Hub : Traits :

Guilty feelings

101 significantly associated models · 32 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 2 22911727 24924438 2 2 7.1e-14 3.5e-13 1.0000 100 KLHL29 UBXN2A
2 6 104706579 106230491 1 1 1.2e-07 1.8e-07 0.2070 94 LIN28B
3 8 8092025 8794801 1 1 5.2e-08 3.3e-07 0.1180 91 FAM86B3P
4 8 10265712 11891593 3 1 8.9e-09 1.4e-07 0.1930 94 AF131215.2
5 11 46917983 48303325 2 1 1.6e-07 1.1e-07 0.1890 94 C1QTNF4
6 11 56742853 58178587 3 1 5.3e-09 1.3e-07 0.1910 94 MED19
7 11 112135760 113969669 5 3 3.0e-09 2.4e-09 0.1110 93 ANKK1 DRD2 TTC12
8 14 74424938 76089054 4 1 1.8e-09 2.9e-09 0.0036 76 AREL1
9 15 77207277 78806023 1 1 1.6e-07 2.0e-07 1.0000 100 LINGO1
10 17 42774693 43913030 7 1 9.3e-09 1.8e-07 0.0838 89 PLEKHM1
11 22 39229593 40615276 1 1 1.0e-07 2.8e-07 0.3330 96 ATF4

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Bipolar Disorder or Schizophrenia 3.08 4 0 0.0 -0.33 6.7e-01 DRD2 FAM86B3P LIN28B TTC12
Depressed Affect (Nagel 2018) 12.57 10 6 13.3 0.96 1.6e-05 ANKK1 AREL1 C1QTNF4 DRD2 LIN28B LINGO1 MED19 PLEKHM1 TTC12 UBXN2A
Depression (Nagel 2018) 6.94 6 0 0.0 1.00 8.4e-06 ANKK1 DRD2 KLHL29 MED19 PLEKHM1 UBXN2A
Intelligence (Savage-Jansen 2018) 2.17 2 0 0.0 0.00 1.0e+00 ATF4 PLEKHM1
Neuroticism (Nagel 2018) 14.86 10 8 17.8 0.95 3.2e-05 ANKK1 AREL1 C1QTNF4 DRD2 LIN28B LINGO1 MED19 PLEKHM1 TTC12 UBXN2A
Schizophrenia (2018) 3.75 5 0 0.0 0.14 8.2e-01 ANKK1 DRD2 FAM86B3P LIN28B TTC12
Worry (Nagel 2018) 8.64 7 4 8.9 0.98 1.2e-04 ANKK1 AREL1 C1QTNF4 DRD2 LINGO1 PLEKHM1 TTC12
Alzheimer’s Disease (including proxy) 1.50 1 0 0.0 0.00 1.0e+00 C1QTNF4
Major Depression (MDD) 3.78 1 0 0.0 0.00 1.0e+00 AREL1
Reaction Time 1.20 1 0 0.0 0.00 1.0e+00 UBXN2A
Verbal and Numeric Reasoning (VNR) 2.80 3 0 0.0 0.00 1.0e+00 ATF4 C1QTNF4 PLEKHM1
Breast Cancer 1.47 1 1 2.2 0.00 1.0e+00 PLEKHM1
Ovarian Cancer 3.16 1 1 2.2 0.00 1.0e+00 PLEKHM1
Body Mass Index (BMI) (2010) 3.65 1 1 2.2 0.00 1.0e+00 C1QTNF4
Fasting Glucose 1.60 1 0 0.0 0.00 1.0e+00 C1QTNF4
HbA1C 1.60 1 0 0.0 0.00 1.0e+00 UBXN2A
Lupus 3.19 2 0 0.0 0.00 1.0e+00 AF131215.2 FAM86B3P
Neuroticism (2016) 13.51 8 3 6.7 0.97 6.7e-05 AF131215.2 ANKK1 AREL1 C1QTNF4 DRD2 FAM86B3P LINGO1 PLEKHM1
Primary Biliary Cirrhosis 1.86 1 0 0.0 0.00 1.0e+00 PLEKHM1
Schizophrenia (2014) 4.56 5 0 0.0 -0.25 6.8e-01 AREL1 DRD2 FAM86B3P LIN28B TTC12
Triglycerides 1.41 1 0 0.0 0.00 1.0e+00 AF131215.2
