TWAS hub - DNASE1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0710	0.0260	2.3e-03	0.020	0.012	0.024	0.019	0.025	1.4e-03	1.2e-02	5.5e-04	2.0e-03	4.6e-04
2	GTEx	Pancreas	0.3280	0.0860	2.1e-05	0.079	NA	0.109	NA	0.133	3.1e-04	NA	2.4e-05	NA	3.1e-06
3	METSIM	Adipose	0.0679	0.0286	3.0e-03	0.008	0.007	0.002	0.009	0.003	1.6e-02	2.4e-02	1.5e-01	1.4e-02	8.7e-02
4	ROSMAP	Brain Pre-frontal Cortex	0.1316	0.0365	4.5e-06	0.062	0.049	0.049	0.067	0.063	2.2e-08	5.7e-07	6.4e-07	5.2e-09	1.5e-08
5	TCGA	Breast Invasive Carcinoma	0.0533	0.0260	7.7e-04	0.003	0.007	0.010	NA	0.000	5.7e-02	1.0e-02	3.2e-03	NA	2.9e-01
6	TCGA	Kidney Renal Papillary Cell Carcinoma	0.2440	0.0880	4.0e-04	0.038	0.085	0.087	NA	0.048	3.0e-03	1.4e-05	1.1e-05	NA	9.3e-04
7	TCGA	Brain Lower Grade Glioma	0.0940	0.0454	1.1e-03	0.000	0.044	0.048	NA	0.005	3.2e-01	8.0e-06	3.4e-06	NA	8.0e-02
8	TCGA	Liver Hepatocellular Carcinoma	0.2050	0.0940	7.7e-05	0.104	0.102	0.099	NA	0.107	1.4e-05	1.6e-05	2.2e-05	NA	9.9e-06
9	TCGA	Pancreatic Adenocarcinoma	0.0990	0.0540	7.7e-03	0.025	0.060	0.031	NA	0.019	3.0e-02	1.7e-03	1.8e-02	NA	5.1e-02
10	TCGA	Thyroid Carcinoma	0.0400	0.0240	6.9e-03	0.006	0.015	-0.003	NA	0.007	7.4e-02	1.2e-02	9.4e-01	NA	5.6e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Medication: Ventolin 100micrograms inhaler	4.8	6.2	12.8	2.6	3.3	0.2	2.6	3.0	1.4	1.3	3.1	1.6	3.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.6	9.6	31.9	-3.1	-2.8	-1.3	-4.0	-2.0	-0.2	-5.7	-1.8	-4.6	-0.6
Blood White Count	3.7	27.3	50.6	6.6	6.5	0.4	5.3	5.7	3.3	3.7	7.1	3.8	6.0
Current tobacco smoking	3.5	5.7	9.2	-2.5	-3.0	-2.0	-2.5	-1.9	-1.4	-1.9	-2.5	-2.9	-2.7
Depression (self-reported)	3.5	4.2	8.2	-2.1	-2.8	0.8	-1.9	-0.9	-0.6	-2.4	-2.4	-2.9	-2.1
Smoking status: Current	3.2	5.1	8.2	-2.5	-2.8	-1.8	-2.5	-1.8	-1.4	-1.7	-2.2	-2.9	-2.5
Noisy workplace	2.9	3.6	17.0	1.0	2.1	0.1	0.7	4.1	1.0	0.4	2.5	-0.3	2.4
Deep venous thrombosis (DVT) (self-reported)	2.9	3.8	7.9	-2.1	-2.2	-1.4	-1.9	-2.0	-1.5	-2.8	-1.9	-2.2	-1.0
Eye problems/disorders: Diabetes related eye disease	2.8	3.1	8.2	-1.2	-2.4	-0.3	-0.6	-1.8	-2.4	1.0	-2.2	-0.4	-2.9
Sensitivity / hurt feelings	2.7	4.6	7.2	-2.3	-2.7	-0.9	-2.0	-2.2	-1.4	-1.7	-2.6	-2.1	-2.7
Frequency of unenthusiasm / disinterest in last 2 weeks	2.6	3.5	12.2	-1.8	-2.1	-0.8	-1.4	-0.4	-1.8	-2.0	-1.6	-3.5	-1.7
Ever depressed for a whole week	2.6	3.3	5.6	-1.6	-2.1	-1.0	-2.4	-1.2	-2.1	-0.5	-1.7	-2.2	-2.2
Prostate Cancer	2.5	3.5	7.8	2.5	2.4	0.9	2.7	0.8	1.2	1.5	1.4	2.8	0.9
Lung FVC	2.5	12.9	53.1	-0.9	0.6	-1.5	-3.6	1.7	2.8	-7.3	1.7	-5.0	4.5
Ever had hysterectomy (womb removed)	2.5	2.8	5.3	-1.9	-1.9	-1.4	-1.9	-1.2	0.2	-1.8	-2.3	-1.4	-1.8
Forced expiratory volume in 1-second (FEV1), Best measure	2.5	8.1	29.9	-3.0	-1.7	-0.3	-3.8	-2.1	-0.0	-5.5	-0.8	-4.4	0.7
Qualifications: nursing, teaching	2.5	3.8	7.3	-2.4	-2.1	0.9	-2.7	-2.2	-2.2	-0.7	-2.0	-1.8	-1.7
Ever smoked	2.5	4.3	8.9	-2.8	-2.3	-0.8	-2.5	-0.8	-1.3	-1.2	-2.4	-3.0	-2.3
Ovarian Cancer	2.4	3.1	5.5	-2.0	-2.0	-1.0	-2.4	-1.1	-0.9	-1.3	-2.2	-1.9	-2.1
Smoking Status	2.4	5.7	11.8	-3.1	-2.6	-1.3	-3.0	-1.0	-0.4	-2.6	-2.5	-3.4	-2.1
Past tobacco smoking	2.4	4.4	11.9	2.9	2.0	0.2	2.8	-0.4	0.6	1.9	2.1	3.4	1.7
Medication: Ibuprofen	2.4	2.9	9.3	-1.6	-1.2	-2.1	-2.1	0.7	-0.5	-3.0	-0.8	-2.3	0.3
Qualifications: CSEs or equivalent	2.3	3.1	6.8	-2.1	-1.6	-1.6	-2.6	-0.8	-1.3	-2.2	-1.5	-2.1	-0.7
Chronic bronchitis/emphysema (father)	2.3	2.7	5.4	1.7	1.6	1.6	2.1	1.6	1.1	2.0	1.3	2.3	0.5
Major Depression (MDD)	2.2	2.7	4.2	1.9	1.8	2.0	1.9	0.2	1.1	0.9	1.9	1.8	2.0
Forced vital capacity (FVC)	2.2	8.6	34.4	-2.8	-1.3	-0.4	-4.0	-1.1	0.9	-5.9	-0.5	-4.5	1.8
Ever unenthusiastic/disinterested for a whole week	2.2	2.7	6.0	-1.8	-1.9	-1.4	-2.5	-0.5	-2.1	0.1	-0.9	-2.3	-1.4
Forced expiratory volume in 1-second (FEV1)	2.2	7.5	27.1	-2.7	-1.7	-0.5	-3.8	-2.5	0.2	-5.2	-1.0	-3.8	0.8
Mouth/teeth dental problems: Bleeding gums	2.2	2.8	6.5	-1.9	-1.6	0.2	-1.4	-1.1	-0.0	-2.3	-2.0	-2.6	-1.7
