TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Pack years adult smoking proportion
:
←
→
chr14:103,398,706-104,866,687
Best TWAS P=6.66e-08 · Best GWAS P=2.08e-07 conditioned to 0.633
103.4M
103.6M
103.8M
104M
104.2M
104.4M
104.6M
104.8M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adrenal Gland
KLC1
0.15
0.03
lasso
3
0.06
4.6e-03
5.1
5.4
6.7e-08
0.93
0.02
0.86
TRUE
5
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
XRCC3
0.03
0.04
enet
3
0.04
6.1e-05
5.1
5.2
2.4e-07
0.98
0.00
1.00
FALSE
2
GTEx
Esophagus Mucosa
XRCC3
0.12
0.15
lasso
2
0.13
4.4e-09
5.1
5.2
2.5e-07
1.00
0.00
1.00
FALSE
3
GTEx
Prostate
RP11-73M18.8
0.15
0.29
lasso
1
0.25
5.2e-07
5.1
5.1
2.6e-07
1.00
0.00
0.99
FALSE
4
GTEx
Testis
KLC1
0.17
0.17
lasso
2
0.15
4.4e-07
5.1
5.1
2.9e-07
0.97
0.00
0.99
FALSE