Blood Eosinophil Count 1.76 1 1 2.2 0.00 1.0e+00 PLEKHM1
Blood Platelet Count 1.47 5 4 8.9 0.21 7.4e-01 AREL1 C1QTNF4 MED19 PLEKHM1 UBXN2A
Blood Red Count 4.63 6 2 4.4 0.64 1.7e-01 ATF4 C1QTNF4 DRD2 MED19 PLEKHM1 UBXN2A
Blood White Count 2.49 5 3 6.7 0.36 5.5e-01 C1QTNF4 KLHL29 LIN28B PLEKHM1 UBXN2A
Heel T-Score 1.94 4 2 4.4 -0.13 8.7e-01 AREL1 C1QTNF4 LIN28B PLEKHM1
BMI 2.65 4 1 2.2 0.27 7.3e-01 ANKK1 C1QTNF4 KLHL29 TTC12
Height 3.30 6 6 13.3 -0.81 5.0e-02 AREL1 C1QTNF4 KLHL29 LIN28B PLEKHM1 UBXN2A
Waist Hip Ratio (WHR) 2.42 4 1 2.2 0.95 5.4e-02 ANKK1 AREL1 PLEKHM1 UBXN2A
Systolic Blood Pressure 4.83 4 4 8.9 0.32 6.8e-01 AREL1 C1QTNF4 MED19 PLEKHM1
Smoking Status 1.89 2 0 0.0 0.00 1.0e+00 KLHL29 PLEKHM1
Cardiovascular Disease 1.75 3 0 0.0 0.00 1.0e+00 ANKK1 DRD2 TTC12
Hypothyroidism (self reported) 2.08 2 0 0.0 0.00 1.0e+00 AREL1 C1QTNF4
Respiratory disease 1.28 1 0 0.0 0.00 1.0e+00 MED19
Type 2 Diabetes (T2D) (2018) 1.10 1 0 0.0 0.00 1.0e+00 C1QTNF4
Lung FEV1/FVC ratio 1.30 2 1 2.2 0.00 1.0e+00 AREL1 PLEKHM1
Lung FVC 4.51 3 2 4.4 0.00 1.0e+00 LIN28B PLEKHM1 UBXN2A
Neuroticism 15.56 11 9 20.0 0.95 5.0e-06 ANKK1 AREL1 ATF4 C1QTNF4 DRD2 LIN28B LINGO1 MED19 PLEKHM1 TTC12 UBXN2A
Chronotype (morning person) 2.00 1 0 0.0 0.00 1.0e+00 UBXN2A
Hair Pigment 0.11 2 0 0.0 0.00 1.0e+00 KLHL29 PLEKHM1
Tanning 0.40 2 0 0.0 0.00 1.0e+00 AREL1 C1QTNF4
Hand grip strength (left) 5.46 6 3 6.7 -0.51 3.1e-01 AREL1 C1QTNF4 LIN28B LINGO1 PLEKHM1 UBXN2A
Number of treatments/medications taken 4.14 2 1 2.2 0.00 1.0e+00 AREL1 LIN28B
Sensitivity / hurt feelings 11.97 7 3 6.7 0.95 1.0e-03 AF131215.2 ANKK1 DRD2 FAM86B3P MED19 PLEKHM1 TTC12
Frequency of depressed mood in last 2 weeks 9.34 9 0 0.0 1.00 1.1e-08 AF131215.2 ANKK1 C1QTNF4 DRD2 FAM86B3P KLHL29 MED19 PLEKHM1 UBXN2A
Hearing difficulty/problems: Yes 2.33 1 0 0.0 0.00 1.0e+00 LIN28B
Relative age of first facial hair 6.96 2 2 4.4 0.00 1.0e+00 LIN28B PLEKHM1
Other serious medical condition/disability diagnosed by doctor 2.89 1 0 0.0 0.00 1.0e+00 TTC12
Systolic blood pressure, automated reading 5.11 6 4 8.9 -0.56 2.5e-01 AF131215.2 AREL1 C1QTNF4 FAM86B3P MED19 PLEKHM1
Vitamin and mineral supplements 1.80 1 0 0.0 0.00 1.0e+00 PLEKHM1
Medication: Metformin 2.38 1 1 2.2 0.00 1.0e+00 C1QTNF4
Impedance of leg (right) 4.26 7 4 8.9 0.58 1.7e-01 AF131215.2 AREL1 C1QTNF4 FAM86B3P LIN28B PLEKHM1 UBXN2A
