Best TWAS P=4.62e-09 · Best GWAS P=2.14e-06 conditioned to 0.177
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Coronary | B3GALTL | 0.32 | 0.06 | enet | 12 | 0.20 | 2.5e-07 | -4.2 | -5.6 | 1.6e-08 | 0.69 | 0.04 | 0.90 | FALSE |
2 | GTEx | Artery Tibial | B3GALTL | 0.22 | 0.05 | lasso | 7 | 0.14 | 2.6e-11 | 3.4 | -5.4 | 7.8e-08 | 0.76 | 0.03 | 0.95 | FALSE |
3 | GTEx | Colon Sigmoid | B3GALTL | 0.34 | 0.12 | enet | 32 | 0.14 | 1.7e-05 | -4.7 | -5.9 | 4.6e-09 | 0.63 | 0.02 | 0.95 | TRUE |
4 | GTEx | Esophagus Muscularis | B3GALTL | 0.23 | 0.10 | lasso | 6 | 0.11 | 3.0e-07 | -4.2 | -5.5 | 4.0e-08 | 0.82 | 0.03 | 0.95 | FALSE |
5 | GTEx | Skin Sun Exposed Lower leg | B3GALTL | 0.15 | 0.02 | enet | 9 | 0.02 | 1.0e-02 | -4.7 | -5.8 | 7.8e-09 | 0.76 | 0.02 | 0.95 | FALSE |
6 | GTEx | Stomach | B3GALTL | 0.18 | 0.00 | lasso | 7 | 0.04 | 4.4e-03 | 3.4 | -5.4 | 8.7e-08 | 0.70 | 0.04 | 0.77 | FALSE |
7 | The Cancer Genome Atlas | Breast Invasive Carcinoma | B3GALTL | 0.02 | 0.00 | blup | 105 | 0.01 | 1.9e-03 | -4.6 | -5.4 | 6.4e-08 | 0.75 | 0.02 | 0.79 | FALSE |
8 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | B3GALTL | 0.09 | 0.05 | blup | 103 | 0.07 | 5.7e-08 | -4.7 | -5.3 | 1.0e-07 | 0.63 | 0.02 | 0.97 | FALSE |
9 | The Cancer Genome Atlas | Thyroid Carcinoma | B3GALTL | 0.14 | 0.17 | blup | 105 | 0.20 | 2.2e-19 | -4.7 | -5.3 | 1.5e-07 | 0.75 | 0.03 | 0.94 | FALSE |