Best TWAS P=1.1e-12 · Best GWAS P=1.14e-13 conditioned to 0.0176
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | CAMK1D | 0.28 | 0.24 | enet | 25 | 0.24 | 2.3e-18 | -5.1 | -5.6 | 2.0e-08 | 0.58 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Whole Blood | CAMK1D | 0.14 | 0.01 | enet | 26 | 0.04 | 2.5e-04 | -5.1 | -5.3 | 1.0e-07 | 0.68 | 0.11 | 0.85 | FALSE |
| 3 | NTR | Blood | CAMK1D | 0.10 | 0.09 | bslmm | 900 | 0.08 | 4.4e-25 | -5.1 | -5.6 | 1.7e-08 | 0.66 | 1.00 | 0.00 | FALSE |
| 4 | NTR | Blood | CDC123 | 0.06 | 0.04 | bslmm | 537 | 0.04 | 4.7e-14 | -7.3 | -7.1 | 1.1e-12 | 0.89 | 0.00 | 1.00 | TRUE |
| 5 | YFS | Blood | CAMK1D | 0.27 | 0.23 | bslmm | 875 | 0.26 | 7.7e-86 | -5.1 | -6.1 | 1.4e-09 | 0.68 | 1.00 | 0.00 | FALSE |
| 6 | YFS | Blood | CDC123 | 0.08 | 0.03 | enet | 35 | 0.06 | 9.6e-19 | -5.1 | -6.2 | 6.6e-10 | 0.68 | 0.13 | 0.87 | FALSE |
| 7 | YFS | Blood | NUDT5 | 0.13 | 0.12 | enet | 40 | 0.13 | 1.1e-41 | -5.1 | -6.1 | 1.2e-09 | 0.77 | 1.00 | 0.00 | FALSE |
| 8 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CDC123 | 0.26 | 0.07 | lasso | 4 | 0.07 | 1.4e-03 | -4.8 | 5.8 | 6.4e-09 | -0.69 | 0.10 | 0.18 | FALSE |