TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Pack years adult smoking proportion
:
←
chr19:41,034,912-41,537,868
Best TWAS P=5.6e-09 · Best GWAS P=2.54e-09 conditioned to 5.52e-05
41.1M
41.2M
41.3M
41.4M
41.5M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Thyroid Carcinoma
RAB4B
0.14
0.03
blup
58
0.06
6.5e-07
-3.8
-5.8
5.6e-09
-0.38
0.79
0.17
TRUE
1
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
RAB4B
0.10
0.07
lasso
5
0.08
4.2e-09
3.5
-5.3
1.2e-07
-0.72
0.26
0.74
FALSE