Hub : Genes

CTTNBP2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0460	0.0230	4.8e-03	0.011	0.016	0.019	0.018	0.010	1.6e-02	0.0038	2.0e-03	0.0027	2.1e-02
2	GTEx	Cells Transformed fibroblasts	0.1190	0.0440	6.7e-04	0.080	NA	0.071	NA	0.085	1.4e-06	NA	5.3e-06	NA	6.0e-07
3	GTEx	Nerve Tibial	0.0933	0.0394	1.3e-03	-0.002	NA	0.022	NA	-0.003	5.1e-01	NA	9.7e-03	NA	5.5e-01
4	GTEx	Skin Sun Exposed Lower leg	0.1410	0.0430	2.4e-05	0.102	NA	0.073	NA	0.083	9.3e-09	NA	1.2e-06	NA	2.4e-07
5	GTEx	Testis	0.1930	0.0830	6.7e-03	0.103	NA	0.040	NA	0.066	2.6e-05	NA	7.0e-03	NA	7.0e-04
6	GTEx	Thyroid	0.1370	0.0540	1.2e-03	0.101	NA	0.089	NA	0.093	3.8e-08	NA	2.5e-07	NA	1.3e-07
7	TCGA	Breast Invasive Carcinoma	0.0296	0.0143	2.5e-03	0.012	0.007	0.004	NA	0.006	1.4e-03	0.0100	4.1e-02	NA	2.1e-02
8	TCGA	Thyroid Carcinoma	0.0580	0.0280	3.9e-03	0.028	0.022	0.011	NA	0.007	8.2e-04	0.0027	2.7e-02	NA	5.9e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	1.2	1.9	6.5	0.6	2.5	1.0	1.9	1.1	0.3	1.3	1.0
Bipolar Disorder or Schizophrenia	0.4	1.0	4.0	-0.7	2.0	-0.6	1.5	-0.0	0.3	0.6	-0.1
Depressed Affect (Nagel 2018)	3.3	7.0	15.8	-1.0	-3.8	-1.7	-4.0	-2.0	-0.6	-3.5	-2.2
Depression (Nagel 2018)	1.6	2.3	4.8	-0.1	-1.8	-1.5	-1.9	-0.6	-1.3	-1.7	-2.2
Intelligence (Savage-Jansen 2018)	0.8	2.5	7.5	0.2	0.4	2.7	0.2	2.6	0.2	1.1	2.0
Neuroticism (Nagel 2018)	3.3	7.8	19.7	-1.6	-4.4	0.5	-4.4	-1.7	-0.7	-4.0	-1.3
Schizophrenia (2018)	0.4	0.8	2.4	-1.3	0.5	-1.5	0.4	-1.0	0.2	-0.3	-0.7
Schizophrenia vs Biploar Disorder	2.8	3.7	6.5	-1.9	-1.4	-2.5	-0.6	-2.3	-1.1	-2.2	-2.4
Worry (Nagel 2018)	1.5	3.1	7.7	-1.6	-2.1	1.6	-1.9	-0.5	-1.3	-2.8	-1.3
Alzheimer’s Disease (in mother)	1.0	1.2	2.7	-0.6	-1.7	-0.1	-1.6	-0.6	1.5	-1.0	-0.1
Alzheimer’s Disease (in father)	0.3	0.3	1.0	0.2	1.0	0.3	0.4	0.0	-0.1	0.7	1.0
Alzheimer’s Disease (including proxy)	0.2	0.3	0.7	-0.5	-0.8	0.5	-0.9	-0.3	0.4	-0.3	-0.0
Crohns Disease (2017)	0.7	1.5	5.1	2.3	-0.6	-2.0	-0.8	-0.5	0.0	-0.8	-1.0
Irritable Bowel Disease (IBD)	0.5	1.3	4.3	2.1	0.5	-2.0	0.5	-0.5	-0.3	-0.1	-0.9
Ulcerative Colitis (UC)	0.3	0.6	1.5	0.6	0.6	-1.2	0.8	-0.7	-0.9	-0.1	-0.8
Major Depression (MDD)	8.1	9.9	22.3	-3.8	-3.5	1.0	-3.8	-3.4	0.9	-4.7	-1.5
Reaction Time	0.5	0.9	3.1	-0.2	-0.6	-0.1	-0.7	-1.1	-1.3	0.3	-1.8
Verbal and Numeric Reasoning (VNR)	0.4	0.9	3.7	-0.0	-0.6	1.9	-0.4	1.2	-0.8	0.8	0.4
Breast Cancer	0.3	0.6	2.0	1.1	0.2	-0.9	0.4	-1.4	-0.5	-0.6	-0.5
Ovarian Cancer	1.9	2.5	6.0	-0.6	-2.1	-1.6	-2.4	-2.2	0.6	-1.0	-0.5
Prostate Cancer	0.2	0.3	0.9	0.4	0.7	-0.9	0.5	-0.5	0.5	-0.4	-0.4
Age at First Birth	0.5	0.8	2.9	0.2	1.2	0.9	1.7	-0.4	0.8	0.0	0.7
Bipolar Disorder (2011)	4.1	4.0	9.8	1.1	3.1	2.1	2.1	1.4	1.9	0.9	2.3
Body Mass Index (BMI) (2010)	0.9	1.3	2.8	0.5	1.2	1.0	1.5	1.7	-0.6	0.8	1.1
Coronary Artery Disease (CAD)	1.4	1.7	3.6	-0.5	-1.5	-0.7	-1.9	-0.9	0.2	-1.9	-1.6
Crohns Disease (2012)	0.5	0.7	1.6	0.7	-0.9	-0.7	-0.6	-1.3	0.6	-1.2	-0.5
Mean Putamen Volume	1.2	1.3	2.2	-1.2	1.0	1.5	1.3	0.1	-1.3	0.9	-1.2
Fasting Glucose	0.5	0.7	2.1	1.1	-0.6	-0.8	-1.4	0.0	0.7	-0.6	0.1
HbA1C	0.2	0.2	0.5	0.0	0.4	0.1	0.6	-0.3	-0.2	0.7	0.7
HDL Cholesterol	0.3	0.5	1.7	-0.8	0.0	0.1	0.4	-0.6	-1.3	-0.2	-0.8
LDL Cholesterol	0.6	0.9	4.2	-0.5	-0.5	-2.0	-0.2	-1.3	-0.6	-0.2	-0.0
Lupus	0.9	1.4	3.6	1.6	0.8	-1.1	0.7	1.9	-0.3	1.3	0.9
Neuroticism (2016)	3.0	4.4	10.2	-1.9	-3.2	1.4	-3.2	-1.6	-0.2	-1.8	-1.9
Primary Biliary Cirrhosis	0.4	0.6	1.4	-0.5	-0.5	-0.4	-0.0	-1.2	-0.9	-0.9	-1.2
Rheumatoid Arthritis	2.5	3.4	7.4	-2.1	-2.1	0.9	-1.8	-2.4	0.4	-2.7	-1.1
