[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), predicted percentage :

chr22:17,581,838-19,203,078

Best TWAS P=3.04e-13 · Best GWAS P=1.67e-14 conditioned to 0.0103

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells EBV-transformed lymphocytes MICAL3 0.23 0.06 lasso 4 0.03 2.7e-02 7.1 -7.1 1.8e-12 -0.83 0.11 0.24 FALSE
2 GTEx Thyroid MICAL3 0.18 0.13 enet 18 0.13 6.5e-10 -5.6 -6.4 1.9e-10 -0.75 0.25 0.75 FALSE
3 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma MICAL3 0.10 0.06 enet 14 0.04 1.5e-03 7.6 -7.3 3.0e-13 -0.90 0.01 0.98 TRUE
4 The Cancer Genome Atlas Thyroid Carcinoma MICAL3 0.10 0.09 enet 14 0.10 1.4e-09 -5.6 -5.9 3.9e-09 -0.71 0.26 0.74 FALSE