Mean Putamen Volume	2.1	2.4	4.0	-1.8	-1.9	-2.0	-2.0	-1.4	-1.7	-1.2	-1.4	-0.9	-0.4
Number of live births	2.1	2.9	6.8	-1.7	-1.6	-2.2	-1.8	-1.0	-0.7	-2.6	-1.2	-2.3	-0.7
Medication: Ibuprofen (e.g. Nurofen)	2.1	2.6	8.4	-1.5	-1.4	-1.9	-2.0	0.2	-0.4	-2.9	-1.1	-2.2	-0.2
Illnesses of father: None of the above (group 1)	2.1	2.6	5.5	-2.3	-1.9	-0.4	-1.6	0.4	-1.5	0.5	-1.9	-1.6	-2.2
Serious illness, injury or assault to yourself	2.0	2.4	4.9	-1.7	-1.9	-1.6	-2.2	-0.4	-0.5	-1.3	-1.6	-1.7	-1.6
Blood clot in the leg (DVT)	2.0	2.6	6.3	-1.7	-1.8	-1.0	-1.6	-1.3	-1.2	-2.5	-1.6	-1.8	-0.7
Forced vital capacity (FVC), Best measure	2.0	7.4	32.2	-2.4	-0.7	0.1	-3.2	-0.7	0.8	-5.7	0.3	-4.4	2.2
Ever used hormone-replacement therapy (HRT)	1.9	2.4	5.8	-1.9	-1.7	-0.6	-1.6	-0.2	-1.1	-0.4	-1.6	-2.4	-2.2
Peak expiratory flow (PEF)	1.9	4.4	15.4	-2.0	-1.7	0.2	-2.4	-3.9	-0.9	-3.0	-1.6	-1.7	-0.6
Medication for cholesterol, blood pressure or diabetes	1.9	3.2	6.6	-1.9	-1.3	-1.4	-2.3	-2.6	-1.5	-2.3	-0.7	-2.1	-0.0
HbA1C	1.8	1.9	5.4	-1.0	-1.5	-1.3	-1.2	-2.3	-0.2	-1.4	-1.6	-0.9	-1.5
Stomach or abdominal pain in last month	1.8	2.3	4.2	-1.6	-1.9	-1.3	-1.5	-0.5	-0.5	-1.4	-1.7	-2.0	-1.9
Smoking status: Previous	1.8	2.6	7.1	-2.3	-1.3	0.2	-2.0	0.9	-0.4	-1.4	-1.8	-2.7	-1.4
Neuroticism (2016)	1.7	2.5	6.0	-1.9	-1.4	0.1	-2.4	-0.7	-0.6	-1.5	-1.5	-2.5	-1.4
Birth weight of first child	1.7	3.1	8.7	1.9	1.5	1.3	2.3	0.2	1.2	2.4	1.4	2.9	0.2
Medication: Bendroflumethiazide	1.7	2.6	5.3	2.3	1.9	0.0	1.9	0.4	1.9	0.5	1.6	1.9	1.9
Risk taking	1.7	2.4	6.4	-1.7	-2.2	0.6	-0.7	-1.6	-0.0	-1.0	-2.5	-0.6	-2.4
Waist Hip Ratio (WHR)	1.6	7.1	21.3	2.1	2.8	3.0	1.5	1.9	2.6	0.3	3.6	1.6	4.6
Severe depression (siblings)	1.6	1.8	3.8	-1.5	-1.7	1.1	-1.8	-0.6	-0.5	-0.2	-1.9	-0.6	-1.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.6	2.1	3.7	-1.6	-1.9	-0.4	-1.7	-0.4	-0.7	-1.3	-1.5	-1.9	-1.9
Mood swings	1.6	3.0	10.6	-1.3	-1.7	-0.3	-2.1	-0.5	-0.8	-3.3	-1.5	-2.5	-0.6
Depression (Nagel 2018)	1.5	2.3	8.3	-1.2	-1.6	-1.3	-1.3	-0.3	-0.5	-2.3	-1.1	-2.9	-0.5
Neuroticism (Nagel 2018)	1.5	3.6	9.2	-1.8	-1.8	-1.6	-2.8	-0.2	-0.0	-3.0	-1.6	-2.7	-0.4
Frequency of depressed mood in last 2 weeks	1.5	2.2	8.4	-1.1	-1.7	-1.1	-1.2	-0.0	-0.6	-1.9	-1.2	-2.9	-1.0
Diabetes (mother)	1.5	2.0	6.4	-1.0	-1.2	-2.5	-1.8	0.2	-1.2	-0.3	-1.4	-0.9	-1.7
Fed-up feelings	1.5	2.7	8.6	-1.1	-1.5	-0.3	-2.1	0.0	-0.9	-2.9	-1.0	-2.9	0.2
Medication: Atenolol	1.5	1.8	5.1	2.3	1.3	0.5	1.6	1.3	0.8	1.1	1.2	1.8	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.7	4.0	-1.7	-1.2	-2.0	-1.3	-1.0	-0.9	-0.9	-1.0	-1.8	-0.7
High cholesterol (Self-reported)	1.5	2.6	7.5	2.1	1.0	0.9	2.7	0.9	1.9	1.7	0.6	2.1	-0.3
Age at First Birth	1.4	2.1	5.6	1.3	1.1	2.4	1.7	0.7	-0.5	2.0	1.2	1.6	0.5
HDL Cholesterol	1.4	2.4	3.9	1.6	2.0	1.6	1.8	0.9	0.2	1.5	1.9	1.4	1.6
Illnesses of mother	1.4	1.7	9.7	-0.0	0.3	3.1	0.9	-0.8	-1.0	2.0	0.6	0.5	0.1
Medication: Seretide 50 evohaler	1.4	1.6	5.3	0.3	0.4	1.8	0.7	2.3	-1.1	2.1	0.1	0.3	-0.7
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	2.5	1.4	0.9	-1.6	1.1	0.8	1.5	-0.3	1.2	1.0	1.3
Medication: Lansoprazole	1.3	1.5	4.1	0.6	1.3	0.3	0.7	1.0	1.8	0.9	2.0	0.6	1.7
Loud music exposure frequency	1.3	1.4	5.7	-1.1	-1.2	0.4	-1.4	0.4	-1.0	0.6	-1.1	-0.9	-2.4
Comparative body size at age 10	1.3	3.7	10.3	-1.5	-2.7	-1.4	-0.8	-1.1	-1.9	-0.1	-3.1	0.4	-3.2
Suffer from ‘nerves’	1.3	2.0	4.8	-1.2	-1.3	-1.1	-2.0	-1.3	-0.8	-1.9	-0.9	-2.2	-0.6
Ever had prostate specific antigen (PSA) test	1.3	1.5	2.4	1.4	1.3	1.4	0.5	1.4	1.2	0.5	1.4	0.9	1.6
Vascular/heart problems diagnosed by doctor	1.3	3.4	11.2	-2.5	-1.5	-0.2	-2.3	-1.7	-3.4	-0.0	-1.2	-2.0	-1.1
Depressed Affect (Nagel 2018)	1.2	2.5	8.9	-0.9	-1.0	-1.0	-2.4	0.7	0.7	-3.0	-0.6	-2.3	0.9
Number of treatments/medications taken	1.2	2.2	6.2	1.5	1.4	-1.1	1.8	2.5	1.1	0.3	1.7	0.2	1.8
Had menopause	1.2	1.5	3.3	1.5	1.4	-0.6	0.7	0.2	1.5	0.5	1.4	1.8	1.6