Schizophrenia (2014)	0.7	1.5	5.0	-0.6	0.2	-1.9	0.7	-1.2	-0.5	-0.5	-2.2
Triglycerides	0.6	0.9	1.9	-0.7	-1.2	-1.1	-1.3	-1.4	-0.3	-0.6	-0.5
Type 2 Diabetes (T2D) (2012)	3.9	4.4	10.7	-2.0	-3.3	1.0	-2.7	-2.4	0.6	-2.4	-0.8
Ulcerative Colitis	0.4	0.6	1.0	-0.6	0.9	-1.0	1.0	-0.9	-0.8	-0.4	-0.7
Blood Eosinophil Count	0.3	2.7	7.2	-2.6	-0.7	2.2	-1.0	-0.7	-0.4	-2.7	0.7
Blood Platelet Count	0.8	9.1	18.1	-0.0	-3.3	-3.3	-2.9	-3.2	-2.0	-3.3	-4.2
Blood Red Count	0.3	3.0	9.2	0.5	1.4	1.1	1.1	3.0	0.5	3.0	1.2
Blood White Count	0.7	5.2	12.6	-0.2	-3.0	-1.5	-2.8	-1.7	-1.3	-2.3	-3.5
Heel T-Score	0.3	2.3	8.8	-0.4	2.9	0.7	3.0	-0.3	-0.1	0.6	0.6
BMI	0.6	3.3	17.6	0.7	-1.3	-4.2	-1.4	-1.0	-0.4	-0.5	-1.8
Height	0.4	8.1	18.7	0.7	4.3	1.2	3.5	2.4	3.3	2.3	3.1
Waist Hip Ratio (WHR)	1.3	5.7	13.4	-0.4	-3.4	-3.7	-2.8	-0.7	-0.3	-1.0	-3.4
Systolic Blood Pressure	0.2	1.0	1.9	-0.7	-1.3	-0.3	-1.2	-0.3	1.4	-0.5	-1.4
Smoking Status	11.1	26.6	55.8	-2.9	-7.1	-3.5	-7.5	-5.5	0.3	-6.2	-4.1
Allergy or Eczema	0.6	1.5	4.3	-0.5	0.7	1.9	0.5	-0.8	0.7	-1.5	2.1
Cardiovascular Disease	0.3	1.1	4.1	2.0	0.4	-0.6	0.5	1.0	-0.5	1.5	-0.9
Hypothyroidism (self reported)	0.6	1.4	2.9	1.7	0.8	-0.6	1.6	0.8	-1.6	1.2	-0.4
Respiratory disease	1.7	3.7	14.4	-1.2	1.8	3.8	2.1	1.1	-1.6	0.8	1.3
Type 2 Diabetes (T2D) (2018)	3.1	5.9	13.8	-2.5	-3.7	-0.4	-3.3	-2.0	-0.8	-2.5	-2.1
Lung FEV1/FVC ratio	2.0	10.0	18.6	0.0	-4.2	-3.3	-4.3	-2.8	-2.0	-3.8	-2.6
Lung FVC	1.0	4.8	13.3	-2.2	-3.6	0.2	-3.4	-2.1	0.1	-2.0	-0.5
Neuroticism	3.6	8.7	20.9	-2.1	-4.3	1.6	-4.6	-1.4	-0.1	-4.5	-1.1
Chronotype (morning person)	1.2	2.7	6.9	-1.0	-2.6	-1.2	-2.5	-1.4	1.6	-1.0	-0.6
Hair Pigment	0.1	1.6	3.6	1.3	0.5	0.2	1.7	0.5	-1.9	1.5	-1.4
Tanning	0.2	2.2	6.3	-0.6	-1.7	-1.8	-1.6	-2.5	-0.4	-1.2	-0.5
Hand grip strength (left)	0.2	0.5	1.5	-1.2	-0.3	0.3	-0.8	0.0	0.7	-0.1	1.1
Number of treatments/medications taken	0.1	0.1	0.3	-0.3	-0.3	-0.3	-0.2	-0.6	-0.4	-0.3	-0.3
Average weekly spirits intake	1.3	1.6	3.1	0.9	-1.5	-1.2	-1.8	-0.6	1.6	-1.4	-0.1
Sensitivity / hurt feelings	1.7	2.9	8.0	0.9	-2.8	-0.0	-2.6	-1.2	0.4	-2.0	-1.1
Frequency of depressed mood in last 2 weeks	2.9	4.0	8.4	-1.1	-2.9	-1.0	-2.7	-0.9	-1.5	-2.2	-2.5
Hearing difficulty/problems: Yes	1.4	2.2	5.1	1.3	1.6	0.4	2.3	0.4	-2.0	1.3	-1.3
Relative age of first facial hair	0.3	0.6	2.2	-1.5	0.3	1.4	-0.3	-0.2	0.4	-0.5	-0.0
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.1	-0.7	0.1	-1.1	0.4	-0.7	0.1	-0.6	-0.5
Ever used hormone-replacement therapy (HRT)	0.8	1.0	4.7	-0.1	-0.1	1.1	-0.2	-2.2	0.0	-1.2	0.6
Ever had hysterectomy (womb removed)	0.6	0.7	2.2	1.5	-1.1	-0.4	-0.8	-1.0	0.4	-0.2	0.3
Systolic blood pressure, automated reading	0.4	1.3	3.2	0.2	1.5	0.6	1.2	0.8	1.5	1.8	0.3
Eye problems/disorders: Diabetes related eye disease	3.3	3.6	10.9	0.6	-0.6	-3.1	0.3	-0.7	-2.5	0.8	-3.3
Angina	2.1	2.8	8.8	3.0	0.5	-0.9	1.3	1.1	-1.6	1.2	-2.4
Medication for hormone replacement therapy	0.8	0.9	2.5	-0.8	-1.0	-0.7	-0.6	-1.5	0.1	-1.6	-0.4
Vitamin and mineral supplements	0.5	0.7	1.4	0.8	1.2	-0.1	0.9	0.7	-0.7	0.5	-1.2
Supplements: Zinc	3.3	3.6	6.0	-0.8	2.5	2.3	2.4	1.9	0.2	1.8	2.1
Medication: Co-codamol	1.4	1.6	2.8	0.4	-1.2	-0.9	-1.6	-1.5	-1.2	-0.9	-1.7
Medication: Metformin	3.5	5.0	14.8	-1.6	-3.9	-0.5	-3.1	-2.3	0.4	-2.0	-1.7
Diabetes (father)	0.3	0.4	1.1	-0.6	-0.6	1.0	-0.3	-0.7	-0.5	-0.3	-0.5
Diabetes (mother)	1.8	2.3	6.9	0.2	-2.6	-2.3	-2.3	0.6	-0.7	-0.6	0.0
Severe depression (siblings)	1.6	1.8	5.2	-1.2	-1.8	-0.6	-2.3	-1.2	0.7	-1.5	-0.3
Pack years adult smoking proportion	1.1	1.7	4.5	-0.5	-1.8	-0.5	-2.1	-0.8	1.4	-1.6	0.4
