Best TWAS P=1.91e-11 · Best GWAS P=1.18e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ARFRP1 | 0.07 | 0.07 | lasso | 3 | 0.06 | 5.3e-08 | 6.6 | -6.3 | 3.4e-10 | -0.96 | 0.01 | 0.99 | FALSE |
| 2 | METSIM | Adipose | TPD52L2 | 0.03 | 0.00 | bslmm | 207 | 0.02 | 1.5e-03 | -4.0 | -6.7 | 2.5e-11 | -0.68 | 0.02 | 0.74 | FALSE |
| 3 | YFS | Blood | LIME1 | 0.12 | 0.19 | enet | 15 | 0.19 | 5.3e-59 | 6.7 | 6.7 | 1.9e-11 | 0.98 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | TNFRSF6B | 0.02 | 0.01 | enet | 7 | 0.01 | 6.9e-03 | 4.4 | 5.8 | 5.4e-09 | 0.93 | 0.02 | 0.89 | FALSE |
| 5 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | RTEL1 | 0.05 | 0.04 | blup | 56 | 0.03 | 4.2e-03 | 5.2 | 5.8 | 7.0e-09 | 0.88 | 0.01 | 0.80 | FALSE |
| 6 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | TNFRSF6B | 0.05 | 0.02 | blup | 44 | 0.03 | 2.9e-03 | 6.8 | 6.6 | 3.6e-11 | 0.93 | 0.01 | 0.74 | FALSE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ARFRP1 | 0.03 | 0.02 | lasso | 2 | 0.02 | 1.2e-03 | 6.6 | -6.6 | 3.1e-11 | -0.98 | 0.01 | 0.97 | FALSE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | LIME1 | 0.04 | 0.05 | blup | 47 | 0.05 | 9.0e-06 | 6.7 | 6.4 | 1.8e-10 | 0.97 | 0.01 | 0.99 | FALSE |
| 9 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SLC2A4RG | 0.05 | 0.01 | blup | 48 | 0.02 | 2.0e-03 | 6.7 | -6.4 | 1.4e-10 | -0.85 | 0.01 | 0.95 | FALSE |
| 10 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | LIME1 | 0.10 | 0.02 | blup | 47 | 0.04 | 1.5e-02 | 6.7 | 5.7 | 1.5e-08 | 0.90 | 0.01 | 0.64 | FALSE |
| 11 | The Cancer Genome Atlas | Thyroid Carcinoma | ARFRP1 | 0.04 | 0.00 | blup | 51 | 0.00 | 1.3e-01 | 6.7 | -6.1 | 1.0e-09 | -0.81 | 0.01 | 0.60 | FALSE |