[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), predicted :

chr11:66,468,469-67,856,510

Best TWAS P=2.3e-17 · Best GWAS P=2.99e-17 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RAD9A 0.43 0.22 lasso 6 0.23 7.1e-19 -8.4 -8.4 5.3e-17 0.97 0 1.00 FALSE
2 GTEx Artery Tibial RAD9A 0.39 0.26 lasso 2 0.24 3.5e-19 -8.4 -8.5 2.3e-17 1.00 0 1.00 TRUE
3 GTEx Cells Transformed fibroblasts RAD9A 0.24 0.16 lasso 3 0.16 3.6e-12 -8.4 -7.7 1.1e-14 0.92 0 1.00 FALSE
4 GTEx Colon Transverse RAD9A 0.40 0.16 lasso 8 0.16 7.2e-08 -8.4 -7.4 1.8e-13 0.88 0 1.00 FALSE
5 GTEx Esophagus Muscularis RAD9A 0.25 0.26 lasso 2 0.26 6.2e-16 -8.4 -8.3 7.8e-17 0.99 0 1.00 FALSE
6 GTEx Muscle Skeletal RAD9A 0.12 0.02 lasso 4 0.03 4.2e-04 -8.4 -7.4 1.5e-13 0.83 0 0.99 FALSE
7 GTEx Nerve Tibial RAD9A 0.53 0.24 lasso 10 0.23 5.6e-16 -8.4 -8.2 1.7e-16 0.99 0 1.00 FALSE
8 GTEx Testis RAD9A 0.72 0.50 lasso 4 0.49 1.1e-24 -8.4 -8.4 6.5e-17 1.00 0 1.00 FALSE
9 GTEx Thyroid RAD9A 0.27 0.07 lasso 6 0.20 1.8e-15 -8.4 -5.9 2.9e-09 0.70 0 1.00 FALSE
10 ROSMAP Brain Pre-frontal Cortex RAD9A 0.34 0.17 enet 21 0.20 1.1e-25 -8.4 -6.8 8.1e-12 0.89 0 1.00 FALSE
11 YFS Blood RAD9A 0.08 0.02 lasso 7 0.04 5.4e-12 -8.4 -6.4 1.2e-10 0.78 0 1.00 FALSE