Hub : Genes

CNPY2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0640	0.0220	4.6e-05	0.047	0.045	0.042	0.046	0.046	1.8e-06	3.2e-06	7.1e-06	2.5e-06	2.3e-06
2	GTEx	Artery Aorta	0.1280	0.0510	1.6e-03	0.028	NA	0.033	NA	0.033	1.1e-02	NA	6.4e-03	NA	5.9e-03
3	GTEx	Lung	0.0540	0.0253	5.0e-03	0.030	NA	-0.001	NA	0.003	2.1e-03	NA	3.9e-01	NA	1.7e-01
4	GTEx	Nerve Tibial	0.0736	0.0331	3.3e-03	-0.003	NA	0.000	NA	-0.004	5.5e-01	NA	3.1e-01	NA	9.6e-01
5	GTEx	Pancreas	0.1220	0.0540	4.9e-03	0.012	NA	0.026	NA	0.018	9.5e-02	NA	2.8e-02	NA	5.8e-02
6	GTEx	Pituitary	0.3200	0.1090	8.0e-04	0.186	NA	0.058	NA	0.119	2.0e-05	NA	1.4e-02	NA	6.7e-04
7	GTEx	Skin Sun Exposed Lower leg	0.1030	0.0380	1.5e-04	0.082	NA	0.060	NA	0.077	2.4e-07	NA	1.0e-05	NA	5.9e-07
8	GTEx	Thyroid	0.0640	0.0290	3.6e-03	0.016	NA	0.015	NA	0.016	1.9e-02	NA	2.2e-02	NA	2.1e-02
9	YFS	Blood	0.0198	0.0080	1.7e-04	0.022	0.011	0.014	0.015	0.019	7.7e-08	1.1e-04	2.0e-05	7.8e-06	5.8e-07

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.1	0.1	0.5	-0.0	-0.7	0.3	0.7	-0.3	-0.1	-0.1	-0.1	-0.2
Bipolar Disorder or Schizophrenia	1.2	2.9	5.3	2.0	-1.6	-1.5	-0.8	-1.0	-1.9	-1.9	-2.0	-2.3
Depressed Affect (Nagel 2018)	2.1	4.4	6.4	2.2	-2.1	-1.8	1.4	-1.0	-2.4	-2.5	-2.4	-2.3
Depression (Nagel 2018)	0.9	1.4	1.9	1.2	-1.4	-0.8	1.4	0.4	-1.3	-1.4	-1.2	-1.1
Intelligence (Savage-Jansen 2018)	0.2	0.6	3.3	-0.2	-0.1	0.3	-1.8	-1.3	0.1	-0.0	-0.5	0.2
Neuroticism (Nagel 2018)	0.6	1.4	2.7	1.2	-1.0	-0.8	1.6	0.4	-1.3	-1.4	-1.3	-1.3
Schizophrenia (2018)	2.3	4.8	7.9	2.6	-1.6	-2.1	-1.7	-1.1	-2.4	-2.3	-2.5	-2.8
Schizophrenia vs Biploar Disorder	1.0	1.3	3.0	1.3	-0.6	-1.1	0.6	-0.2	-1.3	-1.2	-1.2	-1.7
Worry (Nagel 2018)	0.5	1.1	1.7	1.1	-0.7	-0.8	0.7	1.2	-1.1	-1.2	-1.3	-1.2
Alzheimer’s Disease (in mother)	0.5	0.6	0.9	0.8	-1.0	-1.0	0.7	-0.1	-0.9	-0.9	-0.3	-0.8
Alzheimer’s Disease (in father)	0.6	0.6	1.0	-0.8	0.5	0.5	0.9	0.7	0.9	0.9	1.0	0.8
Alzheimer’s Disease (including proxy)	0.3	0.4	1.8	-0.2	-0.2	-0.1	1.3	1.0	0.2	0.2	0.8	0.4
Crohns Disease (2017)	0.1	0.1	0.5	0.3	-0.7	0.0	-0.1	-0.0	-0.2	-0.3	-0.4	-0.4
Irritable Bowel Disease (IBD)	0.1	0.2	0.4	0.3	-0.6	-0.1	-0.6	-0.2	-0.4	-0.4	-0.6	-0.3
Ulcerative Colitis (UC)	0.1	0.1	0.7	-0.0	0.1	0.1	-0.8	-0.7	-0.1	-0.1	-0.3	0.1
Major Depression (MDD)	0.3	0.3	0.6	0.6	-0.1	-0.6	0.7	-0.7	-0.6	-0.5	-0.5	-0.6
Reaction Time	1.5	2.9	3.9	-1.8	1.5	1.7	1.3	2.0	1.8	1.9	1.6	1.6
Verbal and Numeric Reasoning (VNR)	0.4	0.9	5.3	0.3	-0.2	-0.1	-2.3	-1.2	-0.6	-0.7	-0.9	-0.3
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ovarian Cancer	0.7	1.0	2.2	-1.0	0.6	0.5	0.5	-0.7	1.5	1.5	1.2	0.9
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.7	1.1	6.0	-0.3	0.8	0.6	-2.5	1.2	0.6	0.6	0.7	0.2
Bipolar Disorder (2011)	0.1	0.1	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.7
Body Mass Index (BMI) (2010)	0.9	1.3	2.1	1.1	-0.7	-1.4	-0.7	-1.3	-1.1	-1.0	-1.4	-1.2
Coronary Artery Disease (CAD)	2.7	3.2	5.7	1.5	-1.8	-1.7	-2.4	-1.9	-1.8	-1.7	-1.5	-1.8
Crohns Disease (2012)	0.1	0.1	0.4	0.3	-0.7	0.0	0.2	0.4	-0.3	-0.4	0.1	-0.2
Mean Putamen Volume	0.5	0.6	1.3	0.8	-0.4	-1.1	-0.7	0.1	-0.9	-0.9	-0.8	-0.6
Fasting Glucose	1.4	1.6	2.0	-1.2	0.9	1.3	1.4	1.4	1.3	1.3	1.1	1.4
HbA1C	1.5	1.7	4.0	1.8	-1.1	-1.6	0.2	-2.0	-1.1	-1.0	-0.2	-1.3
HDL Cholesterol	0.6	1.0	1.6	-1.3	1.3	1.1	-0.9	0.6	0.9	0.8	0.9	1.0
LDL Cholesterol	0.2	0.3	0.8	-0.4	-0.8	0.6	0.6	0.9	0.4	0.3	0.4	0.3
Lupus	1.1	1.7	3.3	-1.8	1.0	1.8	-0.3	0.1	1.6	1.4	1.4	1.0
Neuroticism (2016)	0.4	0.6	1.4	1.2	0.2	-1.2	0.6	-0.4	-0.7	-0.7	-1.1	-0.6
Primary Biliary Cirrhosis	2.6	3.7	5.1	2.2	-2.0	-1.9	1.2	1.2	-2.2	-2.3	-1.9	-2.1
Rheumatoid Arthritis	0.2	0.3	2.1	0.0	-0.2	0.2	1.5	0.2	0.0	0.0	0.4	0.1
