Best TWAS P=5.1e-16 · Best GWAS P=7.2e-16 conditioned to 0.0675
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TSEN15 | 0.23 | 0.18 | lasso | 9 | 0.18 | 4.7e-21 | 8.1 | 8.1 | 7.7e-16 | 1.00 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Brain Cerebellar Hemisphere | TSEN15 | 0.38 | 0.08 | lasso | 13 | 0.16 | 5.3e-05 | 8.1 | 8.1 | 5.1e-16 | 0.89 | 0.01 | 0.98 | TRUE |
| 3 | METSIM | Adipose | TSEN15 | 0.06 | 0.02 | enet | 28 | 0.04 | 1.3e-06 | 8.1 | 6.8 | 8.5e-12 | 0.81 | 0.00 | 1.00 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TSEN15 | 0.11 | 0.08 | blup | 52 | 0.10 | 6.7e-12 | 8.1 | 7.8 | 6.8e-15 | 0.84 | 0.00 | 1.00 | FALSE |