Best TWAS P=5.31e-11 · Best GWAS P=5.39e-12 conditioned to 0.000518
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | CTTNBP2 | 0.12 | 0.08 | lasso | 7 | 0.09 | 6.0e-07 | -6.6 | -6.1 | 1.0e-09 | -0.66 | 0.02 | 0.96 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | CTTNBP2 | 0.14 | 0.10 | lasso | 2 | 0.08 | 2.4e-07 | -6.6 | -6.6 | 5.3e-11 | -0.65 | 0.02 | 0.98 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CTTNBP2 | 0.03 | 0.01 | blup | 90 | 0.01 | 1.0e-02 | -5.5 | -5.5 | 2.8e-08 | -0.34 | 0.18 | 0.25 | FALSE |