Best TWAS P=8.93e-09 · Best GWAS P=1.35e-07 conditioned to 0.193
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | AF131215.9 | 0.18 | 0.16 | lasso | 10 | 0.18 | 3.5e-07 | -4.6 | -5.3 | 1.2e-07 | 0.94 | 0.07 | 0.92 | FALSE |
| 2 | GTEx | Colon Sigmoid | AF131215.2 | 0.10 | 0.00 | enet | 7 | 0.02 | 5.0e-02 | -4.3 | -5.2 | 2.4e-07 | 0.81 | 0.13 | 0.47 | FALSE |
| 3 | GTEx | Prostate | AF131215.2 | 0.18 | 0.02 | lasso | 6 | 0.02 | 9.6e-02 | -5.2 | -5.7 | 8.9e-09 | 0.77 | 0.07 | 0.51 | TRUE |
| 4 | GTEx | Skin Sun Exposed Lower leg | AF131215.9 | 0.19 | 0.17 | enet | 29 | 0.21 | 3.9e-17 | 4.4 | -5.5 | 4.6e-08 | 0.83 | 0.49 | 0.47 | FALSE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | FAM167A | 0.12 | 0.03 | bslmm | 620 | 0.08 | 1.3e-10 | -3.7 | 5.5 | 4.4e-08 | -0.69 | 0.10 | 0.89 | FALSE |