Best TWAS P=1.6e-09 · Best GWAS P=6.22e-16 conditioned to 6.49e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | HIST2H2AA3 | 0.22 | 0.02 | enet | 20 | 0.12 | 1.8e-09 | 7.1 | 5.9 | 3.3e-09 | 0.70 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Tibial | RP11-196G18.22 | 0.25 | 0.05 | lasso | 5 | 0.07 | 1.8e-06 | 4.6 | 6.0 | 1.6e-09 | 0.78 | 0.01 | 0.98 | TRUE |
| 3 | GTEx | Artery Tibial | RP11-196G18.24 | 0.31 | 0.08 | enet | 26 | 0.10 | 6.1e-08 | 7.1 | 5.3 | 9.3e-08 | 0.72 | 0.00 | 0.99 | FALSE |