Impedance of leg (right)	0.1	0.4	1.3	-0.5	-0.1	0.9	-0.2	0.3	-1.1	-0.5	-0.7
Leg fat-free mass (left)	0.2	1.2	6.3	0.2	0.3	-2.5	0.1	-1.1	1.4	-0.1	-0.4
Trunk fat percentage	0.5	2.0	8.2	2.1	-0.5	-2.9	-0.3	0.1	-1.0	0.7	-1.1
Hand grip strength (right)	0.3	0.8	2.3	-1.0	0.4	0.7	-0.3	0.9	0.9	0.8	1.5
Townsend deprivation index at recruitment	5.6	7.9	22.3	-1.5	-4.5	-1.7	-4.7	-2.0	-0.6	-2.8	-1.5
Current tobacco smoking	7.7	12.6	29.3	-2.5	-4.8	-2.2	-5.4	-3.5	0.8	-4.7	-1.6
Average weekly fortified wine intake	3.1	3.6	6.5	1.3	2.5	2.6	2.2	1.5	0.2	2.0	1.8
Maternal smoking around birth	2.6	3.7	8.4	-1.4	-2.9	-1.4	-2.9	-1.5	-0.2	-2.0	-1.7
Fed-up feelings	6.4	11.7	28.9	-0.8	-5.4	-1.6	-4.9	-2.7	-1.3	-3.9	-3.6
Frequency of unenthusiasm / disinterest in last 2 weeks	7.2	9.7	16.9	-1.6	-3.8	-2.6	-3.7	-3.2	-1.4	-3.3	-4.1
Relative age voice broke	0.9	1.4	6.5	-1.7	0.1	2.6	0.2	1.4	-0.2	0.3	-0.1
Taking other prescription medications	0.8	1.2	3.3	-0.8	-0.5	-0.5	0.0	-1.4	-1.7	-0.8	-1.8
Age when periods started (menarche)	0.6	1.4	3.3	1.7	1.8	0.3	1.8	0.5	0.9	0.2	1.0
Bilateral oophorectomy (both ovaries removed)	2.0	2.3	5.6	2.4	1.3	-1.0	1.5	1.6	0.7	1.5	1.5
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.8	-0.3	1.1	0.5	1.3	0.5	-0.8	1.1	-0.1
Tinnitus: Yes, but not now, but have in the past	1.0	1.0	3.2	1.3	-0.3	-1.1	0.4	0.3	-1.1	0.8	-1.8
Qualifications: CSEs or equivalent	0.4	0.6	1.9	-0.4	-0.0	-0.4	-0.3	-1.1	-0.3	-1.4	-0.9
Serious illness, injury or assault to yourself	1.9	2.3	8.3	-1.3	-2.9	-0.6	-2.2	-1.0	-0.0	-1.1	-0.9
High blood pressure	0.9	2.4	8.8	2.0	0.3	-1.1	0.4	1.6	-0.8	3.0	-1.5
Hayfever, allergic rhinitis or eczema	0.4	0.9	2.6	-0.9	-0.3	1.0	-0.2	-1.5	-0.3	-1.6	0.5
Multivitamins +/- minerals	0.7	0.9	2.2	-1.4	-1.1	1.5	-0.7	-0.3	0.3	-0.5	1.0
Stomach or abdominal pain in last month	0.3	0.3	1.1	-0.1	-1.1	0.4	-0.7	0.1	-0.6	-0.8	0.1
Supplements: Glucosamine	1.0	1.3	3.1	1.0	1.8	0.5	1.7	1.0	0.1	1.4	0.2
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	3.8	0.9	-1.2	-0.4	-0.6	-0.2	-1.9	-0.0	-1.9
Medication: Atenolol	0.3	0.4	1.3	-0.6	-0.7	-0.1	-0.7	-0.7	-0.3	0.2	-1.2
Medication: Levothyroxine sodium	0.3	0.5	1.2	0.8	0.4	-1.1	0.5	0.1	-0.8	-0.3	-0.8
Sitting height	0.8	5.6	12.5	0.9	3.3	1.8	2.1	1.7	3.1	0.4	3.5
Chronic bronchitis/emphysema (father)	2.0	2.4	4.3	-2.1	-2.0	-0.2	-1.9	-0.9	1.5	-2.0	-0.6
High blood pressure (mother)	0.4	0.5	1.6	-0.5	-1.0	0.1	-0.6	-0.4	-0.5	-0.8	-1.3
Body mass index (BMI)	0.8	3.4	17.2	1.0	-1.6	-4.2	-1.2	-1.4	-0.5	-0.3	-1.8
Impedance of leg (left)	0.1	0.4	1.6	-0.0	0.1	1.0	0.0	0.7	-1.3	-0.2	-0.4
Leg predicted mass (left)	0.2	1.1	6.1	0.2	0.2	-2.5	0.1	-1.1	1.3	-0.1	-0.4
Trunk fat mass	0.5	2.0	11.3	1.8	-0.3	-3.4	-0.2	-0.1	-0.2	0.6	-1.0
Waist circumference	0.9	3.2	19.5	0.8	-1.2	-4.4	-0.9	-0.8	0.4	0.2	-1.5
Number of incorrect matches in round	2.6	4.4	8.9	2.4	3.0	-0.0	2.7	2.2	-0.6	2.7	0.4
Past tobacco smoking	5.4	9.9	23.4	1.0	4.2	1.3	4.8	3.5	-1.5	4.4	1.5
Alcohol usually taken with meals	9.7	15.7	29.9	2.9	5.5	2.3	5.0	3.9	1.4	5.3	3.5
Nervous feelings	2.1	3.9	6.6	-2.3	-2.6	1.1	-1.7	-1.1	-1.5	-2.5	-2.3
Frequency of tenseness / restlessness in last 2 weeks	1.7	2.7	8.7	-0.2	-2.0	0.6	-1.3	0.1	-3.0	-0.9	-2.4
Hearing difficulty/problems with background noise	0.6	0.9	3.7	-0.9	-0.5	0.8	0.2	-0.2	-1.3	-0.1	-1.9
Hair/balding pattern: Pattern 2	2.1	2.7	8.7	0.6	1.2	1.3	1.3	1.5	-3.0	2.2	-0.7
Had menopause	1.2	1.5	2.6	1.6	1.5	0.4	1.1	0.8	1.3	1.6	1.1
Had other major operations	0.5	0.6	1.8	0.2	0.2	1.3	-0.2	0.7	0.5	0.1	1.4