Pain all over the body in last month	1.2	1.2	3.0	1.1	1.2	-1.5	0.5	1.1	-1.1	1.1	1.7	0.3	0.9
Diabetes (self-reported)	1.2	1.9	5.0	0.1	-0.9	-0.5	1.2	-0.9	-2.0	2.1	-1.1	1.0	-2.2
Neuroticism score	1.2	2.6	6.1	-1.4	-1.6	-0.3	-2.0	-1.0	-0.9	-2.4	-1.6	-2.5	-0.9
Medication: Cholesterol lowering	1.2	1.9	4.7	1.4	0.6	1.4	2.1	1.3	0.5	2.2	0.1	1.7	-0.7
Gout (self-reported)	1.2	1.6	3.8	1.3	1.1	-0.1	1.7	0.6	1.6	1.4	1.1	2.0	0.7
Medication: Omeprazole	1.2	1.4	2.8	-1.4	-1.1	0.2	-1.5	0.4	-1.6	0.9	-0.8	-1.4	-1.7
Illnesses of father: Heart disease	1.2	1.7	4.2	1.8	1.2	0.3	1.2	0.2	2.1	-0.2	1.1	1.8	1.5
Friendships satisfaction	1.2	1.5	2.6	-1.2	-1.6	-1.6	-1.4	-0.5	-1.4	0.2	-1.3	-0.7	-1.4
Systolic Blood Pressure	1.1	5.6	20.7	2.8	2.4	-0.2	2.1	0.8	4.5	-1.3	1.4	2.5	2.6
Lung FEV1/FVC ratio	1.1	5.5	16.6	-1.5	-2.6	-1.2	-1.3	-4.1	-1.9	-0.9	-2.9	-0.7	-3.6
Medication: Metformin	1.1	1.6	4.7	0.7	-0.3	0.1	2.2	-1.3	-1.0	2.1	-0.2	1.3	-1.5
High blood pressure	1.1	3.0	13.0	2.1	1.3	0.6	2.3	0.7	3.6	-0.1	0.7	1.9	0.5
Medication: Ramipril	1.1	1.4	3.2	1.7	1.0	0.6	1.4	0.5	0.1	1.1	1.3	1.8	1.1
Worrier / anxious feelings	1.1	2.2	3.7	-1.1	-1.4	-1.4	-1.9	-0.8	-1.4	-1.9	-1.6	-1.7	-1.0
Number of full brothers	1.1	1.4	3.4	0.8	1.2	1.3	0.3	1.2	0.1	-1.8	1.2	-1.0	1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	3.2	-0.8	-1.4	0.8	-1.0	-1.3	-0.0	-1.8	-1.7	-0.5	-0.9
Hypertension (Self-reported)	1.1	3.0	12.1	2.2	1.3	0.2	2.6	0.5	3.5	0.1	0.7	2.0	0.4
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	4.0	-1.4	-1.0	0.4	-1.4	-0.2	-1.2	-0.0	-0.7	-2.0	-1.4
Supplements: Calcium	1.1	1.3	5.0	1.2	1.3	0.1	0.6	0.4	-0.2	2.2	1.6	0.9	0.7
Worry (Nagel 2018)	1.0	2.1	6.7	-1.2	-1.3	-0.9	-2.1	-0.8	-0.5	-2.6	-1.2	-1.9	-0.2
Neuroticism	1.0	2.4	7.9	-1.3	-1.3	-0.4	-2.1	-0.3	0.4	-2.8	-1.1	-2.5	0.0
Impedance of leg (right)	1.0	4.7	17.5	0.9	2.7	0.6	-0.1	2.6	1.2	0.2	3.5	-0.8	4.2
Townsend deprivation index at recruitment	1.0	1.4	2.9	-1.5	-1.7	-0.7	-1.4	-0.4	-1.2	-0.5	-0.8	-1.6	-1.1
Qualifications: None of the above	1.0	2.2	4.8	1.5	1.5	-1.4	1.0	1.8	1.8	-0.3	1.8	0.5	2.2
Illnesses of siblings	1.0	1.4	3.1	-1.6	-1.5	0.0	-0.9	-0.1	-1.7	0.3	-1.3	-1.1	-1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	6.5	-1.2	-1.1	0.1	-1.5	0.2	-0.7	-1.4	-0.8	-2.5	-0.6
Headache pain in last month	1.0	1.7	3.3	-1.1	-1.6	-1.6	-0.7	-0.4	0.2	-1.8	-1.6	-1.5	-1.4
Emphysema/chronic bronchitis	1.0	1.2	4.7	0.7	1.0	-0.2	1.1	2.2	0.1	1.0	1.1	0.9	1.2
Eye problems/disorders: Glaucoma	1.0	1.2	3.5	1.4	1.0	0.2	1.3	0.5	1.9	0.8	1.1	0.7	0.8
Unable to work because of sickness or disability	1.0	1.4	5.4	-1.1	-1.1	-0.5	-1.4	-0.0	-1.5	-1.0	-0.3	-2.3	-0.3
Body Mass Index (BMI) (2010)	0.9	1.3	6.0	0.3	-0.1	-1.0	0.7	-1.1	-0.0	1.4	-0.9	2.5	-1.0
Crohns Disease (2012)	0.9	1.4	3.8	1.7	1.3	0.0	1.1	0.0	0.3	1.7	1.1	1.9	0.2
BMI	0.9	5.2	14.6	-0.6	-2.6	-1.7	0.6	-3.0	-1.0	-0.5	-3.6	1.6	-3.8
Body mass index (BMI)	0.9	3.8	10.6	-0.6	-2.7	-1.7	0.3	-2.0	-1.2	-0.3	-3.2	1.2	-3.2
Impedance of leg (left)	0.9	4.4	16.2	1.1	2.8	0.6	0.0	2.4	0.8	0.4	3.5	-0.6	4.0
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	7.5	0.6	0.8	2.7	1.0	-0.2	0.9	0.6	1.1	0.2	0.8
Medication: Simvastatin	0.9	1.3	4.7	0.9	0.8	0.4	1.3	2.2	0.7	1.5	0.5	1.3	-0.2
Falls in the last year	0.9	1.2	3.3	1.4	1.1	0.1	0.9	0.4	1.1	0.1	1.5	1.1	1.8
Medication: Paracetamol	0.9	1.5	5.6	1.0	1.1	-0.8	-0.1	0.9	0.7	-2.4	1.0	-0.4	2.1
Medication: Blood pressure	0.9	1.6	4.5	1.5	0.8	-0.1	2.1	1.6	1.6	0.5	0.4	1.6	0.4
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	4.1	0.3	0.9	2.0	1.0	-0.8	-0.8	0.4	0.7	0.8	1.5
Osteoarthritis (self-reported)	0.9	1.2	2.3	-1.4	-1.5	-1.3	-0.9	-1.0	-1.1	-0.5	-1.0	-1.1	-0.9
Medication: Paracetamol	0.9	1.4	5.1	0.5	0.7	-1.2	-0.7	1.5	0.2	-2.3	0.7	-1.1	1.4
Medication: Lisinopril	0.9	1.2	2.1	1.2	0.8	-1.2	1.4	1.3	1.5	0.2	0.7	1.2	0.6
Medication: Atorvastatin	0.9	1.1	4.3	1.5	0.3	-0.3	2.1	-0.5	1.2	0.3	-0.4	1.5	-0.8
Average weekly beer plus cider intake	0.9	1.4	4.6	0.5	1.1	0.1	0.2	1.4	1.2	-2.1	0.7	-0.3	1.9