Schizophrenia (2014)	0.7	1.6	2.4	1.6	-0.6	-1.2	-0.9	-1.0	-1.5	-1.5	-1.4	-1.5
Triglycerides	1.3	2.2	11.5	-1.1	-0.6	1.1	3.4	0.7	1.1	1.3	0.8	1.1
Type 2 Diabetes (T2D) (2012)	0.6	0.6	2.5	-0.4	-1.6	0.3	-0.6	1.3	-0.7	-0.7	-0.2	0.2
Ulcerative Colitis	1.1	1.6	2.6	-1.3	1.6	1.3	0.9	-0.4	1.4	1.4	1.3	1.3
Blood Eosinophil Count	0.5	3.9	31.0	-0.2	-0.3	0.3	-5.6	-1.9	0.4	0.4	0.1	0.2
Blood Platelet Count	0.9	10.0	26.0	-3.0	1.2	3.1	5.1	-3.8	2.9	2.7	2.5	2.8
Blood Red Count	3.5	33.9	45.5	6.7	-5.2	-6.3	-0.9	-4.0	-6.7	-6.6	-6.6	-6.6
Blood White Count	0.5	3.8	9.2	2.0	-3.0	-1.8	0.6	-1.6	-1.9	-1.9	-1.8	-2.0
Heel T-Score	0.5	4.1	8.2	2.2	-2.9	-1.5	-1.3	-1.0	-2.2	-2.5	-1.9	-1.9
BMI	0.1	0.8	2.2	1.0	-0.2	-0.8	1.5	-0.8	-0.9	-0.8	-0.8	-1.0
Height	5.4	103.3	134.6	-11.6	9.6	11.2	6.0	6.2	11.4	11.5	10.7	11.3
Waist Hip Ratio (WHR)	0.7	3.1	4.6	-2.0	0.5	2.1	2.1	0.4	2.0	2.0	1.9	2.0
Systolic Blood Pressure	0.2	0.8	6.2	-0.1	-0.5	-0.2	2.5	-0.4	0.2	0.4	0.2	-0.0
Smoking Status	2.3	5.6	23.8	-2.1	1.5	2.0	4.9	1.4	1.9	2.1	1.8	1.8
Allergy or Eczema	0.9	2.4	9.0	-1.4	-0.2	1.1	-3.0	-1.6	1.4	1.3	1.0	1.4
Cardiovascular Disease	1.0	3.4	9.5	1.8	-1.2	-1.8	3.1	-1.2	-1.8	-1.6	-1.7	-1.6
Hypothyroidism (self reported)	1.1	2.6	9.5	1.2	-0.4	-1.2	-3.1	-2.1	-1.1	-1.4	-1.3	-1.3
Respiratory disease	1.3	2.9	19.7	-0.6	0.1	0.7	-4.4	-1.9	0.7	0.7	0.8	0.5
Type 2 Diabetes (T2D) (2018)	1.3	2.5	6.5	1.6	-1.0	-1.4	-1.0	-2.5	-1.6	-1.5	-1.7	-1.4
Lung FEV1/FVC ratio	0.5	2.6	17.8	0.0	-0.8	0.0	4.2	2.2	-0.1	-0.2	0.0	-0.1
Lung FVC	2.2	11.4	13.8	-3.4	2.8	3.2	3.7	3.6	3.3	3.3	3.6	3.4
Neuroticism	0.4	1.0	4.5	0.5	0.5	-0.3	2.1	1.4	-0.6	-0.7	-0.9	-0.6
Chronotype (morning person)	3.2	7.3	13.1	-3.1	1.2	3.1	1.3	0.6	3.1	2.9	3.6	3.5
Hair Pigment	0.1	2.8	17.6	0.0	0.3	0.1	4.2	2.8	-0.1	-0.1	0.4	-0.1
Tanning	0.6	7.1	10.9	-3.3	2.2	2.7	0.4	1.5	3.2	3.2	2.9	3.1
Hand grip strength (left)	0.3	0.9	1.3	-1.1	1.0	1.0	0.2	0.1	1.0	1.1	0.9	1.1
Number of treatments/medications taken	0.8	1.4	4.7	-1.1	0.9	1.2	2.2	-1.2	0.9	0.7	1.0	0.9
Average weekly spirits intake	2.4	2.9	6.1	1.8	-1.0	-1.5	-1.0	-2.5	-1.7	-1.7	-1.8	-1.9
Sensitivity / hurt feelings	0.2	0.3	0.8	0.6	0.1	-0.2	0.9	0.8	-0.6	-0.7	-0.2	-0.5
Frequency of depressed mood in last 2 weeks	0.4	0.6	3.5	0.4	-0.8	-0.3	1.9	0.3	-0.4	-0.5	-0.4	-0.4
Hearing difficulty/problems: Yes	0.1	0.2	1.5	0.2	0.2	-0.2	0.2	1.2	-0.2	-0.2	-0.3	-0.1
Relative age of first facial hair	0.4	0.9	1.7	1.1	-0.3	-0.9	-1.3	0.3	-1.1	-1.3	-0.9	-0.8
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.7	-0.5	0.8	0.5	0.7	-0.1	0.5	0.4	0.7	0.5
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.7	-0.5	0.8	0.7	0.2	-0.4	0.5	0.5	0.3	0.4
Ever had hysterectomy (womb removed)	0.6	0.7	1.3	-1.0	0.1	1.1	0.5	-0.3	1.0	0.8	1.1	1.0
Systolic blood pressure, automated reading	0.1	0.3	2.4	-0.0	-0.7	0.1	1.6	-0.3	0.1	0.1	0.4	0.0
Eye problems/disorders: Diabetes related eye disease	3.2	3.5	7.0	2.0	-0.8	-1.9	-2.6	-0.7	-2.1	-2.3	-1.7	-1.9
Angina	0.3	0.3	0.9	0.8	0.1	-0.5	-0.3	-0.6	-0.6	-0.6	-0.3	-0.9
Medication for hormone replacement therapy	0.1	0.1	0.3	-0.3	0.5	0.3	-0.0	0.5	0.3	0.3	-0.2	0.1
Vitamin and mineral supplements	0.7	1.0	2.1	0.8	-1.4	-0.9	-0.9	-1.3	-0.7	-0.7	-1.1	-0.6
Supplements: Zinc	2.5	2.7	3.7	-1.8	0.3	1.8	1.9	1.9	1.4	1.3	1.7	1.9
Medication: Co-codamol	0.6	0.7	1.2	-0.8	0.3	1.1	0.9	0.8	0.8	0.8	0.8	0.8
Medication: Metformin	0.2	0.3	2.0	-0.3	0.3	0.3	-0.3	-1.4	0.1	0.2	0.2	0.5
Diabetes (father)	0.4	0.5	1.7	-0.6	1.3	0.4	0.3	0.3	0.8	0.9	0.1	0.5
Diabetes (mother)	0.3	0.4	0.8	0.7	-0.7	-0.9	-0.3	0.8	-0.5	-0.6	-0.6	-0.5
Severe depression (siblings)	0.2	0.2	0.6	-0.4	0.6	0.5	0.8	0.1	0.3	0.2	0.5	0.4
Pack years adult smoking proportion	2.6	3.9	5.2	2.2	-1.7	-2.2	-1.1	-1.4	-2.1	-2.2	-2.3	-2.2