Leg fat-free mass (left) 2.16 4 3 6.7 -0.99 5.3e-03 AF131215.2 FAM86B3P LIN28B UBXN2A
Trunk fat percentage 4.99 7 3 6.7 -0.05 9.2e-01 ANKK1 AREL1 C1QTNF4 LIN28B MED19 PLEKHM1 TTC12
Hand grip strength (right) 3.82 5 2 4.4 -0.45 4.4e-01 AREL1 C1QTNF4 LIN28B LINGO1 PLEKHM1
Current tobacco smoking 3.77 2 0 0.0 0.00 1.0e+00 C1QTNF4 UBXN2A
Fed-up feelings 12.36 10 6 13.3 0.97 2.1e-06 AF131215.2 ANKK1 AREL1 C1QTNF4 DRD2 FAM86B3P LINGO1 MED19 PLEKHM1 UBXN2A
Frequency of unenthusiasm / disinterest in last 2 weeks 7.80 6 0 0.0 0.99 4.4e-05 ANKK1 DRD2 KLHL29 MED19 TTC12 UBXN2A
Relative age voice broke 6.72 2 2 4.4 0.00 1.0e+00 LIN28B PLEKHM1
Taking other prescription medications 3.96 1 1 2.2 0.00 1.0e+00 AREL1
Age when periods started (menarche) 12.37 3 1 2.2 0.00 1.0e+00 C1QTNF4 LIN28B PLEKHM1
Heel bone mineral density (BMD) T-score, automated (left) 6.23 4 2 4.4 -0.74 2.6e-01 AF131215.2 FAM86B3P LIN28B PLEKHM1
High blood pressure 3.69 4 2 4.4 -0.66 3.4e-01 AF131215.2 C1QTNF4 FAM86B3P PLEKHM1
Medication: Levothyroxine sodium 2.89 1 1 2.2 0.00 1.0e+00 FAM86B3P
Sitting height 4.11 5 4 8.9 -0.72 1.7e-01 C1QTNF4 FAM86B3P KLHL29 PLEKHM1 UBXN2A
Body mass index (BMI) 4.45 4 3 6.7 -0.77 2.3e-01 AF131215.2 ANKK1 C1QTNF4 FAM86B3P
Impedance of leg (left) 4.38 8 4 8.9 0.55 1.6e-01 AF131215.2 AREL1 C1QTNF4 FAM86B3P LIN28B LINGO1 PLEKHM1 UBXN2A
Leg predicted mass (left) 2.17 4 3 6.7 -0.99 5.7e-03 AF131215.2 FAM86B3P LIN28B UBXN2A
Trunk fat mass 3.81 8 1 2.2 -0.30 4.7e-01 AF131215.2 ANKK1 AREL1 C1QTNF4 FAM86B3P LIN28B PLEKHM1 TTC12
Waist circumference 3.04 3 1 2.2 0.00 1.0e+00 ANKK1 C1QTNF4 TTC12
Past tobacco smoking 1.96 1 0 0.0 0.00 1.0e+00 PLEKHM1
Alcohol usually taken with meals 3.05 1 0 0.0 0.00 1.0e+00 MED19
Nervous feelings 11.01 8 4 8.9 0.97 8.2e-05 AF131215.2 ANKK1 AREL1 C1QTNF4 DRD2 FAM86B3P LINGO1 PLEKHM1
Frequency of tenseness / restlessness in last 2 weeks 8.13 5 1 2.2 0.98 4.4e-03 ANKK1 C1QTNF4 DRD2 KLHL29 PLEKHM1
Hearing difficulty/problems with background noise 5.25 3 0 0.0 0.00 1.0e+00 LIN28B PLEKHM1 TTC12
Hair/balding pattern: Pattern 2 2.52 1 1 2.2 0.00 1.0e+00 PLEKHM1
Forced vital capacity (FVC) 3.72 4 1 2.2 -0.89 1.1e-01 C1QTNF4 KLHL29 PLEKHM1 UBXN2A
Heel bone mineral density (BMD) T-score, automated (right) 6.63 4 2 4.4 -0.78 2.2e-01 AF131215.2 FAM86B3P LIN28B PLEKHM1
Ever unenthusiastic/disinterested for a whole week 3.16 1 0 0.0 0.00 1.0e+00 PLEKHM1