Heart attack/myocardial infarction (self-reported)	0.9	1.2	5.7	1.1	0.7	0.7	0.4	2.4	-0.4	1.0	1.0	1.0	0.9
Impedance of whole body	0.9	4.7	13.5	0.8	2.6	2.5	0.2	2.7	0.7	0.9	3.3	-0.7	3.7
LDL Cholesterol	0.8	1.2	4.6	-0.9	-0.8	-0.7	-1.4	-0.4	0.0	-2.1	-0.4	-1.8	0.2
Triglycerides	0.8	1.3	3.4	-0.8	-1.6	-0.2	-0.9	-0.9	-0.1	-1.1	-1.5	-1.2	-1.8
Type 2 Diabetes (T2D) (2012)	0.8	0.9	2.3	0.5	1.1	-0.1	1.5	-0.4	1.5	0.8	0.8	1.0	0.6
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	4.6	-0.7	-0.3	-0.4	-2.1	1.0	-1.4	-0.4	-0.2	-1.2	0.1
High blood pressure (mother)	0.8	1.1	5.0	0.7	0.4	-2.2	-0.3	1.3	1.6	-1.0	-0.2	0.6	0.1
Nervous feelings	0.8	1.5	4.1	-1.1	-1.1	-0.7	-2.0	-0.9	-1.3	-1.1	-1.2	-1.3	-1.1
Time employed in main current job	0.8	0.9	2.2	-0.4	-0.8	-0.1	-1.5	-1.1	-1.2	0.2	-1.1	0.0	-1.4
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	2.6	-0.3	-0.8	-1.6	-1.0	-0.3	1.0	-0.5	-0.9	-0.5	-1.5
Lung cancer (father)	0.8	1.0	3.4	0.4	0.4	1.0	0.5	1.8	0.9	-0.4	0.7	0.4	1.9
Pulse wave Arterial Stiffness index	0.8	0.9	2.3	1.0	1.1	-0.4	0.4	-0.1	1.5	-0.2	1.0	1.0	1.5
Length of working week for main job	0.8	0.8	3.3	1.1	0.5	-0.7	1.1	-0.5	-0.3	1.0	-0.0	1.8	-0.7
Age at first live birth	0.8	1.5	6.0	1.0	1.3	2.4	1.5	0.5	0.3	1.4	0.8	1.0	0.5
Pulse wave peak to peak time	0.8	0.9	2.7	-1.1	-1.0	0.4	-0.6	0.1	-1.6	0.2	-0.8	-1.0	-1.3
Chest pain or discomfort	0.8	1.2	3.0	-0.7	-1.0	1.4	-0.5	-0.5	-1.1	-1.7	-1.1	-1.3	-0.9
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	3.3	-0.9	-0.8	-0.4	-1.8	0.8	0.5	-1.0	-0.8	-1.2	-0.6
Diabetes diagnosed by doctor	0.8	1.3	4.0	0.4	-0.5	-0.5	1.5	-0.4	-1.2	2.0	-0.6	1.0	-1.8
Miserableness	0.8	1.5	4.7	-0.9	-0.8	-0.5	-1.7	-0.7	0.3	-2.2	-0.9	-2.0	-0.0
Mother’s age at death	0.8	1.0	2.9	-0.9	-0.9	-0.5	-1.4	-1.0	-0.7	-1.7	-0.7	-1.2	-0.3
Medication: Blood pressure	0.8	1.5	3.9	2.0	1.0	-1.3	1.5	0.2	1.6	-0.4	0.9	1.3	0.9
Alzheimer’s Disease (in mother)	0.7	0.8	2.9	-0.4	-0.9	0.3	-1.7	-1.3	-0.9	-0.2	-0.9	-0.2	-0.8
Alzheimer’s Disease (in father)	0.7	0.7	3.1	0.7	0.5	-1.8	1.0	1.0	0.3	0.8	0.9	-0.1	0.2
Cardiovascular Disease	0.7	2.4	13.5	1.7	0.9	-0.3	2.1	0.4	3.7	-0.1	0.2	1.5	0.0
Type 2 Diabetes (T2D) (2018)	0.7	1.2	2.8	-0.1	-0.8	-1.0	1.0	-1.3	-1.5	1.3	-0.8	0.5	-1.7
Hearing difficulty/problems: Yes	0.7	1.1	2.3	1.5	1.5	-0.1	0.7	0.9	-0.1	0.4	1.4	0.7	1.4
Systolic blood pressure, automated reading	0.7	1.9	9.6	1.1	0.3	-0.3	0.5	-1.4	3.1	-1.9	-0.3	1.5	0.7
Medication for hormone replacement therapy	0.7	0.8	2.1	-1.2	-0.7	-0.5	-1.1	0.9	-0.5	0.1	-0.7	-1.5	-0.8
Age when periods started (menarche)	0.7	1.7	4.1	1.4	1.8	1.1	0.7	1.3	0.3	-0.7	2.0	-0.9	1.9
Mouth/teeth dental problems	0.7	1.0	2.7	1.3	1.0	0.0	0.7	0.4	-0.8	1.1	1.2	1.6	1.0
Impedance of arm (right)	0.7	3.2	8.8	0.3	1.6	3.0	0.3	2.4	0.3	0.6	2.5	-1.1	2.7
Hip circumference	0.7	3.0	7.1	-0.9	-2.3	-1.7	-0.3	-1.7	-1.8	0.2	-2.6	1.0	-2.7
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	4.9	-1.1	-1.2	-1.0	-0.4	-0.9	-0.9	-0.7	-0.6	-2.2	-0.9
Impedance of arm (left)	0.7	3.4	12.5	0.2	1.7	3.5	0.2	2.1	0.3	0.7	2.4	-1.0	2.6
Worry too long after embarrassment	0.7	1.2	5.8	-0.6	-0.9	1.3	0.1	-2.4	-0.7	-0.2	-0.9	-0.3	-1.2
Medication for pain relief, constipation, heartburn	0.7	1.2	5.9	0.5	0.3	1.2	0.2	-0.6	-0.3	2.4	0.3	1.8	-0.4
Heart disease (mother)	0.7	0.9	4.3	0.6	0.6	-2.1	0.3	0.9	0.7	-1.1	0.6	-0.2	0.9
Knee pain experienced in last month	0.7	1.0	2.8	-1.3	-1.6	1.0	-0.8	-0.3	-0.3	-0.6	-0.9	-1.7	-0.5
Age started oral contraceptive pill	0.7	0.9	2.5	0.7	0.9	0.6	0.9	-1.6	1.4	0.1	0.9	0.6	0.8
Schizophrenia (2018)	0.6	1.2	3.1	-0.8	-1.3	1.1	-0.9	-1.8	-0.7	-0.2	-1.6	-0.2	-1.1
Schizophrenia vs Biploar Disorder	0.6	0.8	2.6	-0.7	-1.1	0.0	-0.9	-0.4	-1.1	-0.0	-1.6	0.2	-1.4
Blood Red Count	0.6	5.5	9.6	3.1	2.5	2.1	2.3	2.4	2.3	1.9	2.2	2.9	1.4
Hair/balding pattern: Pattern 2	0.6	0.8	2.7	0.3	0.4	1.6	0.5	1.4	1.4	0.4	0.4	0.4	0.2
Heart attack	0.6	0.8	5.3	0.9	0.3	0.4	0.1	2.3	-0.5	0.8	0.6	0.6	0.5