Impedance of leg (right)	0.4	1.9	7.6	0.9	-1.8	-0.9	-2.8	-0.1	-1.2	-1.1	-1.2	-0.9
Leg fat-free mass (left)	2.1	11.4	16.5	-3.4	3.6	3.3	4.1	1.2	3.6	3.6	3.4	3.3
Trunk fat percentage	0.2	0.9	1.6	1.0	-0.6	-1.2	-0.2	-1.3	-0.9	-0.9	-1.0	-1.0
Hand grip strength (right)	0.2	0.6	1.8	-0.8	-0.0	0.5	-0.1	-1.4	0.8	0.8	0.6	0.8
Townsend deprivation index at recruitment	3.2	4.4	10.7	-1.9	1.9	2.0	3.3	1.8	2.0	2.0	1.8	1.9
Current tobacco smoking	0.6	0.9	2.9	0.6	-1.4	-0.6	1.7	0.5	-0.8	-0.8	-1.0	-0.5
Average weekly fortified wine intake	0.3	0.3	1.1	-0.3	-0.9	0.3	-0.9	-1.0	0.2	0.2	0.1	0.3
Maternal smoking around birth	0.6	0.9	2.0	-0.7	1.4	0.5	1.1	1.1	0.9	0.7	1.1	0.6
Fed-up feelings	1.7	3.1	4.8	1.8	-2.2	-1.5	1.3	-1.2	-1.9	-1.9	-2.2	-1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	6.2	0.0	-0.6	-0.1	2.5	-0.4	-0.1	-0.1	-0.4	-0.0
Relative age voice broke	0.3	0.4	1.0	0.7	-0.1	-0.7	-1.0	0.1	-0.7	-0.7	-0.7	-0.5
Taking other prescription medications	0.3	0.5	1.3	-0.7	1.2	0.7	-0.1	0.1	0.7	0.5	0.9	0.6
Age when periods started (menarche)	0.3	0.8	2.1	-0.8	0.6	0.6	-1.4	-1.2	0.9	0.9	0.5	0.8
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	1.2	-0.3	-0.1	0.5	0.6	-1.1	0.2	0.2	0.4	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	5.2	1.0	-2.3	-0.6	0.8	0.6	-1.0	-1.2	-0.7	-0.9
Tinnitus: Yes, but not now, but have in the past	2.1	2.2	3.4	-1.5	1.1	1.5	1.6	-0.5	1.7	1.7	1.8	1.5
Qualifications: CSEs or equivalent	0.7	1.0	2.6	0.8	-1.6	-0.7	1.2	-0.9	-0.7	-0.6	-1.1	-0.9
Serious illness, injury or assault to yourself	4.9	6.0	8.8	2.8	-2.5	-2.6	-1.5	-1.0	-2.5	-2.6	-3.0	-2.8
High blood pressure	0.7	2.1	16.6	-0.4	0.6	0.6	4.1	0.2	0.4	0.5	0.7	0.4
Hayfever, allergic rhinitis or eczema	0.9	2.0	6.6	-1.5	-0.2	1.1	-2.6	-1.2	1.5	1.4	1.0	1.4
Multivitamins +/- minerals	0.2	0.2	0.6	-0.3	0.8	0.4	0.3	-0.6	0.3	0.2	0.5	0.2
Stomach or abdominal pain in last month	2.4	3.0	5.5	1.8	-1.1	-1.5	1.1	-0.9	-2.3	-2.4	-2.0	-1.9
Supplements: Glucosamine	1.3	1.6	4.0	-1.2	2.0	1.3	-0.0	1.5	1.3	1.1	1.3	0.9
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	1.4	-0.2	-0.3	0.3	0.6	-1.2	0.4	0.4	0.2	0.1
Medication: Atenolol	0.3	0.4	2.0	-0.3	1.4	0.5	0.5	-0.3	0.5	0.5	0.3	0.2
Medication: Levothyroxine sodium	1.1	1.9	6.6	1.2	0.0	-1.0	-2.6	-1.5	-1.1	-1.3	-1.3	-1.1
Sitting height	2.1	14.6	19.4	-4.4	3.8	4.3	2.6	1.4	4.2	4.4	3.9	4.3
Chronic bronchitis/emphysema (father)	0.5	0.6	1.4	0.8	-0.0	-0.8	-1.2	0.1	-0.9	-1.0	-0.8	-0.7
High blood pressure (mother)	0.3	0.4	2.5	-0.2	0.5	0.0	1.6	0.5	-0.0	0.0	0.3	0.6
Body mass index (BMI)	0.2	1.0	3.1	0.9	-0.4	-0.9	1.8	-1.3	-0.7	-0.7	-0.7	-0.9
Impedance of leg (left)	0.4	1.9	8.0	0.9	-1.7	-0.9	-2.8	-0.3	-1.2	-1.1	-1.2	-0.9
Leg predicted mass (left)	2.2	11.5	16.5	-3.5	3.5	3.3	4.1	1.2	3.7	3.7	3.4	3.4
Trunk fat mass	0.1	0.5	1.8	-0.5	0.7	0.3	1.4	-0.5	0.6	0.6	0.4	0.4
Waist circumference	0.5	1.7	9.4	-0.9	0.4	0.9	3.1	-0.3	1.1	1.1	0.9	0.9
Number of incorrect matches in round	1.1	1.8	2.8	-1.3	0.9	1.4	1.4	1.7	1.2	1.2	1.5	1.2
Past tobacco smoking	8.0	14.7	21.6	4.0	-3.2	-3.8	-4.6	-2.5	-3.9	-4.0	-4.2	-3.8
Alcohol usually taken with meals	0.2	0.4	1.4	-0.1	0.3	0.3	-1.2	-1.2	0.3	0.2	0.4	0.2
Nervous feelings	0.3	0.6	1.1	1.0	0.1	-0.7	0.2	1.0	-0.8	-0.9	-0.9	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.5	1.1	-1.2	-0.9	0.1	-0.3	-0.9	-1.1	-0.8	-1.1
Hearing difficulty/problems with background noise	1.9	3.0	10.2	-1.2	1.1	1.3	3.2	3.1	0.8	0.7	0.8	1.1
Hair/balding pattern: Pattern 2	0.2	0.2	1.8	-0.0	0.0	0.3	1.3	-0.2	-0.2	-0.2	0.2	0.1
Had menopause	2.1	2.7	3.4	1.8	-1.3	-1.7	-1.8	-1.2	-1.6	-1.7	-1.7	-1.7
Had other major operations	0.6	0.8	2.3	-0.9	0.7	0.6	0.2	-1.5	0.8	0.8	0.8	1.0
