Best TWAS P=2.15e-07 · Best GWAS P=4.8e-07 conditioned to 0.271
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Not Sun Exposed Suprapubic | MED19 | 0.12 | 0.05 | enet | 31 | 0.05 | 0.00075 | 5.0 | -5.2 | 2.3e-07 | -0.79 | 0.02 | 0.96 | TRUE |
2 | GTEx | Skin Sun Exposed Lower leg | ZDHHC5 | 0.05 | 0.03 | lasso | 8 | 0.02 | 0.00619 | 4.6 | 5.2 | 2.2e-07 | 0.91 | 0.06 | 0.91 | TRUE |