Forced vital capacity (FVC)	1.1	4.3	8.9	-2.6	-2.4	0.5	-2.7	-2.2	-0.1	-3.0	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	4.4	-0.6	0.8	-0.1	1.1	0.3	-2.1	1.1	-1.2
Ever unenthusiastic/disinterested for a whole week	2.2	2.6	7.8	-1.5	-1.9	-0.2	-2.0	-1.4	0.5	-2.8	-1.2
Qualifications: None of the above	1.6	3.4	8.3	-0.3	-2.6	-2.5	-2.9	-1.3	-0.2	-1.2	-1.6
Financial difficulties in last 2 years	4.7	6.3	12.7	-1.6	-3.6	-2.1	-3.0	-2.3	-1.5	-2.2	-3.1
Mouth/teeth dental problems	1.8	2.7	11.6	-1.1	1.7	3.4	1.0	1.3	0.5	0.4	1.7
Heart attack	1.7	2.1	9.1	1.0	-0.9	-0.7	0.3	0.5	-2.1	1.1	-3.0
Allergy	0.4	0.9	3.6	1.1	0.2	-1.9	0.1	0.1	0.8	0.9	-0.8
Pain all over the body in last month	1.0	1.1	2.3	-0.1	-1.2	-0.7	-1.5	-1.5	0.3	-1.4	0.4
Diabetes (self-reported)	2.9	4.4	13.0	-1.5	-3.6	-0.4	-3.2	-1.4	-0.1	-1.8	-2.1
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	2.5	-1.6	-0.4	0.6	-0.3	-0.1	-0.1	0.0	0.3
Medication: Ramipril	1.4	1.8	5.7	0.7	-1.9	-2.4	-1.5	0.4	-0.4	0.3	-1.3
Medication: Simvastatin	0.6	0.9	3.1	1.8	0.6	0.3	0.7	1.3	-0.1	1.0	0.3
Fluid intelligence score	0.3	0.6	1.7	-0.6	-0.8	1.3	-0.5	0.0	-1.2	-0.8	-0.3
Illnesses of siblings	0.8	1.1	2.6	-0.0	1.2	1.3	1.1	0.8	-1.0	1.6	0.5
Neuroticism score	4.0	8.3	20.1	-1.5	-4.5	0.3	-4.1	-1.8	-0.5	-4.2	-2.5
Weight	0.4	2.0	13.4	1.0	-0.1	-3.7	-0.2	-0.7	0.7	0.2	-0.8
Impedance of arm (right)	0.3	1.2	6.1	-0.6	-0.5	2.5	-0.8	-0.1	-0.6	-1.2	0.5
Arm fat percentage (right)	0.8	3.1	10.8	1.1	-1.9	-3.3	-1.7	-1.4	-0.8	-0.9	-1.7
Trunk fat-free mass	0.3	1.6	6.0	0.3	1.5	-2.5	1.2	-0.4	1.6	0.5	0.0
Hip circumference	0.3	1.5	10.7	0.5	0.2	-3.3	0.4	-0.5	0.5	0.5	0.0
Time employed in main current job	2.1	2.4	5.7	1.8	2.4	-0.7	2.4	1.1	-0.3	1.6	0.5
Alcohol intake versus 10 years previously	3.0	4.4	11.2	-1.3	-3.0	-1.0	-3.4	-2.0	-0.9	-2.7	-0.8
Father’s age at death	3.6	4.8	9.3	1.1	3.0	1.1	2.7	2.1	-0.6	2.6	2.8
Worrier / anxious feelings	1.8	3.4	7.4	-1.9	-2.7	1.8	-2.6	-0.1	0.4	-2.2	-0.8
Frequency of tiredness / lethargy in last 2 weeks	3.2	5.3	11.9	-1.2	-2.9	-1.0	-2.2	-2.1	-2.0	-2.5	-3.5
Falls in the last year	2.2	3.0	6.9	0.2	-2.6	-0.9	-2.6	-0.9	-1.9	-0.8	-2.2
Hair/balding pattern: Pattern 3	0.2	0.2	0.8	0.9	0.4	-0.5	0.6	0.1	-0.5	0.2	0.0
Number of live births	0.5	0.6	1.7	-0.3	-1.1	-0.2	-1.3	-0.8	0.2	-1.2	-0.2
Forced expiratory volume in 1-second (FEV1)	2.1	7.2	15.2	-2.7	-3.4	-0.1	-3.8	-2.9	-0.5	-3.9	-0.8
Pulse rate	0.6	1.1	3.2	0.6	0.2	-1.2	0.6	0.3	-1.6	0.8	-1.8
Happiness	2.1	2.6	9.9	1.2	0.9	-0.3	1.4	0.4	-3.1	-0.1	-2.5
Noisy workplace	1.8	2.3	6.6	0.8	-1.5	-2.5	-0.9	-0.5	-1.1	0.3	-2.6
Qualifications: A levels/AS levels or equivalent	2.2	4.9	12.0	0.9	3.5	2.7	3.4	1.5	1.3	0.6	1.7
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.2	-0.5	-1.5	1.2	-1.1	-0.0	0.6	-0.9	0.4
Mouth/teeth dental problems: Dentures	2.1	3.6	15.3	2.1	-1.4	-3.9	-1.0	-0.5	-1.8	-0.0	-1.6
Asthma	1.3	2.5	13.7	-1.5	0.4	3.7	0.5	0.9	-1.6	0.3	0.4
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	3.7	1.0	-0.5	0.0	-1.2	-0.8	1.9	-1.5	1.4
Medication: Cholesterol lowering	0.6	1.0	4.1	0.7	-0.4	-0.7	0.3	-0.3	-1.5	0.6	-2.0
Depression (self-reported)	1.1	1.4	3.0	-0.0	-1.7	0.1	-1.7	-1.1	0.2	-1.5	-1.2
Medication: Lansoprazole	0.9	1.1	3.2	0.6	1.0	0.4	1.4	-0.2	-1.8	0.5	-1.3
Prospective memory result	1.6	2.0	5.0	0.6	2.2	-0.8	2.2	-0.6	-2.0	-0.0	-1.1
Lung cancer (father)	2.5	2.9	4.2	-1.2	-2.0	-1.5	-1.6	-1.9	-1.5	-2.0	-1.7
Illnesses of mother	0.6	0.8	2.5	-0.5	1.6	0.8	1.6	0.0	-0.0	-0.2	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.1	6.0	-1.7	-2.3	-0.3	-2.5	-1.8	-1.1	-2.4	-0.8