Forced vital capacity (FVC)	6.4	24.5	29.9	-5.5	4.8	5.1	4.3	3.5	5.3	5.5	4.9	5.4
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.6	5.3	1.2	-2.3	-0.8	0.6	0.5	-1.4	-1.6	-1.0	-1.0
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	0.9	0.7	-0.4	-0.4	0.0	-0.6	-0.7	-0.6	-0.9	-0.6
Qualifications: None of the above	3.0	6.4	13.3	-2.2	2.6	2.2	2.9	3.6	2.1	2.1	2.4	2.0
Financial difficulties in last 2 years	1.2	1.6	2.7	1.4	-1.2	-1.3	0.2	-0.5	-1.4	-1.4	-1.6	-1.6
Mouth/teeth dental problems	0.3	0.5	1.9	0.2	0.1	-0.6	-1.4	-1.3	-0.2	-0.2	-0.2	-0.2
Heart attack	1.2	1.6	2.5	1.5	-1.0	-1.3	-0.7	-0.6	-1.4	-1.4	-1.4	-1.6
Allergy	1.1	2.6	18.7	0.3	0.7	-0.2	4.3	1.9	-0.4	-0.4	-0.0	-0.3
Pain all over the body in last month	0.6	0.7	1.1	0.8	-1.1	-0.9	0.9	0.3	-0.6	-0.6	-1.1	-0.9
Diabetes (self-reported)	2.0	3.1	8.2	1.7	-1.3	-1.6	-1.4	-2.9	-1.7	-1.6	-1.6	-1.5
Hayfever/allergic rhinitis (self-reported)	1.5	2.0	3.7	-1.7	1.2	1.6	-0.3	-1.0	1.5	1.4	1.5	1.9
Medication: Ramipril	0.1	0.2	0.7	0.4	-0.2	-0.4	-0.2	-0.8	-0.3	-0.2	-0.4	-0.3
Medication: Simvastatin	2.8	4.1	6.8	2.2	-1.4	-2.2	-0.6	-2.6	-2.2	-2.2	-2.1	-2.0
Fluid intelligence score	0.4	0.9	4.1	0.6	0.5	-0.6	-2.0	-1.1	-0.7	-0.7	-0.8	-0.5
Illnesses of siblings	1.2	1.7	8.4	0.9	-1.1	-0.9	-2.9	0.5	-1.0	-0.9	-0.8	-0.9
Neuroticism score	0.4	0.8	2.7	0.7	0.0	-0.5	1.7	0.7	-0.8	-1.0	-1.0	-0.7
Weight	1.4	6.8	13.2	-2.6	2.7	2.5	3.6	0.5	2.8	2.8	2.4	2.5
Impedance of arm (right)	0.5	2.2	12.0	0.8	-1.6	-0.9	-3.5	-0.2	-1.0	-0.9	-1.1	-0.6
Arm fat percentage (right)	0.3	1.4	1.9	1.3	-1.0	-1.4	0.8	-1.0	-1.2	-1.1	-1.3	-1.3
Trunk fat-free mass	4.9	28.4	34.6	-5.6	5.2	5.6	5.9	2.6	5.7	5.8	5.4	5.4
Hip circumference	0.1	0.5	3.2	-0.4	0.7	0.3	1.8	0.0	0.5	0.6	0.3	0.5
Time employed in main current job	1.1	1.2	2.9	1.2	0.1	-1.2	-1.7	-0.7	-1.1	-1.2	-0.8	-1.2
Alcohol intake versus 10 years previously	1.6	2.3	3.2	-1.7	1.2	1.6	1.8	0.4	1.6	1.6	1.6	1.6
Father’s age at death	0.3	0.5	1.0	-0.8	0.1	0.5	0.3	-0.3	0.8	1.0	0.6	1.0
Worrier / anxious feelings	1.0	1.9	3.9	1.5	0.4	-1.2	0.2	1.5	-1.3	-1.4	-2.0	-1.7
Frequency of tiredness / lethargy in last 2 weeks	3.2	5.2	6.7	2.4	-2.3	-2.4	1.9	-1.0	-2.5	-2.5	-2.6	-2.4
Falls in the last year	2.0	2.8	6.7	1.9	-2.6	-1.6	0.4	-0.5	-1.8	-1.7	-1.4	-1.9
Hair/balding pattern: Pattern 3	0.0	0.1	0.4	-0.2	-0.2	-0.0	-0.2	0.6	0.1	0.0	-0.2	0.2
Number of live births	0.3	0.4	0.8	-0.6	0.7	0.3	0.9	0.6	0.7	0.7	0.4	0.6
Forced expiratory volume in 1-second (FEV1)	4.3	14.5	20.1	-4.0	3.5	3.6	4.5	3.2	3.9	4.0	3.7	3.9
Pulse rate	0.9	1.5	2.5	1.2	-1.5	-1.3	1.6	-1.3	-1.0	-0.9	-1.0	-1.1
Happiness	0.4	0.4	1.6	0.5	-0.8	-0.5	0.3	-1.3	-0.6	-0.5	-0.6	-0.4
Noisy workplace	0.5	0.7	3.7	-0.5	0.7	0.4	0.6	1.9	0.4	0.2	0.6	0.5
Qualifications: A levels/AS levels or equivalent	0.5	1.1	5.2	0.6	-0.2	-0.7	-2.3	-0.6	-0.8	-0.9	-1.3	-0.7
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	2.0	1.2	-1.4	-1.0	-0.9	-0.1	-1.0	-1.1	-1.1	-1.2
Mouth/teeth dental problems: Dentures	0.6	1.0	2.1	1.2	-0.4	-1.0	-0.3	-0.3	-1.2	-1.2	-1.4	-1.2
Asthma	1.7	3.3	22.4	0.3	-1.0	-0.2	-4.7	-2.5	-0.2	-0.1	-0.2	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.1	-1.0	0.5	0.9	1.1	-0.0	0.7	0.8	0.6	1.0
Medication: Cholesterol lowering	2.2	3.4	5.6	1.9	-2.4	-1.5	0.6	-2.0	-1.9	-1.8	-2.1	-1.9
Depression (self-reported)	1.6	1.9	3.2	1.5	-0.6	-1.6	0.1	-1.3	-1.5	-1.4	-1.8	-1.6
Medication: Lansoprazole	0.4	0.5	0.9	0.8	-0.0	-0.9	-0.4	-0.7	-0.7	-0.6	-0.7	-0.9
Prospective memory result	0.6	0.7	2.7	-0.7	-0.6	0.8	1.6	0.9	0.7	0.6	0.4	0.9
Lung cancer (father)	1.6	1.9	2.7	1.5	-0.4	-1.5	-0.8	1.7	-1.5	-1.5	-1.2	-1.6
Illnesses of mother	0.2	0.2	1.4	-0.1	-0.1	0.3	-1.2	0.2	0.2	0.2	-0.1	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	7.8	24.9	30.5	-5.2	4.0	5.0	5.5	4.6	5.1	5.1	5.1	5.1
