Best TWAS P=1.2e-09 · Best GWAS P=1.24e-14 conditioned to 1.61e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | RP11-435O5.5 | 0.09 | 0.04 | lasso | 2 | 0.02 | 0.0073 | 6.3 | -6.1 | 1.2e-09 | 0.18 | 0.25 | 0.04 | TRUE |
| 2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PTCH1 | 0.02 | 0.01 | blup | 54 | 0.02 | 0.0011 | 5.5 | -5.3 | 1.3e-07 | 0.27 | 0.06 | 0.04 | FALSE |