Financial difficulties in last 2 years 3.24 1 0 0.0 0.00 1.0e+00 DRD2
Mouth/teeth dental problems 2.02 1 0 0.0 0.00 1.0e+00 PLEKHM1
Fluid intelligence score 2.00 1 0 0.0 0.00 1.0e+00 PLEKHM1
Neuroticism score 21.65 13 11 24.4 0.96 3.6e-07 AF131215.2 ANKK1 AREL1 ATF4 C1QTNF4 DRD2 FAM86B3P KLHL29 LINGO1 MED19 PLEKHM1 TTC12 UBXN2A
Weight 2.23 6 2 4.4 -0.70 1.2e-01 AF131215.2 ANKK1 C1QTNF4 FAM86B3P LIN28B UBXN2A
Impedance of arm (right) 5.20 6 4 8.9 0.40 4.4e-01 AF131215.2 FAM86B3P LIN28B MED19 PLEKHM1 UBXN2A
Arm fat percentage (right) 5.17 7 2 4.4 -0.04 9.3e-01 AF131215.2 ANKK1 AREL1 C1QTNF4 FAM86B3P MED19 TTC12
Trunk fat-free mass 2.45 6 1 2.2 -0.97 1.8e-03 AF131215.2 AREL1 FAM86B3P KLHL29 LIN28B UBXN2A
Hip circumference 2.45 4 1 2.2 -0.69 3.1e-01 AF131215.2 ANKK1 C1QTNF4 FAM86B3P
Time employed in main current job 2.47 1 0 0.0 0.00 1.0e+00 PLEKHM1
Alcohol intake versus 10 years previously 2.30 1 0 0.0 0.00 1.0e+00 UBXN2A
Father's age at death 2.86 1 0 0.0 0.00 1.0e+00 AF131215.2
Worrier / anxious feelings 13.21 7 4 8.9 0.94 1.8e-03 AF131215.2 AREL1 DRD2 FAM86B3P LINGO1 MED19 PLEKHM1
Frequency of tiredness / lethargy in last 2 weeks 6.48 6 0 0.0 1.00 1.8e-05 ANKK1 DRD2 KLHL29 LINGO1 MED19 UBXN2A
Hair/balding pattern: Pattern 3 4.57 1 1 2.2 0.00 1.0e+00 PLEKHM1
Number of live births 1.46 1 0 0.0 0.00 1.0e+00 PLEKHM1
Forced expiratory volume in 1-second (FEV1) 4.65 6 1 2.2 -0.35 5.0e-01 AF131215.2 C1QTNF4 FAM86B3P KLHL29 PLEKHM1 UBXN2A
Qualifications: A levels/AS levels or equivalent 2.32 2 0 0.0 0.00 1.0e+00 AREL1 PLEKHM1
Serious illness, injury or assault of a close relative in last 2 years 1.93 1 0 0.0 0.00 1.0e+00 AF131215.2
Mouth/teeth dental problems: Dentures 1.79 2 0 0.0 0.00 1.0e+00 AF131215.2 FAM86B3P
Medication: Ibuprofen (e.g. Nurofen) 3.76 2 0 0.0 0.00 1.0e+00 PLEKHM1 UBXN2A
Depression (self-reported) 3.34 1 0 0.0 0.00 1.0e+00 LIN28B
Forced expiratory volume in 1-second (FEV1), Best measure 4.35 6 1 2.2 -0.34 5.1e-01 AF131215.2 C1QTNF4 FAM86B3P KLHL29 PLEKHM1 UBXN2A
Impedance of arm (left) 5.03 6 4 8.9 0.38 4.6e-01 AF131215.2 FAM86B3P LIN28B MED19 PLEKHM1 UBXN2A
Arm fat mass (right) 4.03 5 3 6.7 -0.34 5.8e-01 AF131215.2 ANKK1 C1QTNF4 FAM86B3P TTC12
Trunk predicted mass 2.47 6 1 2.2 -0.97 1.6e-03 AF131215.2 AREL1 FAM86B3P KLHL29 LIN28B UBXN2A
Standing height 3.51 8 4 8.9 -0.47 2.4e-01 AF131215.2 AREL1 C1QTNF4 FAM86B3P KLHL29 LIN28B PLEKHM1 UBXN2A
