[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), predicted percentage :

chr17:72,819,004-74,267,010

Best TWAS P=1.9e-09 · Best GWAS P=3.32e-09 conditioned to 0.359

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa TSEN54 0.12 0.00 lasso 5 0.00 3.0e-01 4.4 -5.5 4.2e-08 -0.58 0.02 0.88 FALSE
2 GTEx Esophagus Muscularis LLGL2 0.23 0.17 lasso 4 0.17 2.0e-10 5.9 6.0 2.1e-09 0.97 0.00 1.00 FALSE
3 GTEx Heart Left Ventricle LLGL2 0.23 0.09 lasso 5 0.11 2.5e-06 5.9 6.0 1.9e-09 0.93 0.00 1.00 TRUE
4 GTEx Muscle Skeletal LLGL2 0.22 0.08 lasso 8 0.08 4.3e-08 5.9 5.9 3.1e-09 0.97 0.00 1.00 FALSE
5 GTEx Thyroid LLGL2 0.08 0.04 lasso 3 0.04 4.7e-04 5.7 5.2 2.5e-07 0.85 0.01 0.90 FALSE