Arm fat percentage (right)	0.6	2.5	8.1	-0.6	-2.4	-0.7	0.4	-0.9	-1.3	0.2	-2.6	0.9	-2.8
Arm fat mass (right)	0.6	2.5	6.6	-0.2	-2.0	-0.9	0.8	-1.6	-1.1	0.3	-2.4	1.6	-2.6
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	4.6	0.8	-0.0	1.3	1.0	-0.5	2.1	-0.8	-0.7	1.4	0.5
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.8	0.1	0.5	-1.1	-0.1	0.5	0.4	-1.7	0.4	-0.6	1.5
High blood pressure (siblings)	0.6	0.9	4.6	0.7	1.0	-0.8	0.6	0.3	2.1	-0.2	1.0	-0.0	0.9
Number of children fathered	0.6	0.6	2.6	-0.6	-0.7	-1.6	-0.5	-0.6	-0.2	-0.4	-0.4	-1.2	-0.7
Qualifications: College or University degree	0.6	1.7	6.2	0.5	0.0	1.5	1.3	-0.8	-0.8	2.5	-0.1	2.2	-0.8
Mouth/teeth dental problems: Loose teeth	0.6	0.8	1.6	-1.0	-1.1	0.1	-0.3	0.3	0.0	-0.9	-1.1	-1.3	-1.3
Migraine (self-reported)	0.6	0.7	2.1	0.9	0.8	-0.8	0.1	1.5	0.1	-0.5	0.7	0.1	1.4
Leg pain on walking	0.6	0.8	1.7	-1.0	-1.0	-0.3	0.1	-1.1	-1.2	0.2	-0.6	-1.3	-1.0
Supplements: Vitamin C	0.6	0.7	2.4	0.7	0.8	0.2	0.3	1.1	0.8	-0.1	1.4	0.0	1.5
Arm fat percentage (left)	0.6	2.5	7.7	-0.6	-2.4	-0.5	0.5	-1.0	-1.1	0.2	-2.7	1.1	-2.8
Average weekly red wine intake	0.6	0.9	3.1	1.0	1.1	0.2	0.9	-0.5	0.2	1.7	0.5	1.8	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.8	1.0	0.8	0.7	-0.2	1.4	-0.6	1.3	0.9	0.2	0.3
Arm fat mass (left)	0.6	2.6	7.0	-0.3	-2.2	-0.6	0.6	-1.7	-1.1	0.1	-2.6	1.7	-2.6
Number of self-reported non-cancer illnesses	0.6	1.1	4.3	1.1	0.3	0.0	1.1	0.5	2.1	-1.4	0.5	-0.2	1.4
Ever taken oral contraceptive pill	0.6	0.6	2.7	-0.6	0.0	1.6	-0.1	-1.0	-0.4	-0.2	0.5	-1.2	0.6
Supplements: Fish oil (including cod liver oil)	0.6	0.8	3.6	0.0	0.5	-1.2	-0.9	0.7	-0.1	-1.0	0.9	0.1	1.9
Illnesses of father: High blood pressure	0.6	0.8	2.4	1.6	1.1	0.3	0.7	-0.4	0.5	-1.2	0.7	0.5	0.9
Heart disease (siblings)	0.6	0.7	1.8	1.3	0.8	0.6	0.6	0.9	0.6	0.5	0.6	1.2	0.5
Intelligence (Savage-Jansen 2018)	0.5	1.5	4.5	-0.9	-1.1	-0.5	-1.0	-1.5	-2.1	0.3	-1.5	0.0	-1.5
Alzheimer’s Disease (including proxy)	0.5	0.7	1.9	-0.1	-0.8	-0.5	-1.4	-0.7	-1.3	-0.1	-0.7	-0.5	-0.9
Ulcerative Colitis (UC)	0.5	0.9	3.1	-0.4	0.1	-1.8	0.1	0.8	0.6	-1.0	0.6	-1.6	0.9
Breast Cancer	0.5	1.2	7.0	0.8	0.8	2.7	-0.2	-0.7	-0.0	0.5	0.9	1.3	0.8
Coronary Artery Disease (CAD)	0.5	0.6	1.6	0.6	0.9	-0.0	0.0	1.3	0.0	0.4	1.3	0.5	1.3
Fasting Glucose	0.5	0.6	1.0	0.6	0.9	0.7	0.7	0.6	0.8	1.0	0.6	0.9	0.5
Hypothyroidism (self reported)	0.5	1.2	5.9	0.9	0.3	0.9	0.5	0.1	2.4	-1.0	-0.2	1.4	1.0
Vitamin and mineral supplements	0.5	0.7	2.2	-0.6	-0.7	-1.4	-0.5	-0.4	-0.0	-0.7	-1.5	0.0	-0.9
Medication: Levothyroxine sodium	0.5	0.8	2.1	-0.5	-1.1	-0.1	-0.1	-1.2	1.1	-1.4	-1.5	-0.2	-0.2
Alcohol usually taken with meals	0.5	0.8	2.6	1.1	0.7	0.3	0.4	-1.0	0.1	1.5	0.4	1.6	-0.2
Alcohol intake versus 10 years previously	0.5	0.8	6.2	0.2	0.4	0.2	-0.1	2.5	0.8	-0.1	0.4	-0.0	0.9
Breastfed as a baby	0.5	0.6	1.3	0.6	0.8	0.7	0.8	0.9	1.1	-0.0	0.8	0.6	0.7
Pulse wave reflection index	0.5	0.6	4.0	0.5	0.1	-2.0	0.2	-0.6	-0.2	-0.9	-0.6	0.5	-0.4
Medication: Amlodipine	0.5	0.7	4.8	-0.3	-0.1	-0.9	0.2	-0.4	2.2	-0.9	-0.7	0.3	-0.3
Shortness of breath walking on level ground	0.5	0.6	1.4	0.3	0.7	0.9	1.2	0.6	0.9	0.4	0.9	0.2	1.2
Eye problems/disorders: None of the above	0.5	0.5	2.0	0.2	0.8	1.4	-0.3	0.1	0.4	1.0	0.6	1.0	0.2
Neck or shoulder pain in last month	0.5	0.8	4.3	-0.3	-0.1	-2.1	-0.7	0.6	0.0	-1.2	-0.3	-0.8	0.4
Alcohol intake frequency.	0.5	1.3	6.2	1.0	0.3	0.1	0.7	2.5	-0.6	1.4	0.8	1.3	0.6
Eye problems/disorders: Cataract	0.5	0.6	2.6	0.1	-0.8	-0.7	0.2	0.2	-1.6	-0.8	-0.6	-0.9	-0.6
Mineral and other dietary supplements	0.5	0.7	2.5	-0.3	-0.8	0.7	0.7	-0.8	0.8	0.4	-1.1	-0.3	-1.6
Breast cancer (self-reported)	0.5	0.6	1.4	0.9	0.3	0.8	0.3	0.1	1.1	-0.3	0.7	1.2	1.0
Wears glasses or contact lenses	0.5	0.6	3.1	0.5	0.5	-1.8	0.4	0.3	0.8	0.7	0.4	0.7	0.4
Financial situation satisfaction	0.5	0.6	1.8	0.1	0.6	-1.4	-0.2	1.2	0.8	-0.9	0.5	-0.3	0.8