Pulse wave Arterial Stiffness index	1.8	2.1	3.3	-1.6	0.1	1.7	1.8	-1.0	1.4	1.4	1.6	1.6
Impedance of arm (left)	0.6	2.8	14.2	1.1	-1.6	-1.2	-3.8	-0.2	-1.2	-1.2	-1.3	-0.9
Arm fat mass (right)	0.2	0.7	5.1	-0.3	0.5	0.2	2.3	-0.4	0.4	0.5	0.2	0.3
Trunk predicted mass	5.0	28.3	34.6	-5.6	5.1	5.6	5.9	2.5	5.7	5.8	5.4	5.4
Standing height	5.1	51.0	65.6	-8.1	7.1	7.8	4.7	4.0	8.0	8.0	7.3	7.9
Length of working week for main job	0.0	0.0	0.2	0.1	-0.2	0.1	-0.1	-0.4	-0.1	-0.2	-0.1	-0.1
Exposure to tobacco smoke at home	0.3	0.3	1.3	-0.4	1.1	0.2	-0.0	-0.1	0.6	0.6	0.4	0.5
Breastfed as a baby	0.1	0.1	0.7	-0.3	0.2	0.3	-0.3	-0.8	0.1	0.2	0.0	0.3
Tense / ‘highly strung’	0.2	0.3	0.9	0.5	-0.2	-0.3	0.9	0.4	-0.6	-0.7	-0.3	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	7.0	-1.4	0.5	1.5	2.7	0.4	1.1	1.2	0.4	1.2
Hair/balding pattern: Pattern 4	4.5	11.0	16.4	-4.0	2.5	3.9	0.9	0.6	3.8	3.8	3.8	3.9
Birth weight of first child	0.2	0.4	2.0	-0.4	0.7	0.5	-1.4	0.3	0.4	0.2	-0.0	0.3
Peak expiratory flow (PEF)	0.5	1.2	2.6	-1.1	1.6	0.8	0.4	1.0	1.2	1.3	1.0	1.0
Pulse wave reflection index	1.0	1.2	1.8	-1.2	0.9	1.3	1.3	0.5	1.0	0.9	1.4	1.2
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.6	-0.4	0.8	0.6	-0.0	0.0	0.2	0.2	0.1	0.6
Loud music exposure frequency	0.6	0.6	1.2	0.7	-1.1	-1.0	-0.2	0.4	-0.9	-0.9	-0.7	-0.7
Qualifications: O levels/GCSEs or equivalent	1.3	2.1	4.3	1.3	-1.2	-1.2	-1.8	-2.1	-1.2	-1.1	-1.7	-1.2
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	1.9	-0.6	-0.0	0.8	0.7	1.4	0.8	0.8	1.1	0.6
Blood clot in the leg (DVT)	0.2	0.2	1.1	0.1	0.6	-0.1	0.6	-1.1	-0.1	-0.2	0.2	0.0
Medication: Paracetamol	0.3	0.5	4.1	0.2	0.2	-0.1	2.0	-0.2	-0.2	-0.2	0.2	-0.4
Headache pain in last month	1.1	1.9	14.3	0.1	0.4	-0.4	3.8	1.4	-0.3	-0.3	-0.2	-0.1
Medication for cholesterol, blood pressure or diabetes	1.0	1.7	7.7	1.1	-0.7	-1.3	-2.8	-0.1	-1.0	-1.0	-1.0	-1.0
Glaucoma (self-reported)	4.5	5.3	7.7	-2.7	2.7	2.5	0.8	0.6	2.4	2.4	2.8	2.6
Gout (self-reported)	2.3	3.2	4.5	-2.0	0.8	1.9	2.1	1.3	1.8	1.7	2.1	1.9
Hypothyroidism/myxoedema (self-reported)	0.8	1.7	7.3	1.0	0.3	-0.9	-2.7	-1.3	-0.9	-1.1	-0.9	-1.0
Medication: Amlodipine	1.6	2.3	3.9	-1.5	1.5	1.5	2.0	-0.7	1.6	1.7	1.4	1.4
Medication: Ventolin 100micrograms inhaler	1.9	2.4	7.1	1.1	-1.5	-1.0	-2.2	-2.7	-1.1	-1.0	-1.3	-1.2
Birth weight	0.3	0.6	1.0	-1.0	0.9	0.4	-1.0	0.3	0.9	0.8	0.3	0.7
Chronic bronchitis/emphysema (mother)	1.9	2.2	3.5	-1.9	1.1	1.5	1.0	-0.9	1.7	1.7	1.5	1.8
High blood pressure (siblings)	1.3	1.9	10.2	-0.8	1.0	0.6	3.2	0.8	1.2	1.1	0.8	0.9
Forced vital capacity (FVC), Best measure	9.3	34.1	40.9	-6.4	4.8	6.2	5.0	4.8	6.3	6.3	6.2	6.3
Body fat percentage	0.5	1.9	2.6	1.6	-1.1	-1.6	-0.0	-1.4	-1.4	-1.4	-1.5	-1.6
Leg fat percentage (right)	0.8	3.0	4.0	2.0	-1.6	-1.9	0.1	-1.6	-1.8	-1.8	-1.9	-2.0
Arm fat-free mass (right)	3.3	17.2	23.3	-4.3	4.1	4.3	4.8	1.3	4.5	4.5	4.2	4.1
Exposure to tobacco smoke outside home	0.4	0.6	3.4	-0.0	0.5	0.2	1.8	1.2	0.2	0.2	0.2	0.0
Comparative body size at age 10	0.4	1.1	4.2	1.0	-0.8	-0.7	-0.7	-2.0	-0.8	-1.0	-1.0	-0.9
Number of full brothers	0.5	0.6	2.1	0.4	-0.7	-0.3	1.5	1.4	-0.2	-0.2	-0.5	-0.4
Worry too long after embarrassment	0.5	0.9	1.4	0.9	-0.7	-0.8	-1.0	0.6	-1.0	-1.0	-1.2	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	1.1	-0.1	-0.1	0.0	1.1	-0.1	0.1	0.1	-0.0	0.0
Wheeze or whistling in the chest in last year	0.1	0.3	1.9	-0.0	-0.3	0.2	-0.3	-1.4	-0.1	-0.2	0.3	-0.0
Number of children fathered	11.8	13.3	16.1	-4.0	3.7	4.0	3.4	1.8	4.0	4.0	3.6	3.8
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.5	10.2	0.1	0.8	-0.4	-3.2	-1.4	-0.2	-0.3	-0.3	-0.1
Age at first live birth	0.8	1.4	5.2	0.8	-0.6	-0.6	-2.3	-1.3	-1.2	-1.0	-1.1	-0.8
