[Hub]/) : Traits : Ever smoked : ← →

chr6:110,588,546-112,501,537

Best TWAS P=5.11e-12 · Best GWAS P=1.59e-13 conditioned to 0.00369

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex REV3L 0.15 0.10 lasso 5 0.14 9.8e-17 6.3 5.6 2.0e-08 0.73 0.73 0.27 FALSE
2 GTEx Adipose Subcutaneous RP5-1112D6.4 0.08 0.03 lasso 4 0.03 2.1e-03 5.6 6.2 4.3e-10 0.83 0.04 0.95 FALSE
3 GTEx Artery Aorta RP5-1112D6.4 0.15 0.01 lasso 7 0.02 3.5e-02 6.5 5.5 3.1e-08 0.72 0.06 0.74 FALSE
4 GTEx Brain Cerebellum REV3L 0.31 0.04 lasso 11 0.12 2.4e-04 7.3 6.9 5.1e-12 0.84 0.02 0.91 TRUE
5 GTEx Brain Hypothalamus GTF3C6 0.32 0.04 lasso 4 0.08 6.8e-03 7.3 -6.7 1.6e-11 -0.90 0.02 0.84 FALSE
6 GTEx Cells Transformed fibroblasts RP5-1112D6.4 0.15 0.06 lasso 2 0.06 4.0e-05 5.6 6.0 2.1e-09 0.80 0.11 0.85 FALSE
7 GTEx Colon Transverse RP5-1112D6.4 0.11 0.10 lasso 4 0.06 7.1e-04 6.5 6.7 2.1e-11 0.80 0.32 0.22 FALSE
8 GTEx Pituitary RP5-1112D6.4 0.23 0.16 lasso 4 0.13 4.4e-04 4.9 5.7 1.0e-08 0.78 0.08 0.62 FALSE
9 ROSMAP Brain Pre-frontal Cortex REV3L 0.16 0.16 bslmm 468 0.18 1.9e-22 6.5 5.4 6.5e-08 0.72 0.38 0.62 FALSE