Best TWAS P=5.6e-09 · Best GWAS P=2.54e-09 conditioned to 5.52e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | RAB4B | 0.10 | 0.07 | lasso | 5 | 0.08 | 4.2e-09 | 3.5 | -5.3 | 1.2e-07 | -0.72 | 0.26 | 0.74 | FALSE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | RAB4B | 0.14 | 0.03 | blup | 58 | 0.06 | 6.5e-07 | -3.8 | -5.8 | 5.6e-09 | -0.38 | 0.79 | 0.17 | TRUE |