Best TWAS P=6.66e-08 · Best GWAS P=2.08e-07 conditioned to 0.633
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | KLC1 | 0.15 | 0.03 | lasso | 3 | 0.06 | 4.6e-03 | 5.1 | 5.4 | 6.7e-08 | 0.93 | 0.02 | 0.86 | TRUE |
| 2 | GTEx | Esophagus Mucosa | XRCC3 | 0.12 | 0.15 | lasso | 2 | 0.13 | 4.4e-09 | 5.1 | 5.2 | 2.5e-07 | 1.00 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Prostate | RP11-73M18.8 | 0.15 | 0.29 | lasso | 1 | 0.25 | 5.2e-07 | 5.1 | 5.1 | 2.6e-07 | 1.00 | 0.00 | 0.99 | FALSE |
| 4 | GTEx | Testis | KLC1 | 0.17 | 0.17 | lasso | 2 | 0.15 | 4.4e-07 | 5.1 | 5.1 | 2.9e-07 | 0.97 | 0.00 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | XRCC3 | 0.03 | 0.04 | enet | 3 | 0.04 | 6.1e-05 | 5.1 | 5.2 | 2.4e-07 | 0.98 | 0.00 | 1.00 | FALSE |