Pulse wave Arterial Stiffness index	0.7	0.8	2.5	-0.5	-0.9	-1.6	-1.0	-0.4	1.4	0.1	-0.0
Impedance of arm (left)	0.3	1.3	8.6	-0.0	0.2	2.9	-0.0	0.8	-0.6	-0.3	0.8
Arm fat mass (right)	0.8	3.1	15.8	1.2	-1.2	-4.0	-1.1	-1.4	-0.1	-0.6	-1.6
Trunk predicted mass	0.3	1.5	5.7	0.2	1.3	-2.4	1.1	-0.5	1.7	0.3	-0.0
Standing height	0.3	2.9	8.3	0.4	2.9	0.2	2.0	1.0	2.5	1.0	1.7
Length of working week for main job	1.9	2.1	8.9	-0.3	-3.0	-0.2	-2.1	-0.7	-0.1	-1.3	-1.1
Exposure to tobacco smoke at home	5.6	6.3	15.2	0.7	-2.4	-3.9	-2.2	-2.9	-1.2	-2.0	-3.2
Breastfed as a baby	3.3	4.1	7.3	2.0	2.7	0.3	2.7	1.7	2.3	2.1	1.3
Tense / ‘highly strung’	0.9	1.6	5.5	-0.8	-0.8	2.4	-0.5	1.4	-1.6	-0.5	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	7.0	10.8	23.8	-2.5	-4.6	-0.2	-4.9	-3.2	0.8	-4.6	-1.4
Hair/balding pattern: Pattern 4	0.4	0.9	2.4	-1.6	-1.4	-0.5	-1.0	-0.2	1.2	-0.7	-0.0
Birth weight of first child	1.1	2.0	5.0	1.5	1.0	0.7	1.1	2.2	0.1	2.1	1.2
Peak expiratory flow (PEF)	2.7	6.2	15.8	-1.8	-3.5	0.8	-4.0	-2.3	0.4	-3.5	0.0
Pulse wave reflection index	1.4	1.8	7.3	0.7	-0.5	-2.7	-1.0	-0.2	1.9	-0.5	1.1
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.6	0.6	-0.3	-0.0	-0.5	0.7	-1.3	-0.1	-0.2
Loud music exposure frequency	1.6	1.7	3.7	-1.7	-0.4	0.4	-0.4	-1.9	-1.1	-1.8	-1.5
Qualifications: O levels/GCSEs or equivalent	2.6	4.1	9.1	1.7	2.6	1.6	2.5	3.0	0.5	1.4	1.6
Mouth/teeth dental problems: Bleeding gums	1.2	1.6	5.2	0.2	-1.4	-2.3	-1.0	-1.4	0.0	-0.9	-1.3
Blood clot in the leg (DVT)	0.3	0.3	1.7	0.2	-0.5	-0.2	-1.3	0.5	0.5	-0.1	0.3
Medication: Paracetamol	2.3	3.8	6.8	-0.6	-2.2	-1.6	-2.6	-2.2	1.7	-2.6	-1.1
Headache pain in last month	0.6	1.0	4.0	-0.1	-1.1	-0.4	-0.7	-1.2	-0.5	-0.9	-2.0
Medication for cholesterol, blood pressure or diabetes	1.1	1.9	4.6	-1.2	-0.3	0.5	-1.2	-0.5	1.8	-2.1	1.9
Glaucoma (self-reported)	2.3	2.7	9.0	-0.6	-2.9	-1.0	-3.0	-0.7	0.6	-1.4	-0.5
Gout (self-reported)	0.7	1.0	3.8	0.1	0.2	-1.9	0.2	-1.2	0.9	-1.4	0.3
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	1.8	1.4	0.7	-0.3	1.2	1.1	-1.0	0.6	-0.1
Medication: Amlodipine	1.1	1.5	5.2	-0.1	0.6	-1.8	1.4	-0.7	-0.2	0.7	-2.3
Medication: Ventolin 100micrograms inhaler	1.1	1.4	4.9	0.4	1.0	1.1	0.4	2.2	-0.6	1.4	1.1
Birth weight	0.6	1.3	4.9	0.7	-0.8	-2.2	-0.7	-0.8	-0.7	-0.8	-1.3
Chronic bronchitis/emphysema (mother)	0.2	0.3	0.6	0.2	0.5	-0.3	-0.1	0.5	0.7	0.7	0.7
High blood pressure (siblings)	0.3	0.5	1.3	-1.1	-0.6	0.2	-0.5	-0.2	0.8	-1.1	-0.1
Forced vital capacity (FVC), Best measure	0.4	1.5	3.0	-1.2	-1.7	0.3	-1.7	-1.0	-1.1	-1.4	-0.7
Body fat percentage	0.6	2.2	10.3	1.5	-1.1	-3.2	-0.8	-0.4	-0.9	0.3	-1.5
Leg fat percentage (right)	0.9	3.2	14.3	0.8	-1.9	-3.8	-1.6	-1.0	-0.5	-0.3	-1.8
Arm fat-free mass (right)	0.4	2.1	8.7	1.0	1.2	-3.0	1.0	0.1	2.0	1.1	0.1
Exposure to tobacco smoke outside home	8.4	11.2	27.4	-1.3	-5.2	-1.8	-5.1	-2.7	-0.6	-3.9	-3.0
Comparative body size at age 10	1.0	2.8	7.9	1.3	-2.0	-2.8	-1.4	-1.0	-1.5	-0.4	-1.8
Number of full brothers	0.2	0.3	0.8	-0.3	-0.7	-0.3	-0.9	0.0	0.4	-0.8	0.5
Worry too long after embarrassment	3.1	5.2	13.3	-1.9	-3.7	0.2	-3.5	-2.0	0.5	-2.8	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	4.5	5.9	11.8	-1.9	-3.4	1.5	-3.4	-2.6	-0.1	-3.0	-1.5
Wheeze or whistling in the chest in last year	0.5	1.0	1.6	-1.2	-1.2	1.2	-0.7	-0.4	-1.0	-0.9	-0.9
Number of children fathered	0.6	0.7	1.9	1.4	-0.2	-1.1	-0.4	0.3	1.3	0.1	1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.4	-0.0	0.3	0.6	0.6	0.3	-0.8	1.2	-0.7
