TWAS
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About
Usage
Models
Genes
Traits
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Traits
:
Pack years adult smoking proportion
:
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chr17:35,152,143-36,441,093
Best TWAS P=1.85e-07 · Best GWAS P=1.13e-06 conditioned to 0.439
35.2M
35.4M
35.6M
35.8M
36M
36.2M
36.4M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Nerve Tibial
DUSP14
0.25
0.21
lasso
4
0.27
4.4e-19
4.7
-5.2
1.9e-07
-0.86
0
0.99
TRUE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
SYNRG
0.01
0.00
blup
57
0.00
1.2e-01
4.7
5.2
2.6e-07
0.69
0
0.40
FALSE