Best TWAS P=2.22e-08 · Best GWAS P=4.42e-08 conditioned to 0.0206
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pituitary | CNKSR1 | 0.38 | 0.16 | lasso | 7 | 0.15 | 1.4e-04 | 5.1 | -5.6 | 2.2e-08 | -0.67 | 0.07 | 0.79 | TRUE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | CNKSR1 | 0.15 | 0.10 | lasso | 7 | 0.09 | 1.0e-05 | 5.0 | -5.6 | 2.3e-08 | -0.65 | 0.04 | 0.96 | FALSE |
| 3 | GTEx | Thyroid | CNKSR1 | 0.10 | 0.04 | lasso | 7 | 0.03 | 2.1e-03 | 4.9 | -5.4 | 6.7e-08 | -0.57 | 0.02 | 0.98 | FALSE |
| 4 | METSIM | Adipose | RPS6KA1 | 0.04 | 0.01 | bslmm | 367 | 0.03 | 3.9e-05 | 4.9 | 5.6 | 2.8e-08 | 0.46 | 0.07 | 0.92 | FALSE |
| 5 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | TRIM63 | 0.03 | 0.02 | blup | 33 | 0.02 | 4.6e-03 | 4.5 | 5.2 | 2.2e-07 | 0.86 | 0.02 | 0.66 | FALSE |