Tense / 'highly strung' 8.68 7 2 4.4 0.98 9.1e-05 AF131215.2 ANKK1 AREL1 DRD2 FAM86B3P PLEKHM1 TTC12
Seen doctor (GP) for nerves, anxiety, tension or depression 6.96 4 1 2.2 0.99 1.3e-02 ANKK1 AREL1 DRD2 TTC12
Hair/balding pattern: Pattern 4 6.73 1 1 2.2 0.00 1.0e+00 PLEKHM1
Peak expiratory flow (PEF) 4.31 4 1 2.2 -0.15 8.5e-01 AF131215.2 FAM86B3P PLEKHM1 UBXN2A
Medication: Paracetamol 5.07 3 1 2.2 0.00 1.0e+00 MED19 PLEKHM1 UBXN2A
Headache pain in last month 4.81 2 1 2.2 0.00 1.0e+00 MED19 PLEKHM1
Hypothyroidism/myxoedema (self-reported) 3.53 2 1 2.2 0.00 1.0e+00 AF131215.2 FAM86B3P
Birth weight 2.03 1 0 0.0 0.00 1.0e+00 UBXN2A
Forced vital capacity (FVC), Best measure 3.82 4 2 4.4 -0.86 1.4e-01 C1QTNF4 KLHL29 PLEKHM1 UBXN2A
Body fat percentage 4.88 6 2 4.4 -0.03 9.5e-01 ANKK1 AREL1 C1QTNF4 FAM86B3P PLEKHM1 TTC12
Leg fat percentage (right) 4.47 8 2 4.4 0.14 7.4e-01 AF131215.2 ANKK1 AREL1 C1QTNF4 FAM86B3P KLHL29 TTC12 UBXN2A
Arm fat-free mass (right) 2.03 3 2 4.4 0.00 1.0e+00 AF131215.2 FAM86B3P UBXN2A
Comparative body size at age 10 4.67 4 4 8.9 -0.61 3.9e-01 AF131215.2 C1QTNF4 FAM86B3P LIN28B
Number of full brothers 1.91 1 0 0.0 0.00 1.0e+00 PLEKHM1
Worry too long after embarrassment 11.70 9 5 11.1 0.98 1.5e-06 AF131215.2 ANKK1 ATF4 DRD2 FAM86B3P LINGO1 MED19 PLEKHM1 TTC12
Seen a psychiatrist for nerves, anxiety, tension or depression 4.15 1 0 0.0 0.00 1.0e+00 DRD2
Wheeze or whistling in the chest in last year 2.76 1 0 0.0 0.00 1.0e+00 TTC12
Age at first live birth 2.89 2 0 0.0 0.00 1.0e+00 AF131215.2 PLEKHM1
Health satisfaction 3.29 1 0 0.0 0.00 1.0e+00 DRD2
Qualifications: College or University degree 1.90 1 1 2.2 0.00 1.0e+00 PLEKHM1
Emphysema/chronic bronchitis 2.56 1 0 0.0 0.00 1.0e+00 FAM86B3P
Medication for pain relief, constipation, heartburn 4.16 4 1 2.2 -0.98 1.9e-02 AREL1 LIN28B PLEKHM1 UBXN2A
Medication: Blood pressure 2.38 2 0 0.0 0.00 1.0e+00 AF131215.2 C1QTNF4
Medication: Ibuprofen 3.07 2 0 0.0 0.00 1.0e+00 PLEKHM1 UBXN2A
Whole body fat mass 3.72 6 1 2.2 -0.09 8.6e-01 AF131215.2 ANKK1 AREL1 C1QTNF4 FAM86B3P TTC12
Leg fat mass (right) 3.71 6 3 6.7 -0.14 7.9e-01 AF131215.2 ANKK1 AREL1 C1QTNF4 FAM86B3P TTC12
Arm predicted mass (right) 2.05 3 3 6.7 0.00 1.0e+00 AF131215.2 FAM86B3P UBXN2A
Alcohol intake frequency. 5.18 6 2 4.4 0.37 4.7e-01 ATF4 C1QTNF4 DRD2 MED19 PLEKHM1 UBXN2A