Age at first live birth	2.2	4.0	10.8	0.4	2.9	2.3	3.3	1.9	0.7	1.7	-0.3
Pulse wave peak to peak time	0.5	0.6	1.8	0.4	0.9	1.3	0.9	0.2	-1.0	-0.2	0.1
Health satisfaction	1.4	1.8	5.3	1.6	0.3	-1.1	0.9	0.5	-2.3	0.7	-1.9
Shortness of breath walking on level ground	1.6	2.0	7.6	1.3	-0.1	-1.3	0.6	-0.7	-1.9	0.3	-2.7
Qualifications: College or University degree	2.6	8.2	19.4	0.3	4.1	3.4	4.4	2.3	-0.5	3.3	1.0
Eye problems/disorders: None of the above	0.1	0.1	0.4	-0.5	-0.1	-0.4	-0.2	-0.6	0.3	-0.3	0.1
Mouth/teeth dental problems: Loose teeth	0.9	1.1	3.0	0.5	-1.2	-0.9	-0.9	-0.5	-1.3	-0.8	-1.7
Emphysema/chronic bronchitis	0.5	0.6	1.6	1.3	0.8	-0.2	1.3	0.1	-0.7	0.4	-0.0
Medication for pain relief, constipation, heartburn	2.1	3.6	7.3	0.6	2.5	1.2	2.7	2.5	-0.8	2.4	0.6
Neck or shoulder pain in last month	0.3	0.5	1.2	1.0	-0.3	-0.0	0.2	-0.4	-0.9	0.7	-1.1
Medication: Blood pressure	1.2	2.1	5.5	1.8	0.3	-1.2	1.1	-0.2	-1.6	1.6	-2.3
Angina (self-reported)	2.0	2.7	9.0	3.0	0.5	-0.4	1.3	1.1	-1.5	1.2	-2.3
Migraine (self-reported)	0.8	1.0	2.2	1.0	-1.4	-0.1	-1.5	-0.0	-0.6	0.8	-1.3
Medication: Ibuprofen	1.0	1.2	2.6	1.0	-0.1	0.4	-0.6	-1.0	1.5	-1.6	1.4
Medication: Allopurinol	0.5	0.7	2.4	1.2	-0.2	-1.5	0.3	-0.3	-0.1	-0.9	-0.9
Medication: Omeprazole	0.9	1.0	6.5	-0.7	0.5	2.6	0.1	0.3	0.1	-0.6	0.8
Medication: Seretide 50 evohaler	1.0	1.2	4.2	0.1	0.9	2.0	0.5	1.4	-0.3	-0.0	1.4
Mean time to correctly identify matches	0.2	0.4	1.2	1.1	0.3	-0.5	0.2	-0.3	-0.2	1.0	-0.5
Heart disease (mother)	0.7	0.9	2.3	1.2	0.3	-1.5	0.3	0.8	-0.7	1.3	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.2	-0.7	0.4	0.7	0.1	-0.4	0.6	-1.5	0.3
Whole body fat mass	0.5	2.3	13.6	1.3	-0.7	-3.7	-0.6	-0.7	0.1	0.1	-1.3
Leg fat mass (right)	0.7	2.9	15.3	0.7	-1.3	-3.9	-1.3	-1.3	0.6	-0.6	-1.3
Arm predicted mass (right)	0.4	2.3	8.2	1.1	1.6	-2.9	1.4	0.2	1.7	1.2	0.1
Pulse rate, automated reading	0.4	1.2	5.3	0.3	0.1	-1.3	0.7	-0.4	-1.3	0.5	-2.3
Alcohol intake frequency.	0.9	2.0	5.7	-1.6	-2.0	0.2	-2.4	-0.7	0.6	-1.4	0.6
Comparative height size at age 10	0.8	4.5	11.4	0.7	2.9	-0.6	1.9	1.5	3.4	1.0	3.0
Number of full sisters	2.6	3.1	8.9	-2.0	-1.2	-0.3	-1.9	-2.1	1.5	-3.0	-0.0
Suffer from ‘nerves’	1.0	1.5	3.6	-1.4	-1.2	-0.1	-0.5	-1.3	-1.1	-1.3	-1.9
Overall health rating	2.0	4.3	13.0	0.9	-1.7	-2.2	-0.9	-1.4	-2.7	-1.7	-3.6
Chest pain or discomfort	0.6	0.8	2.2	0.8	-0.3	-1.4	0.4	-0.5	-1.1	-0.4	-1.5
Had major operations	0.4	0.4	1.2	-0.9	-1.1	-0.4	-1.0	-0.3	-0.0	-0.4	0.3
Age at last live birth	1.3	1.9	4.6	0.7	1.7	1.8	2.2	1.2	0.3	1.1	-1.0
Family relationship satisfaction	1.0	1.2	5.6	-0.7	-0.7	0.1	-0.6	-0.8	-1.3	-2.4	-0.4
Leg pain on walking	0.6	0.8	3.7	1.1	-0.1	-0.5	-0.3	0.1	-1.9	0.5	-0.7
Qualifications: NVQ or HND or HNC or equivalent	2.9	3.5	6.0	-1.2	-2.4	-1.7	-2.4	-2.5	1.0	-2.4	-0.2
Commuting to job workplace: Car/motor vehicle	2.7	3.1	6.6	2.4	2.1	0.1	2.6	2.1	-0.2	1.5	1.2
Illness, injury, bereavement, stress in last 2 years	4.8	5.8	19.0	1.9	4.4	-0.4	3.7	1.8	0.7	2.1	1.4
Medication: Aspirin	0.9	1.2	4.3	-0.9	-2.1	-0.4	-1.3	-0.4	-1.3	0.5	-0.9
Supplements: Vitamin C	0.7	0.8	1.7	-0.5	-1.0	-1.3	-1.3	-0.9	0.7	-0.9	0.4
Knee pain experienced in last month	1.1	1.6	7.2	1.3	0.6	-2.7	0.4	-0.8	-0.8	0.1	-1.5
Hypertension (Self-reported)	0.6	1.8	7.2	1.6	0.5	-0.9	0.6	1.2	-0.3	2.7	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	4.3	-0.2	1.4	0.7	1.2	1.0	-0.6	2.1	0.6
Illnesses of father: Heart disease	0.3	0.4	1.3	0.5	0.4	1.1	0.5	-0.2	-1.1	-0.2	-0.3