Pulse wave peak to peak time	1.1	1.3	2.4	1.1	0.2	-1.2	-1.6	1.3	-1.0	-1.0	-1.2	-1.2
Health satisfaction	2.4	3.2	4.8	1.8	-2.2	-1.5	-0.5	-2.0	-1.8	-1.8	-2.0	-1.8
Shortness of breath walking on level ground	2.3	2.7	3.7	1.8	-1.6	-1.8	-1.0	-0.8	-1.9	-1.6	-1.9	-1.9
Qualifications: College or University degree	0.4	1.2	9.9	-0.2	0.0	0.2	-3.1	-0.9	0.3	0.3	-0.1	0.2
Eye problems/disorders: None of the above	0.1	0.1	0.4	-0.1	0.6	-0.2	0.2	0.1	0.0	0.1	-0.2	0.2
Mouth/teeth dental problems: Loose teeth	0.4	0.5	2.8	0.5	0.0	-0.3	-0.8	1.7	-0.5	-0.5	-0.2	-0.4
Emphysema/chronic bronchitis	0.3	0.3	0.7	0.7	-0.3	-0.5	-0.4	-0.8	-0.3	-0.3	-0.8	-0.7
Medication for pain relief, constipation, heartburn	0.5	0.9	1.7	-0.8	0.5	0.8	-1.1	1.3	0.9	0.9	0.8	1.0
Neck or shoulder pain in last month	0.5	0.7	6.5	-0.0	0.0	0.0	2.6	0.0	-0.1	-0.0	0.1	-0.2
Medication: Blood pressure	3.1	5.5	11.7	-2.3	2.0	2.4	3.4	1.5	2.3	2.3	2.4	2.2
Angina (self-reported)	0.3	0.4	0.8	0.8	0.3	-0.5	-0.6	-0.6	-0.6	-0.6	-0.3	-0.9
Migraine (self-reported)	1.6	1.9	4.5	-1.4	0.8	1.1	2.1	1.7	1.2	1.2	1.3	1.2
Medication: Ibuprofen	1.1	1.3	2.2	-1.4	0.6	1.2	1.3	-1.0	1.1	1.1	0.9	1.5
Medication: Allopurinol	3.7	5.0	6.7	-2.6	0.7	2.6	2.5	1.4	2.2	2.1	2.6	2.6
Medication: Omeprazole	0.1	0.1	0.7	0.2	0.3	-0.2	0.8	-0.4	-0.1	-0.2	0.1	-0.3
Medication: Seretide 50 evohaler	2.1	2.4	9.0	1.2	-1.5	-1.0	-3.0	-1.3	-1.2	-1.3	-1.2	-1.3
Mean time to correctly identify matches	1.6	3.1	4.3	-1.9	1.6	1.7	1.5	1.6	2.0	2.1	1.6	1.7
Heart disease (mother)	0.5	0.6	1.2	-0.7	1.1	0.8	0.6	-0.3	0.7	0.7	1.0	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	0.6	-0.6	-0.2	0.4	-0.6	-0.0	0.8	0.6	0.7	0.7
Whole body fat mass	0.2	0.6	3.2	-0.5	0.8	0.4	1.8	-0.5	0.6	0.7	0.4	0.4
Leg fat mass (right)	0.1	0.4	3.4	0.0	0.4	-0.0	1.8	-0.6	0.2	0.2	0.1	-0.1
Arm predicted mass (right)	2.6	13.2	21.9	-3.7	3.5	3.7	4.7	1.2	3.9	3.9	3.7	3.5
Pulse rate, automated reading	1.3	4.2	6.2	1.9	-2.1	-2.0	2.5	-2.1	-2.0	-2.0	-1.9	-1.9
Alcohol intake frequency.	1.0	2.4	6.4	1.5	-1.6	-1.4	2.5	-0.1	-1.5	-1.3	-1.5	-1.5
Comparative height size at age 10	2.1	11.6	15.8	-3.6	4.0	3.5	2.9	2.8	3.4	3.4	3.5	3.5
Number of full sisters	0.6	0.7	3.7	-0.7	0.1	0.6	1.9	0.1	0.6	0.6	0.8	0.7
Suffer from ‘nerves’	0.7	1.1	2.2	-1.0	0.9	1.1	1.5	1.2	0.9	0.8	1.0	0.8
Overall health rating	2.2	4.7	6.4	2.4	-2.5	-1.8	1.8	-0.1	-2.5	-2.4	-2.4	-2.4
Chest pain or discomfort	1.0	1.5	2.3	1.4	-1.0	-1.2	0.3	-0.5	-1.5	-1.5	-1.4	-1.5
Had major operations	2.7	3.2	4.4	-1.9	2.1	1.9	1.0	1.5	1.8	1.7	2.0	1.9
Age at last live birth	0.4	0.6	1.9	0.6	-0.4	-0.7	-1.4	-1.1	-0.7	-0.5	-0.7	-0.5
Family relationship satisfaction	3.0	3.6	6.2	-2.1	1.4	1.9	2.5	0.5	2.1	2.2	1.7	2.0
Leg pain on walking	0.3	0.3	2.1	-0.2	-0.2	0.2	0.6	1.4	0.2	0.2	0.2	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	2.1	1.1	-0.6	-1.4	0.4	-0.9	-0.9	-0.8	-0.9	-1.3
Commuting to job workplace: Car/motor vehicle	1.8	2.0	3.0	1.6	-1.5	-1.7	-0.9	-0.5	-1.6	-1.7	-1.1	-1.7
Illness, injury, bereavement, stress in last 2 years	3.8	4.6	6.9	-2.5	2.3	2.1	-0.4	0.3	2.5	2.6	2.5	2.5
Medication: Aspirin	0.6	0.8	1.3	0.9	-0.8	-0.6	1.0	-1.1	-0.8	-0.8	-0.8	-0.9
Supplements: Vitamin C	0.5	0.6	4.0	0.1	0.5	-0.1	-0.8	2.0	-0.2	-0.3	0.1	-0.2
Knee pain experienced in last month	0.6	0.9	2.1	-1.0	0.9	1.4	-0.5	-0.0	0.9	0.9	0.8	1.0
Hypertension (Self-reported)	0.8	2.1	15.9	-0.5	0.8	0.7	4.0	0.1	0.5	0.6	0.8	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	2.0	1.3	-0.3	-1.2	0.5	-0.4	-1.4	-1.4	-1.1	-1.2
Illnesses of father: Heart disease	1.3	1.8	4.4	1.1	-1.3	-0.8	-1.6	-2.1	-1.3	-1.3	-1.0	-1.1
Illnesses of siblings: Diabetes	0.4	0.5	1.1	0.6	0.5	-0.5	0.7	-1.0	-0.7	-0.6	-1.0	-0.6