Comparative height size at age 10 1.37 3 0 0.0 0.00 1.0e+00 KLHL29 PLEKHM1 UBXN2A
Suffer from 'nerves' 11.04 9 3 6.7 0.97 9.4e-06 AF131215.2 ANKK1 AREL1 C1QTNF4 DRD2 FAM86B3P LINGO1 PLEKHM1 TTC12
Overall health rating 3.53 4 0 0.0 0.60 4.0e-01 AF131215.2 ANKK1 DRD2 TTC12
Age at last live birth 2.80 1 0 0.0 0.00 1.0e+00 AF131215.2
Leg pain on walking 2.21 1 0 0.0 0.00 1.0e+00 PLEKHM1
Hypertension (Self-reported) 3.60 4 2 4.4 -0.66 3.4e-01 AF131215.2 C1QTNF4 FAM86B3P PLEKHM1
Forced expiratory volume in 1-second (FEV1), predicted 2.23 1 1 2.2 0.00 1.0e+00 LIN28B
Whole body fat-free mass 2.21 4 2 4.4 -1.00 4.3e-03 AF131215.2 FAM86B3P LIN28B UBXN2A
Leg fat-free mass (right) 2.17 4 3 6.7 -1.00 4.4e-03 AF131215.2 FAM86B3P LIN28B UBXN2A
Arm fat percentage (left) 5.32 7 3 6.7 -0.08 8.6e-01 AF131215.2 ANKK1 AREL1 C1QTNF4 FAM86B3P MED19 TTC12
Average weekly red wine intake 3.54 1 0 0.0 0.00 1.0e+00 MED19
Handedness (chirality/laterality): Left-handed 2.69 1 1 2.2 0.00 1.0e+00 PLEKHM1
Mood swings 12.78 9 5 11.1 0.98 1.5e-06 AF131215.2 ANKK1 AREL1 C1QTNF4 DRD2 FAM86B3P KLHL29 PLEKHM1 TTC12
Loneliness, isolation 7.09 2 1 2.2 0.00 1.0e+00 C1QTNF4 PLEKHM1
Long-standing illness, disability or infirmity 3.16 1 0 0.0 0.00 1.0e+00 LIN28B
Diabetes diagnosed by doctor 1.22 1 0 0.0 0.00 1.0e+00 C1QTNF4
Mouth/teeth dental problems: Mouth ulcers 2.84 1 1 2.2 0.00 1.0e+00 PLEKHM1
Medication for cholesterol 2.42 1 0 0.0 0.00 1.0e+00 PLEKHM1
Smoking status: Current 3.57 2 0 0.0 0.00 1.0e+00 AF131215.2 UBXN2A
Forced expiratory volume in 1-second (FEV1), predicted percentage 3.42 2 1 2.2 0.00 1.0e+00 AF131215.2 PLEKHM1
Whole body water mass 2.22 4 2 4.4 -0.99 5.2e-03 AF131215.2 FAM86B3P LIN28B UBXN2A
Leg predicted mass (right) 2.15 4 3 6.7 -1.00 4.6e-03 AF131215.2 FAM86B3P LIN28B UBXN2A
Arm fat mass (left) 4.03 5 3 6.7 -0.35 5.7e-01 AF131215.2 ANKK1 C1QTNF4 FAM86B3P TTC12
Number of self-reported non-cancer illnesses 2.46 1 0 0.0 0.00 1.0e+00 AREL1
Average weekly champagne plus white wine intake 1.65 1 0 0.0 0.00 1.0e+00 PLEKHM1
Miserableness 14.43 9 6 13.3 0.98 2.2e-06 AF131215.2 ANKK1 C1QTNF4 DRD2 FAM86B3P LINGO1 PLEKHM1 TTC12 UBXN2A
Medication: Blood pressure 3.79 3 2 4.4 0.00 1.0e+00 AF131215.2 FAM86B3P PLEKHM1
Supplements: Fish oil (including cod liver oil) 1.74 1 0 0.0 0.00 1.0e+00 FAM86B3P
Medication: Bendroflumethiazide 3.51 3 0 0.0 0.00 1.0e+00 AF131215.2 C1QTNF4 FAM86B3P
