Best TWAS P=3.04e-13 · Best GWAS P=1.67e-14 conditioned to 0.0103
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | MICAL3 | 0.23 | 0.06 | lasso | 4 | 0.03 | 2.7e-02 | 7.1 | -7.1 | 1.8e-12 | -0.83 | 0.11 | 0.24 | FALSE |
| 2 | GTEx | Thyroid | MICAL3 | 0.18 | 0.13 | enet | 18 | 0.13 | 6.5e-10 | -5.6 | -6.4 | 1.9e-10 | -0.75 | 0.25 | 0.75 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | MICAL3 | 0.10 | 0.06 | enet | 14 | 0.04 | 1.5e-03 | 7.6 | -7.3 | 3.0e-13 | -0.90 | 0.01 | 0.98 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | MICAL3 | 0.10 | 0.09 | enet | 14 | 0.10 | 1.4e-09 | -5.6 | -5.9 | 3.9e-09 | -0.71 | 0.26 | 0.74 | FALSE |