Illnesses of siblings: Diabetes	0.7	0.9	2.2	0.6	-1.3	-1.5	-0.8	-0.7	-0.7	0.4	-1.0
Smoking status: Previous	2.5	3.8	7.4	-0.6	-2.5	-0.8	-2.7	-2.3	0.7	-2.6	-1.8
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.8	0.2	-0.0	-0.6	-0.2	-1.0	-0.9	-1.3	-0.8
Whole body fat-free mass	0.3	1.5	6.8	0.5	1.1	-2.6	0.9	-0.5	1.6	0.4	-0.1
Leg fat-free mass (right)	0.2	0.9	4.6	0.4	0.4	-2.1	0.2	-0.7	1.5	0.0	0.0
Arm fat percentage (left)	0.6	2.5	9.4	1.3	-1.7	-3.1	-1.4	-0.9	-0.7	-0.5	-1.5
Average weekly red wine intake	3.1	4.6	7.9	2.0	2.8	1.8	2.8	2.3	-0.6	2.8	1.2
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.2	0.1	1.3	-0.8	1.5	0.0	-0.7	-0.0	-0.0
Mood swings	4.2	7.5	19.5	-1.5	-4.4	-1.1	-4.4	-1.8	0.2	-3.3	-1.9
Loneliness, isolation	1.7	2.3	5.0	-0.9	-2.2	0.2	-2.2	-1.0	-0.4	-2.1	-1.6
Long-standing illness, disability or infirmity	2.3	3.6	6.3	-1.3	-2.4	-1.6	-2.1	-1.4	-1.8	-1.6	-2.5
Ever had bowel cancer screening	2.4	2.8	8.4	1.6	2.9	0.6	2.8	0.1	0.2	1.3	1.2
Diabetes diagnosed by doctor	1.3	2.2	6.8	-1.2	-2.6	-0.6	-2.4	-0.8	0.2	-1.1	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.6	0.0	-0.6	0.1	-0.2	-1.2	0.8	-1.3	0.3
Friendships satisfaction	1.2	1.5	4.5	0.9	1.9	-0.2	2.1	1.6	-0.3	0.7	0.1
Qualifications: nursing, teaching	3.4	5.3	8.9	1.8	3.0	2.6	2.7	3.0	0.2	2.4	1.3
Commuting to job workplace: Walk	0.8	0.9	2.6	-0.3	-0.9	-0.6	-0.5	-0.2	-1.6	0.6	-1.5
Eye problems/disorders: Cataract	1.0	1.1	3.2	0.7	0.9	0.9	1.0	1.8	-0.1	1.3	0.9
Mouth/teeth dental problems: Mouth ulcers	1.5	2.4	5.8	1.6	1.9	-0.8	2.3	0.7	0.6	2.4	0.1
Medication for cholesterol	1.6	2.4	5.6	-2.4	-1.3	1.0	-1.6	-2.1	-1.0	-1.5	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.7	0.3	0.5	-1.3	0.1	-0.6	1.2	-0.4	-0.1
Back pain experienced in last month	1.4	2.0	4.2	1.9	1.5	-0.4	2.0	0.7	-1.0	1.5	-1.4
Mineral and other dietary supplements	0.8	1.1	3.3	0.4	-0.9	-1.5	-0.5	-0.4	-1.4	-0.3	-1.8
Breast cancer (self-reported)	0.5	0.6	1.6	-0.2	-0.3	-0.4	0.3	-0.8	-0.9	-1.0	-1.3
Asthma (self-reported)	1.4	2.7	14.6	-1.8	0.3	3.8	0.5	0.9	-1.6	0.3	0.6
Osteoporosis (self-reported)	0.7	0.8	2.9	-0.5	-1.7	-0.4	-0.6	-0.7	-1.1	-0.8	-0.9
Osteoarthritis (self-reported)	0.4	0.5	1.9	-0.4	0.9	0.3	-0.2	-0.0	0.9	0.3	1.4
Medication: Aspirin	0.8	1.1	3.2	-0.4	-1.8	-0.1	-1.2	-0.3	-1.4	0.8	-1.0
Medication: Gliclazide	0.7	0.8	3.0	-0.3	-0.0	1.7	-0.3	-0.6	0.1	-1.6	0.4
Illnesses of father: None of the above (group 1)	0.2	0.3	1.6	-0.5	0.1	-1.3	0.4	-0.3	0.4	0.3	0.1
Smoking status: Current	6.4	10.1	24.4	-1.6	-4.2	-2.3	-4.9	-3.1	0.8	-4.3	-1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	2.5	0.2	0.2	1.1	0.0	0.4	0.1	-1.2	1.6
Whole body water mass	0.2	1.4	6.0	0.6	1.2	-2.5	1.0	-0.4	1.5	0.5	-0.1
Leg predicted mass (right)	0.2	0.9	4.4	0.4	0.4	-2.1	0.2	-0.7	1.4	0.1	0.0
Arm fat mass (left)	0.6	2.4	12.9	1.6	-0.8	-3.6	-0.7	-0.9	-0.1	-0.2	-1.3
Number of self-reported non-cancer illnesses	0.4	0.6	2.4	0.7	0.5	-0.1	0.6	1.2	-0.0	1.5	0.1
Average weekly champagne plus white wine intake	2.1	2.9	13.0	-0.0	1.6	1.1	0.7	0.3	3.6	0.2	2.5
Miserableness	6.6	11.4	23.7	-2.0	-4.9	-1.9	-4.3	-2.8	-2.0	-3.3	-4.4
Guilty feelings	2.6	4.0	12.4	-0.4	-3.5	1.0	-3.2	-1.0	0.1	-2.6	-0.4
Wears glasses or contact lenses	2.5	2.9	6.9	0.9	2.1	1.2	2.1	1.9	-0.5	2.6	1.1
Ever taken oral contraceptive pill	0.5	0.6	1.6	-0.1	1.3	0.7	0.8	-0.4	-0.4	-1.1	0.7
Hearing aid user	2.6	2.9	6.6	1.2	2.1	-0.1	2.6	0.7	-2.5	2.0	-0.5
Mother’s age at death	1.5	1.8	4.1	-0.7	1.8	2.0	1.0	1.1	0.8	0.4	1.9
Financial situation satisfaction	2.2	2.8	4.5	-1.1	-1.2	-1.7	-1.1	-1.9	-2.0	-1.9	-2.1