Smoking status: Previous	5.7	8.5	12.4	-3.0	2.7	2.8	3.5	1.9	3.0	3.1	3.2	2.6
Forced expiratory volume in 1-second (FEV1), predicted	10.7	22.3	27.8	-5.2	3.2	5.3	4.6	3.2	5.2	5.3	4.9	5.2
Whole body fat-free mass	3.7	21.4	27.7	-4.8	4.6	4.7	5.3	2.0	5.0	5.0	4.7	4.7
Leg fat-free mass (right)	2.3	12.0	16.9	-3.6	3.6	3.4	4.1	1.2	3.8	3.8	3.5	3.4
Arm fat percentage (left)	0.6	2.4	3.2	1.8	-1.4	-1.8	0.3	-1.4	-1.6	-1.6	-1.7	-1.8
Average weekly red wine intake	1.5	2.3	3.1	1.6	-1.2	-1.4	-1.6	-0.8	-1.7	-1.8	-1.5	-1.5
Handedness (chirality/laterality): Left-handed	1.4	1.7	2.6	1.6	-0.9	-1.5	0.1	-0.5	-1.6	-1.6	-1.6	-1.5
Mood swings	0.7	1.2	5.3	0.8	-0.7	-0.8	2.3	-0.7	-1.0	-1.1	-0.9	-0.7
Loneliness, isolation	1.1	1.5	5.0	1.0	-1.6	-0.6	2.2	0.5	-1.1	-1.2	-0.9	-1.1
Long-standing illness, disability or infirmity	0.5	0.7	1.8	0.8	-1.3	-0.5	-0.0	-0.8	-0.9	-1.0	-0.8	-0.8
Ever had bowel cancer screening	3.5	4.1	5.9	-2.1	2.0	2.2	1.6	-0.2	2.4	2.4	2.2	2.2
Diabetes diagnosed by doctor	1.3	2.2	6.4	1.4	-1.2	-1.4	-0.5	-2.5	-1.4	-1.3	-1.4	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	4.8	5.1	7.9	-2.5	0.9	2.4	2.7	0.9	2.3	2.4	2.8	2.5
Friendships satisfaction	2.4	2.9	4.2	2.0	-1.7	-2.0	-1.2	-0.9	-1.8	-1.8	-1.8	-1.9
Qualifications: nursing, teaching	0.7	1.1	2.9	-0.9	1.4	1.0	-0.2	1.7	0.8	0.9	0.6	0.8
Commuting to job workplace: Walk	0.2	0.2	0.8	-0.3	-0.7	0.3	0.2	-0.9	0.3	0.3	0.3	0.5
Eye problems/disorders: Cataract	0.2	0.2	1.7	0.4	-1.3	-0.2	-0.1	-0.0	-0.2	-0.2	-0.1	-0.3
Mouth/teeth dental problems: Mouth ulcers	2.6	4.1	10.0	-2.0	1.1	2.4	3.2	1.4	1.8	1.8	1.9	2.0
Medication for cholesterol	0.5	0.7	3.2	-0.8	-0.3	0.7	-1.8	0.7	0.5	0.6	0.6	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.6	-0.3	0.1	0.3	0.0	-0.8	0.5	0.6	0.4	0.2
Back pain experienced in last month	0.4	0.6	4.7	0.1	-0.6	0.4	2.2	0.4	-0.4	-0.3	-0.5	-0.2
Mineral and other dietary supplements	0.6	0.8	2.1	0.9	-1.5	-1.0	-0.3	-0.7	-0.8	-0.7	-0.7	-0.9
Breast cancer (self-reported)	0.2	0.3	0.6	0.5	-0.4	-0.7	0.1	-0.5	-0.6	-0.8	-0.3	-0.6
Asthma (self-reported)	1.6	3.1	21.3	-0.0	-0.8	0.2	-4.6	-2.4	0.1	0.1	0.1	-0.0
Osteoporosis (self-reported)	0.1	0.1	0.3	0.2	0.0	0.0	-0.4	0.1	-0.5	-0.5	0.2	-0.1
Osteoarthritis (self-reported)	0.1	0.2	0.6	-0.2	0.1	0.4	-0.6	-0.8	0.4	0.3	0.4	0.2
Medication: Aspirin	0.9	1.2	1.5	1.2	-1.1	-0.9	0.9	-1.0	-1.1	-1.1	-1.2	-1.2
Medication: Gliclazide	1.4	1.6	2.2	-1.2	0.8	1.3	1.5	-0.7	1.3	1.4	1.4	1.3
Illnesses of father: None of the above (group 1)	0.1	0.2	0.7	-0.0	-0.4	-0.1	-0.9	0.7	0.1	0.1	0.3	-0.1
Smoking status: Current	0.5	0.8	5.4	-0.0	-1.0	-0.0	2.3	0.8	-0.2	-0.2	-0.4	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.8	4.2	-1.1	0.8	1.0	2.0	2.0	1.1	1.1	1.0	1.3
Whole body water mass	3.6	20.4	27.1	-4.7	4.6	4.6	5.2	1.9	4.9	4.9	4.5	4.5
Leg predicted mass (right)	2.3	12.2	16.6	-3.6	3.6	3.5	4.1	1.2	3.8	3.8	3.5	3.5
Arm fat mass (left)	0.1	0.5	4.2	-0.1	0.4	0.0	2.0	-0.6	0.3	0.3	0.1	0.1
Number of self-reported non-cancer illnesses	0.7	1.3	2.5	-1.2	0.8	1.3	1.6	-1.1	1.0	1.0	1.0	1.1
Average weekly champagne plus white wine intake	0.3	0.5	2.1	-0.0	0.1	-0.2	-1.4	-1.4	0.4	0.3	-0.0	0.2
Miserableness	0.6	1.0	1.6	1.1	-0.7	-0.9	0.7	-1.0	-1.1	-1.2	-1.3	-1.1
Guilty feelings	5.2	7.9	18.9	-2.9	1.9	3.0	4.3	1.8	2.6	2.6	2.7	2.8
Wears glasses or contact lenses	1.5	1.7	4.1	-1.2	2.0	1.6	-0.6	0.6	1.3	1.3	1.4	1.1
Ever taken oral contraceptive pill	0.2	0.3	1.4	0.1	0.4	-0.1	-0.8	1.2	-0.0	-0.0	0.0	-0.2
Hearing aid user	0.4	0.4	2.0	-0.4	-1.4	0.5	0.3	-0.8	0.4	0.3	0.6	0.5
Mother’s age at death	0.4	0.5	1.2	-0.8	0.2	1.1	0.2	-0.3	0.5	0.7	0.9	1.0
Financial situation satisfaction	2.9	3.6	5.3	2.3	-1.1	-2.1	-1.1	-1.3	-2.2	-2.2	-2.0	-2.2
