Best TWAS P=1.14e-09 · Best GWAS P=9.58e-07 conditioned to 0.296
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | CLUAP1 | 0.42 | 0.32 | enet | 35 | 0.35 | 1.2e-29 | -3.7 | -5.2 | 1.8e-07 | 0.70 | 0.19 | 0.55 | FALSE |
| 2 | GTEx | Esophagus Mucosa | RP11-461A8.4 | 0.11 | 0.03 | enet | 15 | 0.00 | 2.9e-01 | 3.5 | 5.6 | 2.4e-08 | -0.20 | 0.04 | 0.06 | TRUE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | CLUAP1 | 0.30 | 0.13 | enet | 18 | 0.23 | 8.1e-13 | -4.1 | -6.1 | 1.1e-09 | 0.70 | 0.07 | 0.84 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DNASE1 | 0.09 | 0.00 | enet | 12 | 0.05 | 3.4e-06 | 3.1 | -5.7 | 1.6e-08 | 0.51 | 0.00 | 0.11 | FALSE |