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.8	0.0	0.5	1.1	1.0	0.4	1.7	-0.1	0.2	-0.3	-0.0
Commuting to job workplace: Public transport	0.5	0.6	1.8	0.3	0.7	-0.2	0.3	-0.1	1.2	1.3	0.7	1.0	0.3
Myopia	0.5	0.7	4.1	-0.4	0.2	2.0	-0.2	-1.0	-1.0	-0.0	-0.1	-0.7	0.1
Cholesterol lowering medication	0.5	0.8	2.0	0.9	0.3	-1.4	1.4	0.5	0.9	0.3	-0.1	1.2	-0.4
Pain experienced in last month	0.5	0.9	3.2	0.8	1.2	1.4	-0.0	-0.7	-0.3	0.9	0.5	1.8	0.3
Alcohol drinker status: Previous	0.5	0.5	1.3	0.4	0.6	-0.3	-0.8	1.1	-0.7	-0.2	1.0	0.2	1.0
Leg fat mass (left)	0.5	1.8	3.8	0.2	-1.3	-1.7	0.7	-1.3	-1.0	0.2	-1.8	2.0	-1.7
Bipolar Disorder or Schizophrenia	0.4	1.0	2.7	-0.9	-1.1	1.1	-1.0	-1.7	-0.4	-0.7	-1.2	-0.7	-0.9
Schizophrenia (2014)	0.4	0.9	2.5	-0.7	-0.8	1.6	-0.9	-0.9	-0.8	0.6	-1.2	0.1	-1.1
Ulcerative Colitis	0.4	0.6	4.0	-0.7	-0.5	-2.0	0.2	-0.4	0.2	-0.5	0.0	-1.0	-0.2
Height	0.4	6.8	24.2	2.2	3.0	0.9	1.9	-0.8	-1.3	1.6	3.8	2.6	4.9
Respiratory disease	0.4	1.0	2.8	0.3	1.1	0.5	1.0	1.0	0.4	-0.5	1.2	-1.2	1.7
Relative age of first facial hair	0.4	0.9	3.3	-1.2	-1.0	-0.5	-1.0	-0.5	-0.5	-0.6	-0.9	-1.8	-0.8
Supplements: Zinc	0.4	0.4	1.0	-0.0	0.3	0.4	-0.9	-0.7	-0.8	1.0	0.6	-0.5	0.5
Medication: Co-codamol	0.4	0.5	1.1	0.6	0.2	-1.1	0.8	0.2	-1.0	1.1	0.6	0.6	0.3
Leg fat-free mass (left)	0.4	1.9	5.5	-0.3	-1.4	-0.6	0.1	-2.4	-1.3	0.0	-1.9	1.6	-1.9
Maternal smoking around birth	0.4	0.6	2.9	-0.1	0.3	1.7	0.8	1.6	-0.0	0.2	-0.4	0.3	0.3
Leg predicted mass (left)	0.4	2.0	5.9	-0.4	-1.4	-0.6	0.1	-2.4	-1.4	-0.1	-1.9	1.6	-1.9
Weight	0.4	2.0	4.9	-0.1	-1.5	-0.6	0.6	-2.2	-1.4	0.3	-1.9	1.8	-1.9
Father’s age at death	0.4	0.6	1.6	0.0	0.7	-0.7	-0.3	-1.0	0.6	-1.0	0.7	0.1	1.3
Asthma	0.4	0.8	2.3	0.4	1.2	0.4	0.7	1.2	0.6	-0.4	1.0	-0.8	1.5
Birth weight	0.4	0.8	3.9	0.1	0.7	-0.3	0.1	1.2	-0.7	2.0	1.2	0.4	0.5
Arm fat-free mass (right)	0.4	1.8	7.6	-0.1	-0.9	-1.4	-0.2	-2.8	-1.1	-0.3	-1.5	1.7	-1.1
Health satisfaction	0.4	0.5	1.1	-0.7	-1.0	-0.2	-0.7	0.6	-0.7	0.5	-0.2	-1.1	-0.6
Medication: Allopurinol	0.4	0.6	2.0	0.8	0.7	-0.4	1.4	0.2	0.8	0.3	0.7	0.9	0.4
Leg fat mass (right)	0.4	1.6	4.2	0.3	-1.2	-1.6	0.9	-1.1	-0.6	0.1	-1.7	2.0	-1.5
Arm predicted mass (right)	0.4	1.9	7.9	-0.3	-1.1	-1.4	-0.2	-2.8	-1.1	-0.5	-1.6	1.4	-1.4
Overall health rating	0.4	0.9	4.7	-0.5	-0.9	-1.3	-0.2	0.7	-0.4	-0.9	-0.2	-2.2	-0.2
Medication: Aspirin	0.4	0.6	1.9	1.1	0.3	-1.0	0.6	1.4	0.4	-0.2	0.3	0.8	0.6
Illnesses of siblings: Diabetes	0.4	0.5	1.8	-0.4	-0.5	0.4	-0.5	-0.4	-0.6	-1.4	-1.2	0.1	-0.2
Leg fat-free mass (right)	0.4	2.0	6.7	-0.2	-1.3	-0.4	0.1	-2.6	-1.5	0.1	-1.8	1.6	-1.9
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.6	0.1	0.1	0.1	0.6	-1.6	0.6	-0.4	-0.3	1.1	0.7
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	2.0	-0.6	-0.5	0.3	-0.6	-1.4	1.2	-1.3	-0.8	0.1	0.2
Back pain experienced in last month	0.4	0.6	1.6	-0.7	-0.7	-0.2	0.4	0.8	1.2	-1.2	-0.3	-1.1	0.3
Asthma (self-reported)	0.4	0.8	1.9	0.5	1.3	0.4	0.8	1.3	0.5	-0.2	1.0	-0.7	1.4
Leg predicted mass (right)	0.4	2.0	6.7	-0.3	-1.4	-0.5	0.1	-2.6	-1.6	0.0	-1.8	1.5	-1.9
Hearing aid user	0.4	0.4	1.2	0.1	0.5	-0.2	-0.1	0.2	0.8	-1.1	0.6	-1.0	0.5
Leg fat percentage (left)	0.4	1.3	3.2	0.1	-1.2	-1.8	0.6	-0.6	-0.8	0.3	-1.5	1.6	-1.5
Arm fat-free mass (left)	0.4	1.8	7.0	-0.3	-1.2	-1.4	-0.0	-2.6	-1.2	-0.4	-1.6	1.4	-1.3
Pack years of smoking	0.4	0.6	1.4	1.2	0.8	0.8	1.1	0.4	0.4	0.0	0.7	1.1	0.7
Arm predicted mass (left)	0.4	1.8	6.7	-0.2	-1.1	-1.4	-0.3	-2.6	-1.2	-0.3	-1.6	1.5	-1.4
Irritable Bowel Disease (IBD)	0.3	0.6	1.5	0.6	0.8	-1.0	0.4	0.5	0.4	-0.6	1.2	-0.9	0.9
Primary Biliary Cirrhosis	0.3	0.4	0.8	0.2	0.5	0.9	0.4	0.9	0.1	0.9	0.4	0.6	0.9
Rheumatoid Arthritis	0.3	0.4	1.1	-0.3	0.3	0.8	0.5	0.1	-0.4	0.1	0.9	-0.9	1.1
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.9	-0.7	-0.9	0.5	-0.2	-0.1	-1.4	0.1	-0.6	-0.4	-0.2
Trunk fat percentage	0.3	1.1	4.6	0.6	-0.5	0.4	1.5	0.1	-0.8	1.4	-0.8	2.1	-0.9
Relative age voice broke	0.3	0.5	2.5	-0.2	0.2	-0.2	-0.7	-0.1	-1.6	1.1	0.1	-0.8	-0.6