Tinnitus: Yes, now most or all of the time	1.7	2.0	3.3	1.4	-1.2	-1.4	-1.4	-0.0	-1.6	-1.7	-1.8	-1.4
Commuting to job workplace: Public transport	0.4	0.5	2.6	-0.4	0.6	0.6	-0.6	-1.6	0.2	0.2	0.3	0.6
Eye problems/disorders: Glaucoma	2.1	2.5	3.8	-1.9	1.6	1.7	0.5	0.0	1.8	1.8	1.8	1.7
Medication: Blood pressure	0.3	0.6	3.3	0.4	-0.1	-0.2	1.8	-1.3	-0.1	-0.1	-0.2	-0.3
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.1	-0.3	0.3	0.3	0.2	0.2	0.1	0.1	0.4	0.2
Supplements: Fish oil (including cod liver oil)	2.2	2.8	4.0	-1.8	2.0	1.7	1.9	0.8	1.8	1.7	1.4	1.7
High cholesterol (Self-reported)	1.7	3.0	3.7	1.7	-1.8	-1.6	1.9	-1.6	-1.9	-1.8	-1.6	-1.7
Medication: Bendroflumethiazide	0.3	0.5	2.8	-0.3	1.1	0.1	1.7	0.0	0.1	0.1	0.2	0.3
Medication: Paracetamol	0.5	0.7	4.1	0.4	-0.1	-0.2	2.0	-1.1	-0.5	-0.5	-0.1	-0.5
Medication: Lisinopril	1.5	2.0	2.9	-1.4	1.7	1.4	1.7	0.4	1.3	1.4	1.4	1.5
Medication: Atorvastatin	2.2	2.7	4.0	1.9	-2.0	-1.6	0.6	-0.6	-1.9	-1.8	-1.6	-1.9
Illnesses of father: High blood pressure	2.1	2.5	4.5	-1.7	0.5	1.5	2.1	1.4	1.7	1.8	1.5	1.6
Alcohol drinker status: Never	0.0	0.0	0.1	0.2	-0.0	-0.2	-0.1	0.2	-0.2	-0.2	-0.2	0.1
Ever smoked	5.3	9.3	17.7	-3.1	2.8	2.9	4.2	1.5	3.0	3.0	3.3	3.0
Basal metabolic rate	3.0	16.7	24.8	-4.2	4.1	4.1	5.0	1.7	4.4	4.4	4.0	4.0
Leg fat percentage (left)	0.7	2.7	3.3	1.8	-1.4	-1.8	0.2	-1.8	-1.7	-1.7	-1.8	-1.8
Arm fat-free mass (left)	3.1	15.8	25.1	-4.1	4.0	4.0	5.0	1.3	4.2	4.2	3.9	3.9
Number of operations (self-reported)	1.1	1.7	2.3	-1.5	1.0	1.4	1.3	-0.6	1.3	1.2	1.5	1.5
Average weekly beer plus cider intake	2.3	3.4	5.7	-2.1	0.6	2.2	0.2	1.7	2.1	2.0	2.4	2.0
Irritability	0.1	0.2	1.2	-0.0	1.1	0.0	-0.6	0.7	-0.1	-0.2	-0.1	-0.0
Risk taking	4.6	6.7	10.2	-2.8	2.5	2.8	1.3	0.7	3.1	3.2	3.0	2.7
Ever had prostate specific antigen (PSA) test	5.7	6.5	8.2	-2.8	2.4	2.9	2.6	1.9	2.7	2.6	2.3	2.7
Fractured/broken bones in last 5 years	0.4	0.5	1.8	0.6	-0.6	-0.6	0.2	-1.4	-0.6	-0.5	-0.4	-0.7
Age started oral contraceptive pill	2.9	3.7	10.1	2.0	-0.8	-1.8	-3.2	-1.7	-1.6	-1.7	-1.6	-2.0
Diastolic blood pressure, automated reading	0.5	1.5	11.6	0.3	-1.1	-0.4	3.4	-0.1	-0.2	-0.2	-0.2	-0.4
Ever depressed for a whole week	0.8	1.0	1.8	1.2	-0.5	-1.1	-0.5	0.3	-1.2	-1.1	-1.3	-1.1
Unable to work because of sickness or disability	0.5	0.6	1.9	0.5	-1.4	-0.4	0.5	-1.3	-0.8	-0.7	-0.5	-0.5
Commuting to job workplace: Cycle	0.3	0.3	1.2	-0.4	0.3	0.5	-1.1	-1.0	0.3	0.3	0.2	0.4
Myopia	0.4	0.6	1.4	0.7	-1.0	-0.3	-1.2	0.6	-0.7	-0.6	-0.7	-0.7
Vascular/heart problems diagnosed by doctor	0.6	1.6	13.2	0.1	-1.0	-0.3	-3.6	-0.2	-0.2	-0.3	-0.5	-0.1
Cholesterol lowering medication	1.7	2.4	3.6	1.9	-1.0	-1.8	0.4	-1.8	-1.8	-1.8	-1.3	-1.7
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	0.7	0.7	0.3	-0.8	0.7	-0.4	-0.7	-0.8	-0.5	-0.6
Pain experienced in last month	0.7	1.2	8.2	0.3	-0.8	-0.3	-2.9	-1.3	0.1	0.0	0.1	-0.1
Supplements: Calcium	1.5	1.6	2.6	-1.4	1.0	1.5	0.8	0.8	1.3	1.3	1.6	1.5
Basal cell carcinoma (self-reported)	2.0	2.4	5.7	-1.6	2.4	1.7	1.0	0.0	1.5	1.6	1.3	1.5
Heart attack/myocardial infarction (self-reported)	0.9	1.1	1.9	1.3	-0.7	-1.1	-0.6	-0.5	-1.2	-1.1	-1.2	-1.4
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	1.6	0.1	0.2	-0.2	0.3	-1.3	-0.2	-0.4	0.2	0.0
Heart disease (siblings)	0.3	0.4	3.5	-0.1	0.2	0.5	1.9	-0.0	0.0	-0.0	0.2	0.1
Alcohol drinker status: Previous	0.1	0.1	0.3	0.2	-0.0	-0.3	0.1	-0.6	0.1	0.4	-0.3	-0.3
Pack years of smoking	1.9	2.7	3.8	1.9	-1.2	-1.9	-1.1	-0.9	-1.7	-1.9	-1.9	-1.9
Impedance of whole body	0.7	3.4	14.7	1.3	-2.0	-1.4	-3.8	-0.4	-1.5	-1.5	-1.6	-1.2
Leg fat mass (left)	0.1	0.5	3.6	-0.1	0.5	0.1	1.9	-0.7	0.3	0.3	0.2	0.0
Arm predicted mass (left)	2.8	14.4	23.3	-3.9	3.8	3.8	4.8	1.5	4.0	4.0	3.7	3.7