Tinnitus: Yes, now most or all of the time	1.4	1.7	11.0	-0.6	0.8	3.3	0.6	0.3	-1.0	-0.1	0.1
Commuting to job workplace: Public transport	2.6	3.1	6.7	-2.6	-2.3	-0.2	-2.5	-2.1	0.6	-1.0	-1.2
Eye problems/disorders: Glaucoma	1.3	1.5	5.7	-0.7	-2.1	-0.2	-2.4	-0.1	0.8	-0.6	0.1
Medication: Blood pressure	0.4	0.8	1.9	0.7	0.4	0.2	0.6	1.4	1.1	1.4	0.3
Pain type(s) experienced in last month: Hip pain	1.7	2.2	5.6	-1.5	-1.0	0.4	-1.4	-2.1	-0.1	-2.4	-1.3
Supplements: Fish oil (including cod liver oil)	0.9	1.1	5.1	-0.5	0.7	1.2	0.4	0.4	1.0	0.6	2.3
High cholesterol (Self-reported)	2.2	3.9	8.0	2.8	2.2	-0.4	2.4	2.2	-1.4	2.4	-0.5
Medication: Bendroflumethiazide	1.4	2.2	4.8	2.2	1.2	-1.7	1.4	0.2	0.2	2.0	-1.5
Medication: Paracetamol	1.9	2.9	5.1	-0.3	-2.1	-1.0	-2.0	-2.3	1.2	-2.2	-1.6
Medication: Lisinopril	0.4	0.5	1.0	0.6	-1.0	-0.4	-0.5	-0.1	0.6	-0.8	-1.0
Medication: Atorvastatin	0.8	0.9	3.4	0.3	-0.1	-0.1	0.2	-0.7	-1.9	-0.0	-1.8
Illnesses of father: High blood pressure	0.7	0.9	2.9	0.9	1.7	0.4	1.3	1.1	-0.4	0.2	-0.1
Alcohol drinker status: Never	1.7	2.1	6.2	1.3	2.5	-0.4	2.0	0.9	-0.1	1.6	1.1
Ever smoked	10.6	18.7	43.0	-2.1	-6.1	-1.3	-6.6	-4.8	1.0	-5.5	-2.7
Basal metabolic rate	0.3	1.5	8.5	0.7	0.7	-2.9	0.5	-0.6	1.3	0.3	-0.5
Leg fat percentage (left)	0.9	3.2	14.5	1.2	-1.8	-3.8	-1.4	-0.8	-0.8	-0.1	-1.8
Arm fat-free mass (left)	0.3	1.5	6.6	0.9	1.1	-2.6	0.9	-0.2	1.5	0.8	-0.2
Number of operations (self-reported)	0.6	0.9	2.2	0.8	0.3	-1.5	0.0	-0.5	1.3	-0.3	1.4
Average weekly beer plus cider intake	4.5	6.6	12.5	1.5	-3.5	-3.3	-3.0	-2.2	-0.9	-3.1	-1.8
Irritability	1.1	1.8	4.1	-0.9	-2.0	1.3	-1.4	-0.5	-1.0	-2.0	-0.7
Risk taking	1.3	1.9	4.4	-1.6	-0.3	-0.7	-1.1	-1.2	2.1	-2.1	0.3
Ever had prostate specific antigen (PSA) test	2.2	2.5	6.4	1.6	2.0	-0.7	2.5	1.1	-0.8	1.9	-1.1
Fractured/broken bones in last 5 years	4.5	5.8	13.4	-2.4	-3.7	0.2	-3.6	-2.1	-0.0	-2.9	-1.2
Age started oral contraceptive pill	2.7	3.4	6.7	-0.1	2.5	1.6	2.4	1.7	0.9	2.6	1.5
Diastolic blood pressure, automated reading	0.2	0.7	1.5	0.9	1.1	0.2	0.7	0.9	0.5	1.2	-0.9
Ever depressed for a whole week	1.1	1.4	5.5	-2.3	-0.6	0.5	-1.0	-0.5	-0.1	-1.8	-0.8
Unable to work because of sickness or disability	2.2	2.9	6.2	-0.3	-2.5	-0.6	-2.3	-1.3	-0.9	-1.9	-2.1
Commuting to job workplace: Cycle	0.8	1.0	2.2	-0.9	1.4	0.8	1.5	0.2	-0.6	0.7	-1.0
Myopia	0.6	0.9	3.2	1.2	0.5	0.6	0.2	1.0	1.2	-0.2	1.8
Vascular/heart problems diagnosed by doctor	1.2	3.3	8.9	-2.3	0.1	1.4	-0.4	-1.7	1.4	-3.0	2.3
Cholesterol lowering medication	1.9	2.8	6.3	2.5	1.8	0.6	1.7	2.4	0.3	1.8	0.9
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	4.9	-0.6	0.4	2.2	0.2	-0.5	0.1	-1.0	0.4
Pain experienced in last month	0.5	0.8	1.5	-0.7	0.4	1.2	0.4	1.2	-0.1	0.9	1.2
Supplements: Calcium	1.2	1.3	4.6	-0.5	0.1	1.0	-0.1	1.4	1.6	0.3	2.1
Basal cell carcinoma (self-reported)	0.9	1.0	2.8	1.2	1.2	-0.7	1.7	-0.1	-0.9	0.6	-0.9
Heart attack/myocardial infarction (self-reported)	1.8	2.3	9.7	0.8	-1.0	-0.6	0.3	0.8	-2.1	1.3	-3.1
Deep venous thrombosis (DVT) (self-reported)	0.3	0.3	1.6	0.0	-0.6	-0.2	-1.3	0.5	0.6	-0.1	0.3
Heart disease (siblings)	0.6	0.7	1.3	1.1	-0.8	-0.9	-0.7	-0.5	1.0	-0.9	0.2
Alcohol drinker status: Previous	2.7	3.1	7.3	-1.5	-2.7	0.6	-2.6	-0.9	0.9	-2.5	0.4
Pack years of smoking	1.0	1.5	3.6	-0.3	-1.7	-1.2	-1.9	-1.1	1.2	-1.3	0.2
Impedance of whole body	0.2	0.9	6.1	-0.1	0.1	2.5	-0.1	0.7	-0.7	-0.5	0.4
Leg fat mass (left)	0.8	3.1	16.4	0.8	-1.4	-4.1	-1.4	-1.3	0.5	-0.5	-1.3
Arm predicted mass (left)	0.3	1.6	8.6	0.6	0.8	-2.9	0.7	-0.4	1.5	0.7	-0.3