | 0.76 | 0.20 | 0.65 | FALSE |
| 3 | GTEx | Nerve Tibial | SCMH1 | 0.16 | 0.03 | enet | 24 | 0.07 | 1.6e-05 | 5.8 | -5.3 | 1.1e-07 | -0.63 | 0.04 | 0.95 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SCMH1 | 0.03 | 0.03 | lasso | 2 | 0.02 | 6.2e-03 | 6.5 | -6.5 | 8.9e-11 | -0.91 | 0.01 | 0.92 | FALSE |
| 5 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | SCMH1 | 0.35 | 0.14 | blup | 96 | 0.14 | 1.5e-05 | -3.7 | 5.2 | 2.1e-07 | 0.50 | 0.17 | 0.29 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | SCMH1 | 0.07 | 0.08 | blup | 97 | 0.07 | 2.5e-07 | 5.7 | -6.9 | 5.5e-12 | -0.69 | 0.22 | 0.78 | TRUE |