Best TWAS P=4.16e-12 · Best GWAS P=3.59e-14 conditioned to 8.44e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CDK6 | 0.12 | 0.10 | lasso | 2 | 0.10 | 1.9e-12 | 6.9 | 6.9 | 6.4e-12 | -0.60 | 0.11 | 0.89 | FALSE |
| 2 | GTEx | Esophagus Muscularis | FAM133B | 0.07 | 0.01 | enet | 2 | 0.01 | 1.2e-01 | -6.0 | -5.5 | 2.9e-08 | 0.67 | 0.09 | 0.14 | FALSE |
| 3 | GTEx | Testis | CDK6 | 0.10 | 0.10 | lasso | 3 | 0.09 | 8.0e-05 | 6.6 | -6.9 | 4.2e-12 | 0.67 | 0.16 | 0.73 | TRUE |