Best TWAS P=4.33e-08 · Best GWAS P=4.95e-08 conditioned to 0.00279
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | GAPVD1 | 0.11 | 0.16 | enet | 19 | 0.16 | 6.4e-13 | 5.4 | 5.4 | 5.2e-08 | 0.94 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Brain Cerebellum | PRPS1P2 | 0.09 | 0.08 | enet | 16 | 0.04 | 2.8e-02 | 5.2 | -5.4 | 7.3e-08 | -0.78 | 0.06 | 0.72 | FALSE |
| 3 | GTEx | Muscle Skeletal | GAPVD1 | 0.13 | 0.10 | lasso | 3 | 0.09 | 4.7e-09 | 5.2 | -5.2 | 1.8e-07 | -0.96 | 0.03 | 0.97 | FALSE |
| 4 | GTEx | Spleen | PRPS1P2 | 0.18 | 0.02 | lasso | 4 | 0.04 | 3.9e-02 | -4.6 | -5.5 | 4.3e-08 | -0.53 | 0.10 | 0.15 | TRUE |
| 5 | GTEx | Thyroid | GAPVD1 | 0.05 | 0.05 | enet | 13 | 0.01 | 6.6e-02 | 5.2 | 5.3 | 1.1e-07 | 0.95 | 0.03 | 0.97 | FALSE |