[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), predicted : ← →

chr12:55,677,395-57,452,308

Best TWAS P=1.92e-08 · Best GWAS P=1.18e-07 conditioned to 0.983

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CNPY2	0.06	0.05	lasso	8	0.05	2.3e-06	5.0	-5.2	2.0e-07	-0.96	0.02	0.98	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PAN2	0.05	0.07	lasso	3	0.06	5.4e-08	5.2	5.2	2.1e-07	0.90	0.02	0.98	FALSE
3	GTEx	Artery Aorta	RP11-977G19.11	0.26	0.28	lasso	14	0.28	5.3e-16	5.2	-5.2	2.1e-07	-0.90	0.02	0.97	FALSE
4	GTEx	Artery Coronary	RP11-977G19.11	0.24	0.14	lasso	13	0.08	1.2e-03	5.0	-5.3	9.2e-08	-0.90	0.03	0.95	FALSE
5	GTEx	Artery Tibial	RP11-977G19.11	0.16	0.18	lasso	12	0.18	6.1e-14	5.2	-5.2	2.1e-07	-0.90	0.02	0.97	FALSE
6	GTEx	Brain Caudate basal ganglia	RP11-977G19.11	0.31	0.25	lasso	5	0.28	1.2e-08	5.2	-5.3	1.2e-07	-0.91	0.02	0.98	FALSE
7	GTEx	Brain Cerebellum	RP11-977G19.11	0.17	0.19	lasso	14	0.18	5.4e-06	5.2	-5.2	2.1e-07	-0.93	0.02	0.96	FALSE
8	GTEx	Brain Hypothalamus	RP11-977G19.11	0.32	0.20	lasso	6	0.23	4.4e-06	5.2	-5.2	2.4e-07	-0.94	0.02	0.97	FALSE
9	GTEx	Brain Putamen basal ganglia	RP11-973D8.4	0.18	0.21	lasso	1	0.14	4.3e-04	5.2	-5.2	2.5e-07	-0.97	0.02	0.88	FALSE
10	GTEx	Cells Transformed fibroblasts	PAN2	0.09	0.07	lasso	4	0.05	1.7e-04	5.2	5.3	1.3e-07	0.96	0.02	0.97	FALSE
11	GTEx	Esophagus Gastroesophageal Junction	RP11-977G19.11	0.18	0.14	lasso	13	0.07	2.0e-03	5.2	-5.2	2.1e-07	-0.90	0.02	0.96	FALSE
12	GTEx	Liver	STAT2	0.32	0.17	lasso	13	0.14	9.9e-05	5.2	5.2	1.6e-07	0.92	0.02	0.97	FALSE
13	GTEx	Lung	RP11-977G19.11	0.07	0.03	lasso	11	0.04	5.1e-04	5.0	-5.3	9.5e-08	-0.86	0.03	0.96	FALSE
14	GTEx	Lung	CNPY2	0.05	0.03	lasso	4	0.00	1.7e-01	5.2	5.3	1.4e-07	0.97	0.02	0.93	FALSE
15	GTEx	Nerve Tibial	IL23A	0.06	0.08	lasso	10	0.07	1.6e-05	5.2	5.2	1.9e-07	0.97	0.02	0.97	FALSE
16	GTEx	Nerve Tibial	STAT2	0.08	0.05	lasso	3	0.03	5.0e-03	5.2	-5.2	2.4e-07	-0.96	0.02	0.94	FALSE
17	GTEx	Pancreas	IL23A	0.23	0.01	lasso	13	0.04	1.1e-02	5.2	5.2	1.6e-07	0.92	0.02	0.97	FALSE
18	GTEx	Pituitary	RP11-977G19.11	0.47	0.40	lasso	14	0.40	4.5e-11	5.0	-5.2	1.6e-07	-0.90	0.03	0.97	FALSE
19	GTEx	Pituitary	CNPY2	0.32	0.19	lasso	11	0.12	6.8e-04	5.2	5.2	2.1e-07	0.90	0.02	0.92	FALSE
20	GTEx	Skin Sun Exposed Lower leg	CNPY2	0.10	0.08	lasso	5	0.08	5.9e-07	5.2	5.3	1.4e-07	0.90	0.02	0.98	FALSE
21	GTEx	Thyroid	IL23A	0.07	0.04	lasso	10	0.00	1.9e-01	5.2	5.2	2.1e-07	0.90	0.02	0.93	FALSE
22	GTEx	Thyroid	RP11-977G19.11	0.16	0.11	enet	20	0.13	3.5e-10	5.0	-5.4	8.6e-08	-0.90	0.03	0.97	FALSE
23	ROSMAP	Brain Pre-frontal Cortex	NABP2	0.12	0.12	lasso	4	0.13	2.7e-16	5.2	5.2	1.8e-07	0.91	0.02	0.98	FALSE
24	YFS	Blood	CNPY2	0.02	0.02	lasso	1	0.02	5.8e-07	5.2	5.2	2.5e-07	0.96	0.02	0.98	FALSE
25	The Cancer Genome Atlas	Glioblastoma Multiforme	PAN2	0.08	0.04	blup	31	0.03	4.4e-02	5.2	5.5	4.9e-08	0.96	0.01	0.60	FALSE
26	The Cancer Genome Atlas	Lung Adenocarcinoma	STAT2	0.02	0.02	blup	21	0.01	9.6e-03	5.0	5.2	2.0e-07	0.96	0.01	0.84	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	IL23A	0.03	0.03	blup	22	0.02	1.8e-03	5.2	5.6	1.9e-08	0.94	0.01	0.81	TRUE