Medication: Paracetamol 4.56 3 1 2.2 0.00 1.0e+00 MED19 PLEKHM1 UBXN2A
Alcohol drinker status: Never 2.21 1 0 0.0 0.00 1.0e+00 C1QTNF4
Basal metabolic rate 2.03 4 2 4.4 -1.00 2.3e-03 AF131215.2 FAM86B3P LIN28B UBXN2A
Leg fat percentage (left) 4.61 7 2 4.4 0.06 9.0e-01 AF131215.2 ANKK1 AREL1 C1QTNF4 FAM86B3P KLHL29 TTC12
Arm fat-free mass (left) 2.02 3 2 4.4 0.00 1.0e+00 AF131215.2 FAM86B3P UBXN2A
Number of operations (self-reported) 3.00 1 0 0.0 0.00 1.0e+00 LIN28B
Average weekly beer plus cider intake 3.27 2 0 0.0 0.00 1.0e+00 AF131215.2 FAM86B3P
Irritability 9.44 6 3 6.7 0.97 1.3e-03 AF131215.2 ANKK1 AREL1 DRD2 FAM86B3P PLEKHM1
Risk taking 2.99 1 0 0.0 0.00 1.0e+00 AF131215.2
Fractured/broken bones in last 5 years 1.86 1 0 0.0 0.00 1.0e+00 PLEKHM1
Diastolic blood pressure, automated reading 3.77 3 2 4.4 0.00 1.0e+00 AF131215.2 C1QTNF4 FAM86B3P
Ever depressed for a whole week 2.82 1 0 0.0 0.00 1.0e+00 PLEKHM1
Vascular/heart problems diagnosed by doctor 3.31 4 1 2.2 0.68 3.2e-01 AF131215.2 C1QTNF4 FAM86B3P PLEKHM1
Pain experienced in last month 2.16 2 0 0.0 0.00 1.0e+00 MED19 PLEKHM1
Alcohol drinker status: Previous 2.58 1 0 0.0 0.00 1.0e+00 ATF4
Impedance of whole body 5.00 6 5 11.1 0.39 4.5e-01 AF131215.2 AREL1 FAM86B3P LIN28B PLEKHM1 UBXN2A
Leg fat mass (left) 3.70 5 3 6.7 -0.32 6.1e-01 AF131215.2 ANKK1 C1QTNF4 FAM86B3P TTC12
Arm predicted mass (left) 2.02 3 2 4.4 0.00 1.0e+00 AF131215.2 FAM86B3P UBXN2A

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 3 0.086 1.5
GTEx Adipose Visceral Omentum 2 0.098 1.6
GTEx Adrenal Gland 1 0.069 1.6
GTEx Artery Aorta 2 0.067 1.5
GTEx Artery Coronary 2 0.169 1.7
GTEx Artery Tibial 2 0.053 1.5
GTEx Brain Caudate basal ganglia 0 0.000 1.7
GTEx Brain Cerebellar Hemisphere 0 0.000 1.6
GTEx Brain Cerebellum 2 0.101 1.5
GTEx Brain Cortex 2 0.193 1.7
GTEx Brain Frontal Cortex BA9 2 0.216 1.6
GTEx Brain Hippocampus 1 0.191 1.7
GTEx Brain Hypothalamus 2 0.339 1.5
GTEx Brain Nucleus accumbens basal ganglia 0 0.000 1.6
GTEx Brain Putamen basal ganglia 1 0.160 1.6
GTEx Breast Mammary Tissue 1 0.051 1.5
GTEx Breast Mammary Tissue (Male) 2 0.168 1.4
GTEx Breast Mammary Tissue (Female) 0 0.000 1.6
GTEx Cells EBV-transformed lymphocytes 4 0.281 1.7
GTEx Cells Transformed fibroblasts 3 0.071 1.5
GTEx Colon Sigmoid 2 0.137 1.6
GTEx Colon Transverse 1 0.048 1.6
GTEx Esophagus Gastroesophageal Junction 1 0.069 1.6
