Best TWAS P=5.23e-08 · Best GWAS P=3.33e-07 conditioned to 0.118
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | FAM86B3P | 0.19 | 0.14 | lasso | 5 | 0.16 | 1.8e-05 | -4.7 | 5.3 | 1.3e-07 | -0.88 | 0.02 | 0.97 | FALSE |
| 2 | GTEx | Brain Cortex | FAM86B3P | 0.14 | 0.05 | enet | 9 | 0.07 | 5.1e-03 | -4.3 | 5.1 | 2.6e-07 | -0.81 | 0.04 | 0.75 | FALSE |
| 3 | GTEx | Brain Frontal Cortex BA9 | FAM86B3P | 0.16 | 0.13 | enet | 27 | 0.10 | 1.1e-03 | -3.9 | 5.4 | 5.2e-08 | -0.75 | 0.05 | 0.84 | TRUE |
| 4 | GTEx | Cells Transformed fibroblasts | FAM86B3P | 0.23 | 0.33 | lasso | 11 | 0.38 | 8.4e-30 | -4.9 | -5.3 | 1.1e-07 | 0.83 | 0.01 | 0.98 | FALSE |