Supplements: Glucosamine	0.3	0.4	1.8	0.3	0.2	-1.0	0.1	-0.7	0.3	-1.3	0.1	0.0	0.4
Trunk fat mass	0.3	1.3	5.3	0.5	-0.7	-0.1	1.3	-0.7	-1.0	1.2	-1.1	2.3	-1.1
Number of incorrect matches in round	0.3	0.5	2.3	0.5	0.4	-0.8	-0.1	1.5	0.5	-0.5	0.9	-0.5	0.5
Financial difficulties in last 2 years	0.3	0.5	1.4	-0.3	-0.3	-0.8	-0.7	1.2	0.5	-1.0	-0.1	-0.8	-0.1
Allergy	0.3	0.6	1.9	-0.2	-0.8	-1.2	-0.5	-0.8	-0.6	0.2	-0.9	0.4	-1.4
Trunk fat-free mass	0.3	1.6	7.1	-0.4	-1.1	-1.4	-0.3	-2.7	-1.1	-0.5	-1.3	1.0	-1.1
Pulse rate	0.3	0.5	1.0	0.2	0.6	1.0	0.8	0.2	0.8	0.1	1.0	-0.5	0.7
Happiness	0.3	0.4	1.7	-0.3	-0.4	-0.3	-0.4	0.2	-1.3	0.9	-0.0	-0.7	-0.6
Mouth/teeth dental problems: Dentures	0.3	0.4	2.0	-0.3	-0.2	0.2	-0.2	0.7	-1.0	1.4	0.5	-0.7	-0.1
Trunk predicted mass	0.3	1.7	7.3	-0.4	-1.2	-1.3	-0.4	-2.7	-1.2	-0.6	-1.4	0.9	-1.2
Standing height	0.3	2.7	6.6	1.0	2.0	2.2	0.5	-0.8	-0.7	1.1	2.4	1.4	2.6
Tense / ‘highly strung’	0.3	0.5	1.8	-0.3	-0.4	0.1	-1.0	1.4	-0.1	-0.6	0.1	-1.4	0.0
Hair/balding pattern: Pattern 4	0.3	0.6	3.4	1.0	0.1	-0.8	0.2	-0.4	-0.5	0.8	-0.3	1.8	-0.4
Glaucoma (self-reported)	0.3	0.4	0.9	0.9	0.3	-0.3	0.9	-0.2	0.9	1.0	0.4	0.3	0.1
Body fat percentage	0.3	1.1	4.2	0.5	-0.8	-0.3	1.3	-0.2	-0.6	1.1	-1.1	2.0	-1.2
Leg fat percentage (right)	0.3	1.1	3.2	0.2	-1.1	-1.8	0.8	-0.3	-0.2	0.2	-1.4	1.5	-1.3
Wheeze or whistling in the chest in last year	0.3	0.5	1.3	-0.3	-0.4	1.1	0.5	0.9	0.8	-0.4	-0.9	-0.7	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.0	-0.1	0.3	-0.1	0.7	0.9	0.8	-0.4	0.4	-0.2	1.0
Angina (self-reported)	0.3	0.3	1.1	0.3	0.2	0.6	0.4	1.1	-1.0	-0.2	0.4	-0.5	0.4
Whole body fat mass	0.3	1.4	4.6	0.3	-1.1	-0.5	1.1	-0.9	-1.0	0.8	-1.5	2.1	-1.4
Pulse rate, automated reading	0.3	0.9	2.5	0.1	0.9	1.6	0.2	0.7	1.0	0.2	1.4	-1.0	1.1
Comparative height size at age 10	0.3	1.8	6.4	0.7	1.0	1.4	0.9	-1.3	-0.8	1.9	0.7	2.5	0.8
Age at last live birth	0.3	0.4	2.4	-0.2	-0.0	1.5	-0.1	-0.9	-0.4	-0.5	-0.2	-0.3	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	2.7	-0.7	0.5	-0.5	-0.9	-0.4	-1.6	-0.6	0.5	-0.5	0.7
Whole body fat-free mass	0.3	1.8	7.3	-0.2	-1.2	-1.2	-0.1	-2.7	-1.2	-0.3	-1.5	1.4	-1.4
Loneliness, isolation	0.3	0.4	1.2	-0.2	-0.7	0.6	-0.5	1.1	-1.1	-0.3	-0.4	-0.5	-0.0
Commuting to job workplace: Walk	0.3	0.3	0.9	-0.8	-0.1	0.3	-0.6	-0.8	0.6	-0.4	-0.2	-1.0	-0.1
Osteoporosis (self-reported)	0.3	0.3	1.6	-0.5	0.1	-0.7	0.3	1.3	-0.1	0.8	0.4	-0.4	-0.3
Medication: Aspirin	0.3	0.5	1.8	0.7	-0.1	-1.4	0.4	0.9	0.6	-0.7	-0.3	0.6	0.0
Whole body water mass	0.3	1.8	7.0	-0.3	-1.2	-1.1	-0.1	-2.6	-1.3	-0.4	-1.6	1.3	-1.4
Pain type(s) experienced in last month: Hip pain	0.3	0.4	2.7	0.1	0.3	-0.3	0.5	0.0	1.6	-0.6	0.7	-0.1	0.7
Alcohol drinker status: Never	0.3	0.4	1.0	0.9	-0.0	0.2	1.0	0.2	0.1	0.8	0.4	1.0	0.2
Basal metabolic rate	0.3	1.8	6.5	-0.2	-1.3	-1.1	0.1	-2.5	-1.3	-0.2	-1.6	1.5	-1.5
Number of operations (self-reported)	0.3	0.5	2.3	0.1	-0.2	-1.5	-0.4	0.1	-0.0	-1.1	0.1	-0.9	0.4
Fractured/broken bones in last 5 years	0.3	0.4	1.1	0.3	0.6	-1.1	-0.2	1.0	0.0	-0.0	0.9	0.3	0.9
Crohns Disease (2017)	0.2	0.5	1.8	1.3	1.0	-0.0	0.7	-0.0	-0.2	0.5	1.1	0.3	0.1
Reaction Time	0.2	0.4	1.5	-0.4	-0.2	0.6	-0.1	0.9	0.0	0.7	0.1	-1.2	-0.7
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.7	0.4	0.3	0.1	-0.1	-0.8	-1.3	0.9	0.0	1.3	0.1
Lupus	0.2	0.3	0.6	-0.4	-0.2	-0.6	-0.7	0.1	0.3	-0.8	0.1	-0.6	0.5
Allergy or Eczema	0.2	0.6	1.2	-0.0	0.3	0.7	-0.2	1.1	1.0	-0.9	0.7	-1.0	0.6
Chronotype (morning person)	0.2	0.5	1.8	0.0	0.2	-1.3	-0.4	1.1	0.3	0.9	0.5	0.6	0.7
Average weekly spirits intake	0.2	0.3	1.4	-0.5	0.0	-0.2	-0.2	0.5	-0.9	0.1	0.1	-1.2	-0.4
Angina	0.2	0.3	1.1	0.2	-0.0	0.5	0.2	1.1	-1.1	-0.2	0.2	-0.6	0.2
Diabetes (father)	0.2	0.3	1.1	0.3	0.5	-1.0	0.2	0.3	-0.9	-0.1	0.5	-0.4	0.1
Pack years adult smoking proportion	0.2	0.3	0.7	0.8	0.4	0.5	0.7	0.4	0.1	-0.2	0.4	0.7	0.3
Average weekly fortified wine intake	0.2	0.3	0.7	-0.1	-0.7	-0.8	-0.3	-0.3	-0.9	-0.6	-0.5	-0.2	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.2	-0.0	0.7	1.0	0.3	0.2	0.4	-0.1	0.5	0.8	1.1