GTEx Esophagus Mucosa 1 0.030 1.5
GTEx Esophagus Muscularis 1 0.031 1.6
GTEx Heart Atrial Appendage 1 0.063 1.7
GTEx Heart Left Ventricle 2 0.131 1.6
GTEx Liver 1 0.139 1.6
GTEx Lung 1 0.035 1.5
GTEx Muscle Skeletal 5 0.173 1.5
GTEx Nerve Tibial 0 0.000 1.5
GTEx Ovary 0 0.000 1.6
GTEx Pancreas 2 0.123 1.6
GTEx Pituitary 1 0.090 1.6
GTEx Prostate 2 0.240 1.6
GTEx Skin Not Sun Exposed Suprapubic 2 0.081 1.6
GTEx Skin Sun Exposed Lower leg 4 0.110 1.5
GTEx Small Intestine Terminal Ileum 2 0.434 1.9
GTEx Spleen 2 0.142 1.6
GTEx Stomach 1 0.069 1.6
GTEx Testis 6 0.190 1.6
GTEx Thyroid 2 0.050 1.5
GTEx Uterus 4 0.705 1.9
GTEx Vagina 0 0.000 1.6
GTEx Whole Blood 1 0.050 1.5
METSIM Adipose 2 0.043 1.4
NTR Blood 0 0.000 1.5
ROSMAP Brain Pre-frontal Cortex 3 0.068 1.6
YFS Blood 3 0.065 1.4
CommonMind Brain Pre-frontal Cortex 3 0.056 1.5
The Cancer Genome Atlas Bladder Urothelial Carcinoma 0 0.000 1.5
The Cancer Genome Atlas Breast Invasive Carcinoma 1 0.023 1.4
The Cancer Genome Atlas Cervical Squamous Cell Carcinoma 0 0.000 1.4
The Cancer Genome Atlas Colon Adenocarcinoma 2 0.097 1.5
The Cancer Genome Atlas Esophageal Carcinoma 1 0.146 1.6
The Cancer Genome Atlas Glioblastoma Multiforme 0 0.000 1.4
The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma 1 0.037 1.4
The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma 1 0.024 1.4
The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma 0 0.000 1.5
The Cancer Genome Atlas Brain Lower Grade Glioma 1 0.023 1.4
The Cancer Genome Atlas Liver Hepatocellular Carcinoma 0 0.000 1.5
The Cancer Genome Atlas Lung Adenocarcinoma 2 0.068 1.5
The Cancer Genome Atlas Lung Squamous Cell Carcinoma 0 0.000 1.5
The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma 1 0.063 1.4
The Cancer Genome Atlas Pancreatic Adenocarcinoma 0 0.000 1.5
The Cancer Genome Atlas Pheochromocytoma and Paraganglioma 1 0.075 1.4
The Cancer Genome Atlas Prostate Adenocarcinoma 1 0.022 1.5
The Cancer Genome Atlas Rectum Adenocarcinoma 0 0.000 1.5
The Cancer Genome Atlas Soft Tissue Sarcoma 0 0.000 1.5
The Cancer Genome Atlas Skin Cutaneous Melanoma 0 0.000 1.5
The Cancer Genome Atlas Stomach Adenocarcinoma 0 0.000 1.5
The Cancer Genome Atlas Testicular Germ Cell Tumors 1 0.078 1.4
The Cancer Genome Atlas Thyroid Carcinoma 0 0.000 1.5
The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma 0 0.000 1.3