[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), predicted :

chr8:130,517,157-131,045,893

Best TWAS P=3.81e-10 · Best GWAS P=1.24e-10 conditioned to 0.077

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 The Cancer Genome Atlas Bladder Urothelial Carcinoma GSDMC 0.03 0.01 blup 57 0.02 1.4e-02 -6.2 -5.8 6.4e-09 0.94 0.01 0.88 FALSE
2 The Cancer Genome Atlas Breast Invasive Carcinoma GSDMC 0.05 0.06 lasso 7 0.05 1.5e-10 -6.2 -6.0 1.6e-09 0.90 0.01 0.99 FALSE
3 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma GSDMC 0.21 0.14 blup 57 0.15 1.2e-07 -6.4 -5.4 5.1e-08 0.83 0.00 1.00 FALSE
4 The Cancer Genome Atlas Colon Adenocarcinoma GSDMC 0.13 0.08 lasso 7 0.09 5.0e-06 -5.6 -5.2 1.9e-07 0.88 0.01 0.98 FALSE
5 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma GSDMC 0.25 0.30 lasso 5 0.32 4.6e-36 -6.2 -6.0 1.9e-09 0.95 0.02 0.98 FALSE
6 The Cancer Genome Atlas Lung Squamous Cell Carcinoma GSDMC 0.16 0.14 blup 57 0.15 6.3e-17 -5.5 -5.4 7.6e-08 0.85 0.14 0.86 FALSE
7 The Cancer Genome Atlas Prostate Adenocarcinoma GSDMC 0.03 0.02 blup 57 0.02 1.4e-03 -6.2 -6.3 3.8e-10 0.91 0.01 0.92 TRUE
8 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma GSDMC 0.21 0.05 blup 57 0.06 1.2e-02 -6.4 -5.3 9.3e-08 0.86 0.01 0.82 FALSE