Hayfever, allergic rhinitis or eczema	0.2	0.4	2.9	0.0	0.2	1.7	0.2	0.7	0.6	0.2	0.5	-0.3	0.5
Multivitamins +/- minerals	0.2	0.2	1.0	-0.1	0.2	1.0	-0.3	0.6	-0.4	0.4	0.6	-0.2	0.2
Sitting height	0.2	1.3	2.9	1.1	1.5	0.5	0.7	0.6	-0.6	1.2	1.4	1.7	1.4
Waist circumference	0.2	0.7	3.2	0.4	-0.9	0.0	1.0	-0.7	-0.3	0.3	-0.9	1.8	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.6	-0.0	-0.1	-0.4	-0.4	0.5	-0.8	-0.6	0.3	-1.2	0.2
Fluid intelligence score	0.2	0.5	2.9	0.7	0.2	-0.2	0.2	-0.3	-0.3	0.9	-0.4	1.7	-0.5
Qualifications: A levels/AS levels or equivalent	0.2	0.5	2.8	-0.2	0.3	1.2	-0.3	-1.7	0.2	-0.1	-0.2	0.5	-0.0
Exposure to tobacco smoke at home	0.2	0.2	0.9	0.2	-0.0	0.1	0.1	-0.5	0.5	-0.9	-0.2	0.6	0.7
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.9	0.9	0.7	-0.1	-0.3	-0.1	0.8	0.1	0.6	0.5	0.5
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.3	0.0	0.6	1.2	0.2	-0.3	-0.0	0.6	0.5	-0.2	0.7
Exposure to tobacco smoke outside home	0.2	0.3	2.1	-0.1	-0.6	0.4	-0.1	0.3	-1.5	0.4	-0.4	-0.2	-0.3
Mean time to correctly identify matches	0.2	0.5	2.8	0.1	0.2	0.2	0.4	0.8	0.3	1.7	0.4	-0.5	-0.6
Number of full sisters	0.2	0.2	1.4	-0.7	-0.2	0.4	-0.0	0.4	-0.5	0.0	0.3	-1.2	-0.1
Family relationship satisfaction	0.2	0.2	0.8	0.2	0.1	-0.9	-0.6	-0.1	-0.3	0.7	0.3	0.6	0.3
Long-standing illness, disability or infirmity	0.2	0.3	0.8	0.0	-0.6	-0.9	0.4	0.7	-0.7	-0.5	0.0	-0.7	0.4
Ever had bowel cancer screening	0.2	0.3	0.7	0.5	0.4	-0.5	0.7	0.8	0.4	0.1	0.6	0.2	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	0.8	-0.3	-0.2	0.1	-0.8	0.6	-0.5	0.5	0.3	-0.9	-0.3
Medication for cholesterol	0.2	0.4	1.6	-0.2	-0.0	1.3	-0.8	-0.1	-0.7	0.9	0.3	0.1	0.1
Irritability	0.2	0.3	1.0	0.4	0.8	-0.2	-0.1	1.0	-0.1	-0.4	0.5	-0.4	0.7
Diastolic blood pressure, automated reading	0.2	0.7	3.5	0.5	-0.1	-0.7	-0.0	-0.1	1.9	-0.3	-0.8	1.0	-1.0
Commuting to job workplace: Cycle	0.2	0.2	0.5	-0.3	-0.3	-0.0	-0.4	0.1	-0.4	-0.3	-0.7	-0.7	-0.6
Bipolar Disorder (2018)	0.1	0.2	0.8	-0.4	-0.1	0.3	-0.5	-0.6	0.3	-0.9	0.0	-0.8	0.0
Blood Eosinophil Count	0.1	1.1	4.3	-0.5	-0.9	2.1	-0.8	1.0	0.7	-1.3	-1.0	-0.6	-0.7
Blood Platelet Count	0.1	1.5	11.8	-0.2	-0.3	3.4	-0.0	0.9	1.2	-0.2	-0.2	-0.5	-0.7
Heel T-Score	0.1	0.4	1.2	-0.4	0.4	1.1	-0.5	0.2	-0.7	0.6	0.3	0.8	0.9
Hand grip strength (left)	0.1	0.4	2.4	0.5	0.5	-0.5	-0.2	-0.1	-0.6	-0.2	-0.3	1.6	-0.1
Hand grip strength (right)	0.1	0.3	1.0	-0.5	-0.3	0.0	-0.7	-0.6	-0.7	-1.0	-0.6	0.1	-0.4
Taking other prescription medications	0.1	0.2	1.1	0.4	-0.0	-0.4	1.0	0.3	0.4	-0.1	0.1	-0.3	0.3
Bilateral oophorectomy (both ovaries removed)	0.1	0.2	0.4	-0.7	-0.5	0.1	-0.4	0.2	0.3	-0.4	-0.4	-0.5	0.2
Hearing difficulty/problems with background noise	0.1	0.2	0.8	0.6	0.6	-0.0	0.2	0.4	0.2	0.1	0.9	-0.2	0.5
Had other major operations	0.1	0.1	0.2	0.2	-0.0	0.2	-0.4	-0.3	-0.2	-0.5	-0.2	0.4	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.7	-0.5	0.2	1.3	-0.3	-0.1	-0.5	0.4	-0.0	0.6	0.3
Hair/balding pattern: Pattern 3	0.1	0.2	0.9	0.1	-0.1	-0.9	0.2	-0.6	-0.2	0.4	-0.0	0.4	-0.6
Prospective memory result	0.1	0.2	0.7	-0.2	-0.2	-0.5	-0.9	0.4	-0.6	0.3	-0.1	-0.2	-0.2
Had major operations	0.1	0.2	0.6	0.2	0.2	-0.5	0.8	0.0	0.6	0.1	0.4	-0.1	0.5
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.3	0.1	-0.2	-0.5	0.3	-0.2	-0.1	-0.4	-0.2	0.1	-0.2
Medication: Gliclazide	0.1	0.1	0.5	0.0	-0.3	0.3	0.0	-0.3	-0.5	0.6	-0.1	0.3	-0.7
Average weekly champagne plus white wine intake	0.1	0.1	0.5	-0.4	0.0	-0.1	-0.0	-0.6	-0.1	-0.2	-0.1	-0.5	-0.7
Basal cell carcinoma (self-reported)	0.1	0.2	0.5	-0.6	-0.3	0.2	-0.7	0.1	0.2	-0.3	-0.2	-0.6	0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.7	1.8	0.6	1.0	0.7	-0.1	1.3	0.8	-0.2	1.0	0.7	1.4
Tanning	0.0	0.1	1.2	0.0	-0.2	1.1	-0.3	0.1	0.1	0.2	0.1	-0.2	0.1
Guilty feelings	0.0	0.1	0.2	-0.1	-0.0	0.3	0.3	-0.2	0.1	-0.2	-0.2	-0.4	-0.3

Hub : Genes

DNASE1

Models

Trait associations