Best TWAS P=2.96e-10 · Best GWAS P=2.07e-07 conditioned to 0.0067
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CEP170 | 0.05 | 0.02 | bslmm | 378 | 0.03 | 1.9e-04 | -2.3 | 6.3 | 3.0e-10 | -0.44 | 0.24 | 0.31 | TRUE |
| 2 | CommonMind | Brain Pre-frontal Cortex | SDCCAG8 | 0.13 | 0.10 | enet | 32 | 0.11 | 5.6e-13 | -4.4 | 5.3 | 1.1e-07 | -0.34 | 0.29 | 0.69 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | AKT3 | 0.02 | 0.00 | blup | 155 | 0.00 | 3.2e-01 | -4.6 | -5.2 | 1.5e-07 | 0.85 | 0.03 | 0.73 | FALSE |